Nagl Sylvia (36 results)

1st ed. 17 x 25 cm. 300 pages. HC Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Sprache: Englisch.

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Hardcover. Condition: new. Hardcover. "The development and application of bioinformatics tools to basic and translational cancer research is, in fact, a rapidly expanding field that deserves a timely review. Therefore, a publication of this type is needed. The editors have done an excellent job in recruiting well-established scientists to author the various chapters of the book." Dieter Naf, Jackson Laboratory, USA Cancer bioinformatics is now emerging as a new interdisciplinary field, which is facilitating an unprecedented synthesis of knowledge arising from the life and clinical sciences. This groundbreaking title provides a comprehensive and up-to-date account of the enormous range of bioinformatics for cancer therapy development from the laboratory to clinical trials. It functions as a guide to integrated data exploitation and synergistic knowledge discovery, and support the consolidation of the interdisciplinary research community involved. "The development and application of bioinformatics tools to basic and translational cancer research is, in fact, a rapidly expanding field that deserves a timely review. Therefore, a publication of this type is needed. The editors have done an excellent job in recruiting well-established scientists to author the various chapters of the book. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Model integration - the process by which different modelling efforts can be brought together to simulate the target system - is a core technology in the field of Systems Biology. In the work presented here model integration was addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that model integration poses, namely that of paradigm (the formalism on which a model is based), focus (the real-world system the model represents) and scale.A two-tier model integration strategy, including a knowledge-driven approach to address model semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distilling a set of abstract classes and properties. These can accurately describe model behaviour and hence describe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour is decomposed into an agent-based system by translating the models into local interaction rules.The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects, which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is self-supporting. It also includes an in-depth current bibliography to relevant research papers and literature. The review of the current state of the art in tumour modelling provides added value.

Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Model integration - the process by which different modelling efforts can be brought together to simulate the target system - is a core technology in the field of Systems Biology. In the work presented here model integration was addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that model integration poses, namely that of paradigm (the formalism on which a model is based), focus (the real-world system the model represents) and scale.A two-tier model integration strategy, including a knowledge-driven approach to address model semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distilling a set of abstract classes and properties. These can accurately describe model behaviour and hence describe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour is decomposed into an agent-based system by translating the models into local interaction rules.The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects, which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is self-supporting. It also includes an in-depth current bibliography to relevant research papers and literature. The review of the current state of the art in tumour modelling provides added value.

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Condition: New. "The development and application of bioinformatics tools to basic and translational cancer research is, in fact, a rapidly expanding field that deserves a timely review. Therefore, a publication of this type is needed. The editors have done an excellent job in recruiting well-established scientists to author the various chapters of the book. Editor(s): Nagl, Sylvia. Num Pages: 300 pages, illustrations. BIC Classification: MBF; MJCL; PSAK. Category: (P) Professional & Vocational. Dimension: 250 x 180 x 24. Weight in Grams: 728. . 2006. . . . .

Hardcover. Condition: Brand New. 1st edition. 300 pages. 10.00x7.00x1.00 inches. In Stock.

Hardback. Condition: New. New copy - Usually dispatched within 3 working days.

Hardback. Condition: New. "The development and application of bioinformatics tools to basic and translational cancer research is, in fact, a rapidly expanding field that deserves a timely review. Therefore, a publication of this type is needed. The editors have done an excellent job in recruiting well-established scientists to author the various chapters of the book." -Dieter Naf, Jackson Laboratory, USA Cancer bioinformatics is now emerging as a new interdisciplinary field, which is facilitating an unprecedented synthesis of knowledge arising from the life and clinical sciences. This groundbreaking title provides a comprehensive and up-to-date account of the enormous range of bioinformatics for cancer therapy development from the laboratory to clinical trials. It functions as a guide to integrated data exploitation and synergistic knowledge discovery, and support the consolidation of the interdisciplinary research community involved.

Gebunden. Condition: New. .recommended for purchase for medical, academic or special libraries serving basic or clinical cancer researchers and bioinformaticists. (E-STREAMS, September 2007) .good reading for anyone entering into some aspect of cancer research, whether it is b.

