springer us dez 2001 (63 results)

Buch. Condition: Neu. Neuware - During several decades of this century, the classical physiological studies on the cardiovascular system have greatly improved our knowledge on the function of this system under normal and pathological conditions. This knowledge was the basis of the breakthrough for diagnostic techniques like the Swan-Ganz catheter, coronary arteriography, left and right heart biopsies, and invasive measurements of contractility, as well as therapeutic tools including aortocoronary bypass surgery, percutanous transluminal coronary angioplasty, and a broad field of pharmacological interventions for the whole spectrum of cardiovascular diseases, especially chronic heart failure. It was during the last decade that the scientific world focused on the evolution of molecular biology of the cardiovascular system so that cardiovascular physiology seemed to become less important. Regarding the myocardium, molecular alterations of important functional proteins (phenotype changes), as well as signal transduction pathways of contractility and cardiac growth have been elucidated. The functional importance of a number of genes has undoubtedly been proven with the help of transgenic animals. Mechanics and Energetics of the Myocardium provides an overview for those researchers and practioners interested in the broad field of molecular biology and physiology of the cardiovascular system.

Buch. Condition: Neu. Neuware - This volume contains review articles and original results obtained in various fields of modern science using mathematical simulation methods. The basis of the articles are the plenary and some section reports that were made and discussed at the Fourth International Mathematical Simulation Conference, held in Moscow on June 27 through July 1, 2000. The conference was devoted to the following scientific areas: - mathematical and computer discrete systems models; - non-linear excitation in condensed media; - complex systems evolution; - mathematical models in economics; - non-equilibrium processes kinematics; - dynamics and structure of the molecular and biomolecular systems; - mathematical transfer models in non-linear systems; - numerical simulation and algorithms; - turbulence and determined chaos; - chemical physics of polymer. This conference was supported by the Russian Ministry of Education, Russian foundation for Basic Research and Federal Program 'Integration'. This volume contains the following sections: 1. models of non-linear phenomena in physics; 2. numerical methods and computer simulations; 3. mathematical computer models of discrete systems; 4. mathematical models in economics; 5. non-linear models in chemical physics and physical chemistry; 6. mathematical models of transport processes in complex systems. In Sections One and Five a number of fundamental and sufficiently general problems, concerning real physical and physical-chemical systems simulation, is discussed.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -I have often wondered if the opposition to women's choosing to abort a pregnancy masks a fear of women choosing to have and raise children on their own. When a woman separatesmotherhood from marriage, she claims a freedom in the realm of intimate rela tionships that may be as fundamental as Freedom of Conscience or Freedom of Association. Yet, we do not usually think about women's decisions concerning motherhood in these terms. In a pair of remarkable studies begun in the 1980s, Ruth Linn-pregnant at the time, and married to a medical officer in the Israeli army-took the study of moral psychology into two highly controversial arenas of moral action: Israeli soldiers who refused to serve in Lebanon and single women who refused to remain childless. While conscientious objection to war has long been recognized as an act ofmoral resistance and courage,women who question societal norms and values linking motherhood with marriage, are typically dismissed as bad women. Rather than approaching these questions in the abstract, Linn chose to inter view women who made the decision to have and raise children on their own. What she found was that in the course of making this decision, women came to see themselves as moral resisters. In freeing their childbearing capability from men's control,they were also freeing their capacity to love. The very title of this book, Mature Unwed Mothers, calls us to think about what we mean by maturity on the part of mothers. 188 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Interest in marine mammals has increased dramatically in the last few decades, as evidenced by the number of books, scientific papers, and conferences devoted to these animals. Nowadays, a conference on marine mammals can attract between one and two thousand scientists from around the world. This upsurge of interest has resulted in a body of knowledge which, in many cases, has identified major conservation problems facing particular species. At the same time, this knowledge and the associated activities of environmental organisations have served to introduce marine mammals to a receptive public, to the extent that they are now perceived by many as the living icons of biodiversity conservation. Much of the impetus for the current interest in marine mammal conservation comes from 'Save the Whale' campaigns started in the 1960s by environmental groups around the world, in response to declining whale populations after over-exploitation by humans. This public pressure led to an international moratorium on whaling recommended in 1972 by the United Nations Conference on the Human Environment in Stockholm, Sweden, and eventually adopted by the International Whaling Commission ten years later. This moratorium largely holds sway to this day, and further protective measures have included the delimitation of extensive areas of the Indian Ocean (1979) and Southern Ocean (1994) as whale sanctuaries. 644 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This text has been out of print since 1990; it was originally published by Solomon Press in 1987. Several experts in the field have verified that the information in the book remains constant; nothing has, or will, change in the basic science of musical sound. It explains the science of musical sound without the encumbrance of detailed mathematics. It will appeal to music lovers as well as students of music and students of physics. It can easily be promoted with our physics program. 