Intracellular Protein Degradation (In Focus Series) - Softcover

Doherty, Fergus J.; Mayer, R. John

9780199632930: Intracellular Protein Degradation (In Focus Series)

Softcover

ISBN 10: 0199632936 ISBN 13: 9780199632930

Publisher: Oxford University Press, 1992

Intracellular protein degradation is becoming an area of widely increasing research. It is central to both normal cellular homeostasis and chronic degenerative and viral diseases. Many of the currently incompletely understood human diseases are in fact protein catabolic disorders of some sort. This important book describes the mechanisms of intracellular protein degradation at the molecular and cell biological levels. Topics include the kinetics of protein degradation, lysosomes, cystosolic proteases, the ubiquitin pathway, molecular determinants of protein half-line, and protein degradation in disease. The book will be invaluable to researchers and students in biochemistry, cell biology, and medicine.

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About the Author:

R. John Mayer, Professor of Molecular and Cell Biology, both at the Department of Biochemistry, University of Nottingham Medical School, Queen's Medical Centre.

Review:

'The text is a pleasure to read; references are up to date ... This is an ideal book for investigators ... this is an interesting and timely resource which gives a wealth of information for its approximately 60 pages.'
Anne Cress, Arizona Health Sciences Center, Trends in Cell Biology, Vol. 3, May 1993

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