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Kuang-Oscar Hing-Sing Kuang-Oscar Hing-Sing W Kuang-Oscar Hing-Sing Yu Yu

Published by VDM Verlag 2011-03-30 (2011)

ISBN 10: 3639344634 ISBN 13: 9783639344639

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From: Blackwell's (Oxford, OX, United Kingdom)

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Item Description: VDM Verlag 2011-03-30, 2011. paperback. Book Condition: New. Bookseller Inventory # 9783639344639

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Kuang-Oscar Hing-Sing Kuang-Oscar Hing-Sing W Kuang-Oscar Hing-Sing Yu Yu

Published by VDM Verlag (2011)

ISBN 10: 3639344634 ISBN 13: 9783639344639

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From: Books2Anywhere (Fairford, GLOS, United Kingdom)

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Item Description: VDM Verlag, 2011. PAP. Book Condition: New. New Book. Delivered from our UK warehouse in 3 to 5 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Bookseller Inventory # LQ-9783639344639

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Kuang-Oscar Hing-Sing Kuang-Oscar Hing-Sing W Kuang-Oscar Hing-Sing Yu Yu

Published by LAP Lambert Academic Publishing 2011-07-03 (2011)

ISBN 10: 3844386769 ISBN 13: 9783844386769

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Item Description: LAP Lambert Academic Publishing 2011-07-03, 2011. paperback. Book Condition: New. Bookseller Inventory # 9783844386769

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Kuang-Oscar Hing-Sing Kuang-Oscar Hing-Sing W Kuang-Oscar Hing-Sing Yu Yu

Published by VDM Verlag (2011)

ISBN 10: 3639344634 ISBN 13: 9783639344639

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From: Pbshop (Wood Dale, IL, U.S.A.)

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Item Description: VDM Verlag, 2011. PAP. Book Condition: New. New Book. Shipped from US within 10 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Bookseller Inventory # IQ-9783639344639

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Kuang-Oscar Hing-Sing Kuang-Oscar Hing-Sing W Kuang-Oscar Hing-Sing Yu Yu

Published by LAP Lambert Academic Publishing (2011)

ISBN 10: 3844386769 ISBN 13: 9783844386769

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Item Description: LAP Lambert Academic Publishing, 2011. PAP. Book Condition: New. New Book. Delivered from our UK warehouse in 3 to 5 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Bookseller Inventory # LQ-9783844386769

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Kuang-Oscar Hing-Sing Kuang-Oscar Hing-Sing W Kuang-Oscar Hing-Sing Yu Yu

Published by LAP Lambert Academic Publishing (2011)

ISBN 10: 3844386769 ISBN 13: 9783844386769

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From: Pbshop (Wood Dale, IL, U.S.A.)

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Item Description: LAP Lambert Academic Publishing, 2011. PAP. Book Condition: New. New Book. Shipped from US within 10 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Bookseller Inventory # IQ-9783844386769

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Kuang-Oscar Hing-Sing Kuang-Oscar Hing-Sing W Kuang-Oscar Hing-Sing Yu Yu, Des Richardson

Published by VDM Verlag, Germany (2011)

ISBN 10: 3639344634 ISBN 13: 9783639344639

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From: The Book Depository EURO (London, United Kingdom)

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Item Description: VDM Verlag, Germany, 2011. Paperback. Book Condition: New. Language: English . Brand New Book. Previous studies demonstrated that HDpT chelators have potent anti-tumour activity. We have now designed and generated two new groups of chelators, HBpT and HNBpT. Comparing the three series of chelators, the HBpT analogues displayed highest anti- proliferative efficacy against SK-N-MC neuroepithelioma cells and was greater than other well known chelators (DFO, Triapine and 311). Three analogues of the HBpT series displayed much greater anti-proliferative activity against SK-N-MC cells than normal MRC-5 fibroblasts, indicating their selectivity against tumour cells. Structure-activity relationships examination demonstrated that lipophilicity and redox cycling activity were important factors in generating potent chelators. Redox activity determined by ascorbate oxidation and benzoate hydroxylation assays showed that the HBpT ligands were the most active chelators. Microarray studies using DFO and HDp44mT, demonstrated up- regulation of the gene in cell cycle arrest, while genes in cancer progression were down-regulated. The current studies have identified a novel group of chelators with the greatest activity of all chelators previously prepared in our lab. Bookseller Inventory # KNV9783639344639