346 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Employing both large-scale surveys and in-depth interviews, the authors document the mental health effects on workers caused by the closure of four General Motor plants. They paint a portrait of how the social context in which these workers lived played a critical role in their experiences of unemployment or of keeping their jobs when others around them lost theirs. More than simply a study of unemployment and mental health, this book is also a story of coping and resilience. 252 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With the passing of Clifford Collier Clogg at the age of 45 on May 7th 1995, the world lost a talented sociologist, demographer, and statistician all at once. In addition to being a considerable talent in each of these three disciplines, and perhaps more importantly, Cliff was the type of person who brought to gether diverse elements and scholars from all three. Cliff was also a consum mate mentor, nurturing ideas and students and always striving to bring out the best in both. Perhaps nothing illustrates the stature, impact, and respect others held for Cliff more than the fact that never before-and never since has an individual been honored at the time of his death with ceremonies from the national associations of all three of these disciplines. The purpose of this book is to introduce to a broad constituency of social scientists and their students some of the basic ideas in the study of the labor force that Cliff and his colleagues had grappled with. At the time of Cliff's death, he was perhaps better known for his methodological contributions to sociology and demography than he was for his substantive contributions to the study of social stratification and the labor force. Our goal is to highlight Cliff's substantive contributions to sociology and demography by telling the cumulative story of his research and adding updated analysis that advances the story beyond the early 1980s to the mid-1990s. 276 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is a textbook for a year-long graduate level course in All research universities have applied mathematics for scientists and engineers. such a course, which could be taught in different departments, such as mathematics, physics, or engineering. I volunteered to teach this course when I realized that my own research students did not learn much in this course at my university. Then I learned that the available textbooks were too introduc tory. While teaching this course without an assigned text, I wrote up my lecture notes and gave them to the students. This textbook is a result of that endeavor. When I took this course many, many, years ago, the primary references were the two volumes of P. M. Morse and H. Feshbach, Methods of Theoretical Physics (McGraw-Hill, 1953). The present text returns the contents to a similar level, although the syllabus is quite different than given in this venerable pair of books. 388 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume represents a collection of lectures delivered by outstanding specialists in the fields of biophysics and of related scientific disciplines th during the 7 International Summer School on Biophysics held in Rovinj, Croatia from 14 to 25 September 2000 under the title 'Super molecular Structure and Function '. This scientific-educational event was organized by the Ruder Boskovic Institute ofZagreb, Croatia with substantial material and intellectual support of a number of national and international institutions including the Croatian Biophysical Society (CBS), the International Union of Pure and Applied Biophysics (IUPAB), the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the UNESCO Venice Office - Regional Office for Science and Technology for Europe (UVO-ROSTE). The seventh edition of the series of International Summer Schools on Biophysics, which was started in 198I, attracted more than 120 young researchers and post-graduate students coming from 27 countries of Europe, Asia, Africa and Latin America. Twenty-five outstanding experts in pure and applied biophysics presented the most advanced knowledge ofthis very interdisciplinary area of science during their lectures and round tables. It was commonly acknowledge that the Summer School achieved great success and fully reached its objectives. The success of the Rovinj Summer School was also due to the constantly growing attention being paid by scientific communities to younger generations of scientists, thanks also to the major outcomes of the World Conference on Science 'Science for the Twenty-first Century: A New Commitment' held by UNESCO and ICSU in Budapest, Hungary in June 1999. 252 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Inspired by the eternal beauty and truth of the laws governing the run of stars on heavens over his head, and spurred by the idea to catch, perhaps for the smallest fraction of the shortest instant, the Eternity itself, man created such masterpieces of human intellect like the Platon's world of ideas manifesting eternal truths, like the Euclidean geometry, or like the Newtonian celestial me chanics. However, turning his look to the sub-lunar world of our everyday efforts, troubles, sorrows and, from time to time but very, very seldom, also our successes, he saw nothing else than a world full of uncertainty and tem porariness. One remedy or rather consolation was that of the deep and sage resignation offered by Socrates: I know, that I know nothing. But, happy or unhappy enough, the temptation to see and to touch at least a very small por tion of eternal truth also under these circumstances and behind phenomena charged by uncertainty was too strong. Probability theory in its most sim ple elementary setting entered the scene. It happened in the same, 17th and 18th centuries, when celestial mechanics with its classical Platonist paradigma achieved its greatest triumphs. The origins of probability theory were inspired by games of chance like roulettes, lotteries, dices, urn schemata, etc. and probability values were simply defined by the ratio of successful or winning results relative to the total number of possible outcomes. 