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The molecular configuration of deoxyribonucleic acid (2 parts). Inscribed by Wilkins & Langridge

Wilkins, Langridge et al.

Publication Date: 1960
Soft cover
From Jeremy Norman's historyofscience (Novato, CA, U.S.A.)

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Inscribed by Langridge and Wilkins Langridge, Robert (1933- ); Wilson, H. R. (1929- ); Hooper, C. W.; Wilkins, Maurice (1916- ); and Hamilton, L. D. The molecular configuration of deoxyribonucleic acid. I. X-ray diffraction study of a crystalline form of the lithium salt. Offprint from J. Molecular Biol. 2 (1960). 20pp. Plate, text illustrations. With: Langridge, Robert (1933- ); Marvin, D. A.; Seeds, W. E.; Wilson, H. R. (1929- ); Hooper, C. W.; Wilkins, Maurice (1916- ); and Hamilton, L. D. The molecular configuration of deoxyribonucleic acid. II. Molecular models and their Fourier transforms. Offprint from J. Molecular Biol. 2 (1960). [1], 38-64pp. Plate, text illustrations. Together 2 items. 254 x 172 mm. Original printed self-wrappers. Fine copies, inscribed by Langridge ("Regards, Bob") and Wilkins ("M. H. F. Wilkins") on the front wrappers. First Separate Editions. The first part of this paper presents an analysis of the x-ray diffraction patterns given by the lithium salt of DNA (LiDNA), "from which it may be deduced that the DNA molecule is helical with pitch 34 , probably contains two polynucleotide chains, and that each chain contains 10 nucleotides per turn. This configuration is known as the B type and exists in unfixed cell nuclei" (p. 2). The second part contains a correction of the Watson-Crick DNA molecular model based on calculations of the Fourier transform of DNA's molecular structure. An appendix to this part, by Langridge and two co-authors, describes how the Fourier transforms were calculated using an IBM 650 digital computer. Langridge, who obtained his doctorate in crystallography from the University of London under Maurice Wilkins's supervision, was the first to apply a stored program digital computer to the analysis of DNA structure, as described in his PhD. thesis (1957). Bookseller Inventory # 38474

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Title: The molecular configuration of ...

Publication Date: 1960

Binding: Soft cover

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