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Kuang-O Yu (Autor), W. Yu (Autor) and Kuang-Oscar Yu (Herausgeber:

Published by CRC Press, (2001)

ISBN 10: 0824788818 ISBN 13: 9780824788810

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Item Description: CRC Press, 2001. Hardcover. Book Condition: Sehr gut. Buch ist leicht verlagert (wellig), Cover leicht berieben, kleine Lagerspuren am Buch, Inhalt einwandfrei und ungelesen 123440 Sprache: Englisch Gewicht in Gramm: 1135. Bookseller Inventory # 357922

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Kuang-Oscar Hing-Sing Kuang-Oscar Hing-Sing W Kuang-Oscar Hing-Sing Yu Yu, Des Richardson

Published by LAP Lambert Academic Publishing, Germany (2011)

ISBN 10: 3844386769 ISBN 13: 9783844386769

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From: The Book Depository EURO (London, United Kingdom)

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Item Description: LAP Lambert Academic Publishing, Germany, 2011. Paperback. Book Condition: New. Language: English . Brand New Book. Previous studies demonstrated that thiosemicarbazone iron chelator possessed potent and selective anti-cancer activity. In this study, the in vitro and in vivo anti-tumor efficacy and tolerability of 2-benzoylpyridine thiosemicarbazone (BpT) iron chelators were examined. The BpT chelators were tested against human lung cancer cells in vitro and tumor xenografts in mice. The toxicity of Bp44mT and its effects on the expression of iron-regulated molecules involved in growth and cell cycle control were investigated. The results shown demonstrate the anti-tumor activity of the orally-active Bp44mT chelator, which was well tolerated in vivo. Furthermore, the cytotoxicity of thiosemicarbazones is likely to be mediated, in part, through their redox activity and effects on multiple thiol-containing systems. In terms of signal transduction, iron chelation may influence the MAPK signaling pathways via the thioredoxin-ASK1 signalosome. These results emphasize the importance of redox-activity of thiosemicarbazone chelators. Considering their potent anti-tumor activity, these investigations facilitate the future development of promising thiosemicarbazone iron chelators as anti-cancer agents. Bookseller Inventory # LIB9783844386769

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Published by CRC Press (2001)

ISBN 10: 0824788818 ISBN 13: 9780824788810

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From: Irish Booksellers (Rumford, ME, U.S.A.)

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Item Description: CRC Press, 2001. Hardcover. Book Condition: New. book. Bookseller Inventory # M0824788818

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Editor-Kuang-Oscar Yu

Published by CRC Press (2001)

ISBN 10: 0824788818 ISBN 13: 9780824788810

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From: Ergodebooks (RICHMOND, TX, U.S.A.)

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Item Description: CRC Press, 2001. Hardcover. Book Condition: Used: Very Good. Bookseller Inventory # SONG0824788818

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Kuang-Oscar Yu (Editor)

Published by CRC Press (2001)

ISBN 10: 0824788818 ISBN 13: 9780824788810

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Item Description: CRC Press, 2001. Hardcover. Book Condition: New. Bookseller Inventory # DADAX0824788818

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YU, KUANG-OSCAR.

Published by CRC Press (2001)

ISBN 10: 0824788818 ISBN 13: 9780824788810

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From: Herb Tandree Philosophy Books (Stroud, GLOS, United Kingdom)

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Item Description: CRC Press, 2001. Hardback. Book Condition: NEW. 9780824788810 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Bookseller Inventory # HTANDREE0205343

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Yu, Kuang-Oscar (Edited by)

Published by Marcel Dekker Inc (2001)

ISBN 10: 0824788818 ISBN 13: 9780824788810

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From: Revaluation Books (Exeter, United Kingdom)

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Item Description: Marcel Dekker Inc, 2001. Hardcover. Book Condition: Brand New. 1st edition. 720 pages. 9.25x6.00x1.50 inches. In Stock. Bookseller Inventory # __0824788818

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Results (1 - 14) of 14