236 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Proceedings of the XIV World Meeting of the International Society for the Research on Aggression: Prevention and Control of Aggression and the Impact on its Victims, held in July 9-14, 2000, in Valencia, Spain. Aggression is an aspect of human society that has interested scientists for many decades, and their work has provided important knowledge about its causes and way to prevent and control this behavior. However, not only scientists but many professionals working in the wide spectrum of society, from family to international policy, are interested in having programs of interventions capable of reducing aggression and violence in our society. This comprehensive book is a compendium of most research approaches that are currently taking place in the field of aggression, focusing on the interventions to control and prevent this behavior and the impact on its victims. The chapters of the book include biological approaches to aggression, such as neuroanatomy, neurochemistry, neuroendocrinology, genetics and psychopathology; information about aggression in children and adolescents in different settings such as family, school and community; characteristics if aggression in specific relationships such as marital and sexual, and specific settings such as bars, prisons and traffic; and cultural approaches to aggression, social prejudice, war and programs of peace. Furthermore, a small number of representative chapters about victims are included, ranging from the impact of aggression on behavior and physiology in animal models to victims of war. As this book highlights, the interventions to prevent and control aggression have to be diverse (highly heterogenic) in order to deal with all aspects of human beings and society, ranging from pharmacological control in individuals to programs of peace to promote respect among people and among nations. Scientists, academics and professionals dealing with any facet of aggression and its impact on our society will obtain in this book information about the complexity of this research field and the ways to approach our objective: eliminate aggression from the human behavioral repertoire. 476 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -What is the archaeology of the body and how can it change the way we experience the past This book, one of the first to appear on the subject, records and evaluates the emergence of this new direction of cross-disciplinary research, and examines the potential of incorporating some of its insights into archaeology. It will be of interest to students, researchers, and teachers in archaeology, as well as in cognate disciplines such as anthropology and history. 284 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is based on my doctoral thesis at the Helsinki University of Technology. Several different projects during five years guided me from the basics of the RF IC design to the implementations of highly integrated radio receiver chips. Sharing time and effort between IC and system issues is not always straightforward. I have been lucky to follow both topics and share experiences with diligent and enthusiastic people having different specialities. As a result, this book will cover a wide range of different topics needed in the design of highly integrated radio receivers. Experiences from the first receiver prototypes for the third generation cellular systems form the basis of this book. Most of the issues are directly related to the early proposals of European and Japanese standardization organizations. For example, the chip rate was originally set to 4. 096 Mcps in a wide-band CDMA channel. I have kept that number in the book in most of the examples although it has been later changed to 3. 84 Mcps. I hope that the readers will accept that and the possible other incompabilities to the latest specifications. At least in the research phase the changes even in the most essential requirements are definitely not a rare incident and IC designers should be able to react and modify their designs as soon as they can. 256 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The author proposes a theory of the development of consciousness in which ego is the central agent of socialization and culture and the driving force behind individual self-control and self-regulation. He reviews the literature on identity and narrative; outlines the fields of intellectual, self, moral, and consciousness development; and discusses the evidence indicating that the development of consciousness trancends the limitations of conventional ego development. 228 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Exchange is a pervasive concept in everyday life, affecting phenomena as diverse as interpersonal relationships and market transactions. In addition, economists have used the concept in a highly specific and clearly delineated way. Against this background, Expanding the Economic Concept of Exchange sets out to expand the concept of exchange by crossing the boundaries laid down by economists and by examining the function played by deceptions, self-deceptions and illusions. The main motivation for expanding the concept of exchange was the realization that in the prototypical economic model deception is not taken into account. Hence, economists traditionally regard deception as some sort of irrationality, as a flaw in an otherwise perfectly rational process. Authors represented in this volume take a different approach examining deception as a constituent quality of exchange. This is shown by the contributions drawing on recent developments in economic theory, by those with an anthropological orientation, as well as by a contribution referring specifically to Adam Smith. An interrogation into deception is long overdue in economics. This volume prepares the ground for and makes the first contributions to explicitly acknowledging deceptions, self-deceptions and illusions as fundamental dimensions allowing us as economists to further research and develop the concept of change. A particular and perhaps unexpected focus of this volume lies on anthropology, because economics can clearly benefit from integrating selected results on deception from outside its expanding domain. It is primarily targeted at economists interested in institutional aspects of exchanges and social theory. In addition, the topic will find interested readers from anthropology, cultural studies, science studies, philosophy. 