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Stuart, Ruth McEnery, 1849/1852-1917. E.W. Kemble [Edward Windsor Kemble], 1861-1933 (illustrator).

Published by New York, London: D. Appleton and Company, 1916. (1916)

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Hardcover
First Edition

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From: David Hallinan, Bookseller (Columbus, MS, U.S.A.)

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About this Item: New York, London: D. Appleton and Company, 1916., 1916. First edition, first printing (per Appleton's "1" on last text page 135 as was their contemporary practice). viii, 135 pages. Hardcover: H 18.25cm x L 11.25cm. Lacks dust jacket. Original cloth with vertical striped decoration to spine and front board, latter also has a pictorial paste-on with b/w vignette illustration of an African American banjo player; some rubbing and soiling, short blue ball point ink ticks on front board, light toning to spine with minor scuffing at ends. Gilt top edge; some toning to deckle fore-edge and bottom edge. Light foxing/toning to endpapers; past owner's ink signature at top of front pastedown; interior pages are clean. Binding shows some slight stress points between a few quires but remains firm. A very good- copy. Collection of dialect poetry by Marksville, Louisiana-born author Mary Routh McEnery Stuart who resided in New York City from the 1890s until her death in 1917. Seller Inventory # D17-8441

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FISCHER, Herman Emil (1852-1919) & Joseph von MERING (1849-1908).

Published by Urban & Schwarzenberg, 1903., Berlin & Vienna: (1903)

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Hardcover
First Edition

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From: Jeff Weber Rare Books, ABAA (Carlsbad, CA, U.S.A.)

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About this Item: Urban & Schwarzenberg, 1903., Berlin & Vienna:, 1903. 4to. (265 x 177 mm) pp. [97]-144. Modern black cloth boards, gilt-stamped spine title. Bookplate of Andras Gedeon. Fine. FIRST PRINTING of the discovery of diethyl barbituric acid. Fischer received the Nobel Prize in Chemistry in 1902. "Berlin chemist Emil Fischer and Joseph von Mering synthesized diethyl barbituric acid or barbitone (Veronal) in 1902. They described their discovery in "Ueber eine neue Klasse von Schlafmitteln", Therapie Gegenwart 44:97-101, 1903. The parent compound, barbituric acid, was first synthesised by Adolf von Baeyer in 1864, but barbituric acid is not itself pharmacologically active. Fischer and von Mering soon realized that their new drug was a sedative. Veronal represented a huge improvement on the medley of existing agents. It didn't taste unpleasant. It had few adverse side effects. Unlike foul-tasting potassium bromide, Veronal acted at therapeutic levels far beneath the toxic dose. Some 2,500 barbiturates were synthesized over the next century. More than fifty have been marketed as sedatives. In 1912, phenobarbital was introduced under the brand-name Luminal. From 1912 until around 1960 barbiturates were the mainstay of pharmacological treatments of anxiety and insomnia. The development of soluble barbiturates suitable for use as intravenous anaesthetics still lay in the future." [BLTC Research, UK]. Cole, Milestones of Anesthesia, 29; Garrison & Morton 1892; Gedeon, Science and technology in medicine, pp. 372-5. Seller Inventory # S9484

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FISCHER, Herman Emil (1852-1919) & Joseph von MERING (1849-1908).

Published by Urban & Schwarzenberg, 1903., Berlin & Wien: (1903)

Used
Softcover
First Edition

Quantity Available: 1

From: Jeff Weber Rare Books, ABAA (Carlsbad, CA, U.S.A.)

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About this Item: Urban & Schwarzenberg, 1903., Berlin & Wien:, 1903. 8vo. (175 x 115 mm) 16 pp.; two short marginal tears not affecting text. Original printed wrappers; centre fold mark. Exlib ink stamp on cover, bookplate of Andras Gedeon. Fine. FIRST SEPARATE EDITION of the discovery of diethyl barbituric acid. "Fischer and Mering investigate the hypnotic effect of various derivatives of barbituric acid and related substances⦠This led to the seminal discovery of the hypnotic action of diethylbarbituric acid." This work introduced an entirely new synthetic drug called Veronal, a barbiturate family still of major importance in clinical medicine. [Gedeon]. Garrison & Morton 1892; Gedeon, Science and technology in medicine, pp. 372-5. Seller Inventory # S9485

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