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B N Sahu

Published by Today and Tomorrows, New Delhi (1983)

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Hardcover

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From: Vedams eBooks (P) Ltd (New Delhi, India)

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About this Item: Today and Tomorrows, New Delhi, 1983. Hardbound. Condition: As New. New. Contents Foreword. Preface. I. Pharmacognosy 1. Variation in Alkaloid content. 2. The pharmacognosy of Rauvolfia roots. 3. Alkaloids from Rauvolfia species. 4. Synonyms of Rauvolfia alkaloids. II. Biogenesis of Rauvolfia Alkaloids 5. Biogenesis of Rauvolfia alkaloids. III. Extraction purification and structure elucidation of Rauvolfia alkaloids 6. Extraction of Rauvolfia alkaloids. 7. Estimation of reserpine in pharmaceutical products. 8. Purification of Rauvolfia alkaloids. 9. Identification structure elucidation and stereochemistry of Rauvolfia alkaloids. 10. Classification of Rauvolfia Alkaloids. IV. Chemistry of Rauvolfia alkaloids 11. Chemistry of Rauvolfia alkaloids. V. Chemistry of reserpine group 12. Plant sources isolation and properties of reserpine group alkaloids. 13. Structure elucidation and chemistry of reserpine group. 14. Modification of reserpine skeleton. 15. Synthetic preparation of reserpine. 16. Crude Rauvolfia extracts. 17. Reserpine cogeners. 18. Reserpine analogs. VI. Pharmacology of Rauvolfia Alkaloids. 19. Pharmacology of Rauvolfia Alkaloids. 20. Pharmacodynamics of reserpine. 21. Metabolism excretion and mode of action of reserpine serpentine and rescinnamine. 22. Therapeutic and bio assay of Rauvolfia preparation. 23. Rauvolfia preparations. 24. The drug of commerce. 25. Side effect of Rauvolfia drugs. 26. Rauvolfia Serpentina Benth in Ayurvedic Unani and home medicine. Author index. Subject index. Primitive man sought out and put an extraordinary value on plants that had sundry psychic effect. He concluded also that psychoactive plants were the abode of divinities or supernatural forces. Such plant species are Rauvolfia Serpentina and Rauvolfia conescens of India Rauvolfia Vomitoria of Africa and Rauvolfia heterophylla of Central South Africa Mexico and West Indies. Present knowledge of the chemistry of the so called divinity containing plants indicates the presence of more than thirty two alkaloids some flavonoid compounds terpene sterols and sugars. The various character of these natural products and their assemblage pose fundamental questions to the scientists. All accomplishments achieved in respect of the plant have been well exemplified in this volume. The subject matter of the volume has been divided into six parts. Part I deals with Pharmacognosy of Rauvolfia roots necessary for detection of adulteration. Part II deals with Biogenesis of Rauvolfia alkaloids. Part III relates to extraction isolation and identification of alkaloids and determination of reserpine content in tablets Elixir triturations and separation and purification structure elucidation and stereo chemistry of Rauvolfia alkaloids flavonoid compounds terpenes and sterols. Part IV deals with chemistry of Rauvolfia alkaloids. The alkaloids have been classified on the biogenesis basis. Plant sources extraction properties and structure elucidation of each alkaloid has been indicated. Part V deals with the chemistry of reserpine group. Plant sources structure absolute configuration synthetic preparation of reserpine reserpine cogenors and reserpine analogs have been discussed in detail. Part VI relates to pharmacology of Rauvolfia alkaloids. Sources of drugs (Pharmacognosy) their action and fate in animal and human system (Pharmacodynamics) their use in treatment of disorders (Therapeutics) and their poisonous effect (toxicology) Chemotherapy of drugs and doses of medicine (Posology of Rauvolfia preparations have been indicated in brief. A large number of selected references are listed at the end of each chapter to support descriptions and to direct interested workers towards wide reading and to pursue selectively those of greatest value. Illustrations form an important part of a Book in organic chemistry A combination of adequacy and balance of illustrative materials has been the goal. Attempt has been made to deal with Rauvolfia alkaloids within the cover of a single volume like that of Vinca Alkaloids Catharanthus alkaloids and. Seller Inventory # 56736