276 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Deng Feng Wang was born February 8, 1965 in Chongqing City, China and died August 15, 1999 while swimming with friends in the Atlantic Ocean off Island Beach State Park, New Jersey. In his brief life, he was to have an influence far beyond his years. On August 12th 2000, The Deng Feng Wang Memorial Conference was held at his alma mater, Princeton University, during which Deng Feng's mentors, collaborators and friends presented scientific talks in a testimonial to his tremendous influence on their work and careers. The first part of this volume contains proceedings contributions from the conference, with plenary talks by Nobel Laureate Professor Phil Anderson of Princeton University and leading Condensed Matter Theorists Professor Piers Coleman of Rutgers University and Professor Christian Gruber of the University of Lausanne. Other talks, given by collaborators, friends and classmates testify to the great breadth of Deng Feng Wang's influence, with remarkable connections shown between seemingly unrelated areas in physics such as Condensed Matter Physics, Superconductivity, One-Dimensional Models, Statistical Physics, Mathematical Physics, Quantum Field Theory, High Energy Theory, Nuclear Magnetic Resonance, Supersymmetry, M-Theory and String Theory, in addition to such varied fields outside of physics such as Oil Drilling, Mixed Signal Circuits and Neurology. The second part of the volume consists of reprints of some of Deng Feng Wang's most important papers in the areas of Condensed Matter Physics, Statistical Physics, Magnetism, Mathematical Physics and Mathematical Finance. This volume represents a fascinating synthesis of a wide variety of topics, and ultimately points to the universality of physics and of science as a whole. As such, it r epresents a fitting tribute to a remarkable individual, whose tragic death will never erase his enduring influence. 220 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Experimental Business Research includes papers that were presented at the First Asian Conference on Experimental Business Research held at the Hong Kong University of Science and Technology (HKUST), on December 7-10, 1999. The conference was organized by the Center for Experimental Business Research (cEBR) at the HKUST. The papers presented at the conference and a few others that were solicited especially for this volume contain original research on individual and interactive decision behavior in various branches of business research including, but not limited to, economics, marketing, management, finance, and accounting. Experimental Business Research is suitable as a secondary text for a graduate level course, and as a reference for researchers and practitioners in industry. 436 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Closed-End Investment Companies (CEICs) have experienced a significant revival of interest, both as investment vehicles and as the subject of academic research, over the past decade. This academic research has focused on the nature of closed-end funds' discounts and premiums and on the share price behavior of these firms. The first book by the authors, 'Closed-End Investment Companies: Issues and Answers,' addresses closed-end fund academic articles published prior to 1991. This second book addresses those articles that have appeared since that time. Closed-End Fund Pricing: Theories and Evidence is designed for the academic researcher interested in CEICs and the practitioner interested in using CEICs as an investment vehicle. The authors summarize the evolution of CEICs, present the factors thought to cause CEIC shares to trade at different levels from their net asset values, provide a complete survey of the recent academic literature on this topic, and summarize the current state of research on CEICs. 116 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the foreword to Supply Chain Structures, Professor Paul Zipkin notes three global changes that have enabled the recent vast developments in the field of supply chains. Moreover, these changes may be only the beginning and more change is likely in the fast-moving field of supply chain management. These global changes are: the explosive growth of the Internet; the growth in free-market economies with the corresponding political interest in global economic stability; and the emergence of a global managerial culture focused on performance, quality, and service. Professor Zipkin goes on to say 'In Supply Chain Structures, the editors Jeannette Song and David Yao have collected a spectrum of approaches to these challenges from some of the leading scholars of supply chains, from both the academic and commercial worlds. Each of the articles offers an interesting and illuminating way to think about the key issues in supply chain management. Some also offer practical techniques to solve important problems. Together they provide an excellent survey of the current state of the art in research and practice.' 460 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -RF CMOS Power Amplifiers: Theory Design and Implementation focuses on the design procedure and the testing issues of CMOS RF power amplifiers. This is the first monograph addressing RF CMOS power amplifier design for emerging wireless standards. The focus on power amplifiers for short is distance wireless personal and local area networks (PAN and LAN), however the design techniques are also applicable to emerging wide area networks (WAN) infrastructure using micro or pico cell networks. The book discusses CMOS power amplifier design principles and theory and describes the architectures and tardeoffs in designing linear and nonlinear power amplifiers. It then details design examples of RF CMOS power amplifiers for short distance wireless applications (e, g., Bluetooth, WLAN) including designs for multi-standard platforms. Design aspects of RF circuits in deep submicron CMOS are also discussed. RF CMOS Power Amplifiers: Theory Design and Implementation serves as a reference for RF IC design engineers and RD and R&D managers in industry, and for graduate students conducting research in wireless semiconductor IC design in general and with CMOS technology in particular. 