Signal Transduction Pathways in Autoimmunity (Current Directions in Autoimmunity, Vol. 5)

0 avg rating
( 0 ratings by Goodreads )
 
9783805573085: Signal Transduction Pathways in Autoimmunity (Current Directions in Autoimmunity, Vol. 5)
View all copies of this ISBN edition:
 
 

An immensely complex network of interactions between multiple cell types and cytokines regulates the immune system. Ligand binding to antigen-specific, Fc, or cytokine receptors initiates differentiation, activation and proliferation of multiple immune system cell lineages. These activating pathways are counteracted by inhibitory receptors. In the past two decades, considerable work on mechanistic and functional details of such intracellular signaling pathways has led to the realization that an excess of stimulatory/positive signals as well as a deficiency in inhibitory/negative signals can both result in a hyperactive immune system leading to autoimmunity. The chapters included in this volume represent but a few examples of the close link between aberrant signaling pathways and autoimmune diseases. They cover a variety of cells (T, B and myeloid/monocytic cells), receptors (for antigen, Fc and cytokines) and intracellular signaling molecules (kinases, phosphatases, adapters and transcription factors) in the immune system. This book brings together clinical and experimental aspects of autoimmune disease and the fundamental science of intracellular signaling pathways. Therefore, it should be of interest to clinical investigators of autoimmune diseases as well as to basic immunologists and cell biologists interested in the molecular basis of signal transduction in the immune system.

"synopsis" may belong to another edition of this title.

Buy Used
Zustand: in gebrauchtem, gutem... Learn more about this copy

Shipping: US$ 16.60
From Germany to U.S.A.

Destination, rates & speeds

Add to Basket

Top Search Results from the AbeBooks Marketplace

Stock Image

1.

Altman A
ISBN 10: 3805573081 ISBN 13: 9783805573085
Used Hardcover Quantity Available: 1
Seller:
Antiquariat BuchX
(Eurasburg, Germany)

Book Description Zustand: in gebrauchtem, gutem Zustand, aus Privatbesitz, geringe Lese- Lagerspuren, Altersgemaesse kleinere Maengel sind nicht immer extra aufgefuehrt., Rechnung mit ausgewiesener MwSt.(ISBN 3805573081), Verlag: Karger, S, Ausgabe von 2002-01-01, Einband: Gebundene Ausgabe, Seiten: 198 , Gewicht 590 g. Seller Inventory # E1707691

More information about this seller | Contact this seller

Buy Used
US$ 234.59
Convert currency

Add to Basket

Shipping: US$ 16.60
From Germany to U.S.A.
Destination, rates & speeds