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Himadri Panda

Published by Discovery (2017)

ISBN 10: 9350568330 ISBN 13: 9789350568330

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From: Vedams eBooks (P) Ltd (New Delhi, India)

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About this Item: Discovery, 2017. Hardcover. Condition: New. 1st Edition. Contents: Preface. 1. Introduction. 2. Cultivation. 3. Psychophilous mode of pollination. 4. Analysis of hairy root culture of Rauvolfia serpentine. 5. Physiological, biochemical and modern biotechnological approach to improvement of rauwolfia serpentine. 6. Pharmacognostical profiling on the root of rauwolfia serpentina. 7. Phyto-pharmacognostical studies and quantitative determination of reserpine in different parts of Rauwolfia. 8. Extraction and Evaluation of Indole Alkaloids from Rauwolfia serpentina for their antimicrobial and antimicrobial and antiproliferative activities. 9. Floral and reproductive biology of Sarpagandha Rauvolfia serpentine. 10. Rauwolfia (Reserpine) as a potential antihypertensive agent. 11. Indole alkaloids from “Hairy roots” of rauwolfia serpentine. 12. Antibacterial effect of Rauwolfia serpentina. 13. Antioxidant status of rauwolfia serpentina. 14. Anti-venom activity of ethanolic extract of Rauwolfia Serpentine against Naja Naja (Cobra) Venom. 15. Rauwolfia serpentina ameliorates hyperglycemic, haematinic and antioxidant status in alloxan-induced diabetic mice. 16. Production of secondary metabolites from in vitro cultures of Rauwolfia serpentine (L.) Benth. 17. Application of HPTLC in standardisation of homoeopathic mother tincture Rauwolfia serpentina and its comparison with products in market. 18. Method for treating hypertension with methylreserpate. 19. Method for promoting hair growth and improving hair and scalp health. 20. Method of assisting weight loss. 21. Antitumor and antiviral medications. 22. Beta-glucosidase and a process for extraction. 23. Use of ACE inhibitors for treatment of patients suffering from behavioral disorders. 24. Sleep inducing antacid composition. 25. Bio-reactor for enhancing the biomass yield of plant organs. 26. Substituted lactams useful as Angiotensin converting enzyme inhibitors. 27. Orally administered anti-stress composition. 28. Substituted enantholactam derivatives as antihypertensives. 29. Composition of rapid disintegrating direct compression buccal tablet. 30. Fused tricyclic lactams as angiotensin converting enzyme inhibitors and as antihypertensive agents. 31. Benzofused lactams as antihypertensives. References. Index. Sophisticated advancements in chemistry combined with changing pattern of consumer preference have revolutionized the chemical maneuvering of medicinal herbs. Semi purified/purified chemical derivatives of herbs like extracts, fractionates, isolates are being preferred over the whole herb for therapeutic uses. As a logical spin off, this also has thrown up a debate, if these chemical derivatives are medicinally better than the herb. In addition to the classical support for the use of whole herb, many recent research findings also indicate that extracts are always not necessarily better medicinal substance than the whole herb as in case of root of Sarpagandha (Rauvolfia) ‘serpentine’ herb and its alkaloid reserpine agement of hypertension and other CNS diseases. Sarpagandha (Rauvolfia serpentina) is a species of flowering plant in the family Apocynaceae. About 80 alkaloids are isolated from Rauvolfia species among them reserpine is most important principal active constituent. The authors suggest, it is prudent to use the whole herb for therapeutic applications, until and unless any chemical derivative is proved to be better than the whole herb. The authors do recognize the importance of chemical standardization of the herbs for quality assurance and strongly advocates for it. Finally, the objective of this article is not to show the extracts in a poorer light, but to critically evaluate the trend of chemically purifying herbs. Unfortunately, owing to lack of such assessments, extraction has become a fashion in herbal industry rather than a justified requirement. So the author compiled all the important scattered findings on this plant and accommodate in the form of a manuscripts, so that students,research scholars and scientists r. Seller Inventory # 119754

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