116 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides a collection of theoretical articles and empirical studies on innovation and location by focusing on the institutions and systems that mediate knowledge spillovers. The objective is to provide an international comparison using a variety of approaches. The volume is organized around the three themes. The first focuses on theoretical work that attempts to advance our understanding of knowledge externalities and systems on innovation. The second section provides empirical studies that attempt to measure these impacts. The final section considers future challenges to regional economic development policy in the face of economic integration and globalization. 388 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Considerably simplified models of macroscopic material behavior, such as the idealization for metals of elastic-time independent plastic response with a yield (onset) criterion, have served the engineering profession well for many years. They are still basic to the design and analysis of most structural applications. In the need to use materials more effectively, there are circumstances where those traditional models are not adequate, and constitutive laws that are more physically realistic have to be employed. This is especially relevant to conditions where the inherent time dependence of inelastic deformations, referred to as 'viscoplasticity', is pronounced such as at elevated temperatures and for high strain rates. Unified theories of elastic-viscoplastic material behavior, which are primarily applicable for metals and metallic alloys, combine all aspects of inelastic response into a set of time dependent equations with a single inelastic strain rate variable. For such theories, creep under constant stress, stress relaxation under constant strain, and stress-strain relations at constant rates are each special cases of a general formulation. Those equations mayor may not include a yield criterion, but models which do not separate a fully elastic region from the overall response could be considered 'unified' in a more general sense. The theories have reached a level of development and maturity where they are being used in a number of sophisticated engineering applications. However, they have not yet become a standard method of material representation for general engineering practice. 132 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Scan 2000, the GAMM - IMACS International Symposium on Scientific Computing, Computer Arithmetic, and Validated Numerics and Interval 2000, the International Conference on Interval Methods in Science and Engineering were jointly held in Karlsruhe, September 19-22, 2000. The joint conference continued the series of 7 previous Scan-symposia under the joint sponsorship of GAMM and IMACS. These conferences have traditionally covered the numerical and algorithmic aspects of scientific computing, with a strong emphasis on validation and verification of computed results as well as on arithmetic, programming, and algorithmic tools for this purpose. The conference further continued the series of 4 former Interval conferences focusing on interval methods and their application in science and engineering. The objectives are to propagate current applications and research as well as to promote a greater understanding and increased awareness of the subject matters. The symposium was held in Karlsruhe the European cradle of interval arithmetic and self-validating numerics and attracted 193 researchers from 33 countries. 12 invited and 153 contributed talks were given. But not only the quantity was overwhelming we were deeply impressed by the emerging maturity of our discipline. There were many talks discussing a wide variety of serious applications stretching all parts of mathematical modelling. New efficient, publicly available or even commercial tools were proposed or presented, and also foundations of the theory of intervals and reliable computations were considerably strengthened. 412 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Queueing is an aspect of modern life that we encounter at every step in our daily activities. Whether it happens at the checkout counter in the supermarket or in accessing the Internet, the basic phenomenon of queueing arises whenever a shared facility needs to be accessed for service by a ]arge number of jobs or customers. The study of queueing is important as it gravides both a theoretical background to the kind of service that we may expect from such a facility and the way in which the facility itself may be designed to provide some specified grade of service to its customers. Our study of queueing was basically motivated by its use in the study of communication systems and computer networks. The various computers, routers and switches in such a network may be modelled as individual queues. The whole system may itself be modelled as a queueing network providing the required service to the messages, packets or cells that need to be carried. Application of queueing theory provides the theoretical framework for the design and study of such networks. The purpose of this book is to support a course on queueing systems at the senior undergraduate or graduate Ievels. Such a course would then provide the theoretical background on which a subsequent course on the performance modeHing and analysis of computer networks may be based. 