XIIth I.S.C.E.R.G. Symposium: Clermont-Ferrand 20-22 MAY 1974 (Documenta Ophthalmologica Proceedings Series)

ISBN 10: 9061931509 / ISBN 13: 9789061931508

Published by Springer

About this Item

424 pages. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9789061931508

Bibliographic Details

Title: XIIth I.S.C.E.R.G. Symposium: ...

Publisher: Springer

Binding: Paperback

Book Condition:New

Book Type: Paperback

About this title

Synopsis:

Strychnine and picrotoxin were tested as possible antagonists of two puta tive inhibitory transmitters in the retina: taurine and GABA, Strychnine was shown to antagonize the depressive action of taurine on the ERG b-wave, but it did not affect the depressive action of GABA. Conversely, picrotoxin had no effect on the depressive action of taurine on the ERG b-wave, but it antagonizes to some extent the depressive effect of GABA. These data, as well as those obtained through recording tectal evoked responses, lead to the conclusion that taurine and GABA do not act in the same way in retinal inhibitory synaptic transmission. REFERENCES CURTIS, D.R., AW. DUGGAN & G.A.R. JOflNSTON. Glycine, strychnine, picro toxine and spinal inhibition. Brain Res. 14, 759-762 (1969). CURTIS, D.R., L. HOSLI & G.AR. JOHNSTON. A pharmacological study of the depression of spinal neurones by glycine and related aminoacids. Exp. Brain Res. 6, 1-18 (1968 a). CURTIS, D.R., L.HOSLI, G.A.R. JOHNSTON & LH. JOHNSTON. The hyperpolariza tion of spinal motoneurones by glycine and related aminoacids. Exp. Brain Res. 5, 235-258 (1968 b). CURTIS, D.R. & A.K. TEBECIS. Bicuculline and thalamic inhibition. Exp. Brain Res. 16,210-218 (1972). DA VIDSON, N. & H. REISINE. Presynaptic inhibition in cuneate blocked by GABA antagonists. Nature New Biology 234,223-224 (1971)."