Inscribed Presentation Copy Malassez, Louis-Charles (1842-1909). De la numeration des globules rouges du sang. 74pp. Paris: Adrien Delahaye, 1873. Text illustrations. 253 x 165 mm. (uncut and unopened). Original printed wrappers, minor wear and chipping at extremities, ownership inscription ("Martin") on front wrapper. Light foxing but very good. Presentation Copy, inscribed by Malassez to "Martin" on the title: "A mon collègue et ami Martin [. . .] de la Charité, L. Malassez." First Edition. Malassez, a pupil of Claude Bernard, invented the hemocytometer, a device originally designed to count red blood cells; it is now used to count other types of cells as well. He first described the hemocytometer in the present paper, which was published a year before the journal article cited in Garrison-Morton (no. 876). The instrument, illustrated on page 24, consists of a thick glass microscope slide with a rectangular indentation that creates a chamber; this chamber is engraved with a grid of perpendicular lines. The area bounded by the lines is known and the depth of the chamber is also known; it is therefore possible to count the number of cells in a given volume of fluid, and thus to determine the concentration of cells in the fluid overall. Malassez's treatise also contains the first published description of the diluting pipette invented in 1867 by his colleague Pierre Potain (1825-1901); an illustration of this device is on page 13. These two inventions led to greater facility in counting both red and white blood cells.This was the trade edition Malassez's thesis; a thesis edition was published in Paris by A. Parent, also in 1873. Garrison-Morton (online) 876. Histoire illustrée de l'hématologie, pp. 20, 36. Wintrobe, Hematology: The Blossoming of a Science, p. 52. Bookseller Inventory # 43171
Title: De la numeration des globes rouges du sang
Publisher: A. Delahaye
Publication Date: 1873
Binding: Soft cover
Edition: 1st Edition
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