312 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Creating Internet Intelligence is an interdisciplinary treatise exploring the hypothesis that global computer and communication networks will one day evolve into an autonomous intelligent system, and making specific recommendations as to what engineers and scientists can do today to encourage and shape this evolution. A general theory of intelligent systems is described, based on the author's previous work; and in this context, the specific notion of Internet intelligence is fleshed out, in its commercial, social, psychological, computer-science, philosophical, and theological aspects. Software engineering work carried out by the author and his team over the last few years, aimed at seeding the emergence of Internet intelligence, is reviewed in some detail, including the Webmind AI Engine, a uniquely powerful Internet-based digital intelligence, and the Webworld platform for peer-to-peer distributed cognition and artificial life. The book should be of interest to computer scientists, philosophers, and social scientists, and more generally to anyone concerned about the nature of the mind, or the evolution of computer and Internet technology and its effect on human life. 356 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Two ofthe most important notions concerning the rights of people with mental illness are among the most neglected: the first is that human rights and duties are complementary and that both must be considered in constructing a framework for mental health care. The second is that we must strive for equity and not only for equality in developing mental health programs. The first ofthese notions is complex. It refers to the duties ofpeople with mental illness and to the duties ofthose who surround them. Mental illness does not liberate the person who has it from civic obligations. The most basic ofthese is to give support to others and to refuse to harm them Their carers, society and the patient's self-respect all gain through their recognition, even though the fulfilment of these obligations might be difficult or impossible in certain periods ofillness. The duty of those surrounding the patients is to recognise and respect their existence and to make the necessary arrangements to respond to their needs, protect their rights and compensate for their temporary or permanent inability to fulfil their civic duties. A society's social capital is the public good that results from the mutual supportofmembers ofa society: iffor one reason or another, some or all members ofa society fail to offer such support the social capital will diminish and the society will cease to be civic. 248 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since the appearance of the John O'Keefe and Lynn Nadel book in which they proposed that the hippocampus provides an abstract, internal representation of the animal's environment, considerable conceptual progress in the area of navigational information processing has been achieved. The purpose of the current work is to consolidate recent data and conceptual insights related to navigational insight processing in a format useful to both practitioners and advanced students in neuroscience. 280 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Extractions of Metals from Soils and Waters represents a new emphasis in the series Modern Inorganic Chemistry, namely the impact inorganic chemistry can have on the environment. Also, this is the first volume ever to introduce the reader to all aspects of heavy metal extraction. While the primary emphasis is on complexation chemistry, attention is also paid to phase transfer aspects. Particular methods of note include electrokinetics, phytoremediation, and sensors. Aimed primarily at chemists, this book will also appeal to engineers, plant biochemists, environmental health specialists, and practitioners or students of environmental law. 396 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Free energy calculations represent the most accurate computational method available for predicting enzyme inhibitor binding affinities. Advances in computer power in the 1990s enabled the practical application of these calculations in rationale drug design. This book represents the first comprehensive review of this growing area of research and covers the basic theory underlying the method, numerous state of the art strategies designed to improve throughput and dozen examples wherein free energy calculations were used to design and evaluate potential drug candidates. 420 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Advances in molecular biology and recombinant DNA technology have accelerated progress in many fields of life science research, including gene therapy. A large number of genetic engineering approaches and methods are readily available for gene cloning and therapeutic vector construction. Significant progress is being made in genomic, DNA sequencing, gene expression, gene delivery and cloning. Thus gene therapy has already shown that it holds great promise for the treatment of many diseases and disorders. In general it involves the delivery of recombinant genes or transgenes into somatic cells to replace proteins with a genetic defect or to transfer with the pathological process of an illness. The viral and non-viral delivery systems may hold the potential for future non-invasive, cost-effective oral therapy of genetically-based disorders. Recent years have seen considerable progress in the discovery and early clinical development of a variety of gene therapeutic products. The availability, validation, and implementation of gene therapeutic products has also enabled success in testing and evaluation. New challenges will need to be overcome to ensure that products will also be successful in later clinical development and ultimately for marketing authorisation. These new challenges will include improvements in delivery systems, better control of in-vivo targeting, increased level transduction and duration of expression of the gene, and manufacturing process efficiencies that enable reduction in production costs. Perhaps profound understanding of regulated gene design may result in innovative bioproducts exhibiting safety and efficacy profiles that are significantly superior to those achieved by the use of naturally occurring genes. This procedure may contribute considerably to fulfilling standards set by regulatory authorities. This book provides an overview of the current advances in the field of gene therapy and the methods that are being successfully applied in the manufacture of gene therapeutic products, and hopefully will stimulate further progress and advancement in this field to meet the ever-increasing demands. 372 pp. Englisch.