Hardcover. Condition: new. Hardcover. "The development and application of bioinformatics tools to basic and translational cancer research is, in fact, a rapidly expanding field that deserves a timely review. Therefore, a publication of this type is needed. The editors have done an excellent job in recruiting well-established scientists to author the various chapters of the book." Dieter Naf, Jackson Laboratory, USA Cancer bioinformatics is now emerging as a new interdisciplinary field, which is facilitating an unprecedented synthesis of knowledge arising from the life and clinical sciences. This groundbreaking title provides a comprehensive and up-to-date account of the enormous range of bioinformatics for cancer therapy development from the laboratory to clinical trials. It functions as a guide to integrated data exploitation and synergistic knowledge discovery, and support the consolidation of the interdisciplinary research community involved. "The development and application of bioinformatics tools to basic and translational cancer research is, in fact, a rapidly expanding field that deserves a timely review. Therefore, a publication of this type is needed. The editors have done an excellent job in recruiting well-established scientists to author the various chapters of the book. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Condition: New. "The development and application of bioinformatics tools to basic and translational cancer research is, in fact, a rapidly expanding field that deserves a timely review. Therefore, a publication of this type is needed. The editors have done an excellent job in recruiting well-established scientists to author the various chapters of the book. Editor(s): Nagl, Sylvia. Num Pages: 300 pages, illustrations. BIC Classification: MBF; MJCL; PSAK. Category: (P) Professional & Vocational. Dimension: 250 x 180 x 24. Weight in Grams: 728. . 2006. . . . . Books ship from the US and Ireland.

Buch. Condition: Neu. Neuware - The emerging field of cancer bioinformatics is facilitating an unprecedented synthesis of knowledge arising from the life and clinical sciences. The complexity of the questions being addressed requires experts from diverse backgrounds to engage in close and ongoing discourse and collaboration. They therefore need to be familiar with the research questions, terminology and methodology of the specialists in related subject areas.The primary aim of the book is to provide a comprehensive and up-to-date account of the enormous range of bioinformatics techniques now being developed for cancer research and therapy, from the laboratory to clinical trials. It will function as a guide to integrated data exploitation and synergistic knowledge discovery, and support the consolidation of the multidisciplinary research community involved.The book features a balanced range of topics, including both well-established techniques and emergent approaches in genomics, systems biology and e-science. Each chapter delivers an overview of the topic, combined with more detailed technical descriptions of key aspects of informatics, biology and clinical science. With contributions from clinical oncologists, research scientists, bioinformaticians and mathematical modellers, the book will facilitate scientific dialogue and collaboration across disciplinary boundaries. Finally, three chapters on the ethical and legal implications of cancer bioinformatics provide an expanded view of these groundbreaking developments and how they may impact on patients and other health care stakeholders.This multidisciplinary book will be of interest to a broad audience including clinical oncologists, basic researchers in both academia and industry, computer scientists/bioinformaticians, clinical trial managers, ethicists and ethics boards.

Buch. Condition: Neu. Cancer Bioinformatics | From Therapy Design to Treatment | Sylvia Nagl | Buch | [.] of Contributors.SECTION I CANCER SYSTEMS.1 A Path to Knowledge: from Data to Complex Systems Models of Cancer (Sylvia Nagl).2 Theory of Cancer Robustness (Hiroaki Kitano).3 Developing an Integrated Informatics Platform for Cancer Research (R | Englisch | 2006 | Wiley | EAN 9780470863046 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu.

Hardback. Condition: New. "The development and application of bioinformatics tools to basic and translational cancer research is, in fact, a rapidly expanding field that deserves a timely review. Therefore, a publication of this type is needed. The editors have done an excellent job in recruiting well-established scientists to author the various chapters of the book." -Dieter Naf, Jackson Laboratory, USA Cancer bioinformatics is now emerging as a new interdisciplinary field, which is facilitating an unprecedented synthesis of knowledge arising from the life and clinical sciences. This groundbreaking title provides a comprehensive and up-to-date account of the enormous range of bioinformatics for cancer therapy development from the laboratory to clinical trials. It functions as a guide to integrated data exploitation and synergistic knowledge discovery, and support the consolidation of the interdisciplinary research community involved.

Hardcover. Condition: new. Hardcover. "The development and application of bioinformatics tools to basic and translational cancer research is, in fact, a rapidly expanding field that deserves a timely review. Therefore, a publication of this type is needed. The editors have done an excellent job in recruiting well-established scientists to author the various chapters of the book." Dieter Naf, Jackson Laboratory, USA Cancer bioinformatics is now emerging as a new interdisciplinary field, which is facilitating an unprecedented synthesis of knowledge arising from the life and clinical sciences. This groundbreaking title provides a comprehensive and up-to-date account of the enormous range of bioinformatics for cancer therapy development from the laboratory to clinical trials. It functions as a guide to integrated data exploitation and synergistic knowledge discovery, and support the consolidation of the interdisciplinary research community involved. "The development and application of bioinformatics tools to basic and translational cancer research is, in fact, a rapidly expanding field that deserves a timely review. Therefore, a publication of this type is needed. The editors have done an excellent job in recruiting well-established scientists to author the various chapters of the book. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.