Calcium Regulation of Cellular Function (Volume 30) (Advances in Second Messenger and Phosphoprotein Research, Volume 30) - Hardcover

Hardcover

ISBN 10: 0120361302 ISBN 13: 9780120361304

Publisher: Academic Press, 1998

Synopsis

Volume 30 examines the prominent role of calcium as an intracellular second messenger. Leading investigators review a wide variety of studies on how calcium enters and moves through cells, how it interacts with its many binding proteins, and how calcium and its intracellular receptor, calmodulin, control vital cellular processes. Coverage includes a detailed analysis of the mechanisms by which calcium bound to calmodulin regulates contractile proteins in smooth muscle cells. Close attention is given to the roles of calcium and calmodulin-dependent protein kinases and phosphatases in synaptic signal transduction, protein synthesis, gene expression, programmed cell death, activation of T-lymphocytes, and control of cell division cycles. Other chapters discuss studies using genetically manipulable nonmammalian organisms to further proble the functions of calcium and calmodulin.

About this title

About the Author:

Angus C. Nairn is currently Associate Professor at The Rockefeller University. He has published a large number of papers concerned with the structure and regulation of protein kinases and phosphatases involved in signal transduction, particularly with respect to signalling by calcium.

About this edition

• Publisher: Academic Press
• Publication date: 1998
• ISBN 10: 0120361302
• ISBN 13: 9780120361304
• Binding: Hardcover
• Edition number: 1
• Number of pages: 416
• Editor: Means Anthony R.