The Electroencephalogram: Its Patterns and Origins - Hardcover

Barlow, John S.

9780262023542: The Electroencephalogram: Its Patterns and Origins

Hardcover

ISBN 10: 0262023547 ISBN 13: 9780262023542

Publisher: Bradford Books, 1993

Although the electroencephalogram - discovered more than a century ago - has been used for years as a non-invasive diagnostic tool, it is still poorly understood. In this book, John Barlow describes an ingenious new hypothesis for a comprehensive model of the EEG that is able to emulate a large variety of known EEG patterns with few variables.In contrast to previous hypotheses and models which have treated only selected EEG patterns (rhythmic activity such as alpha activity and sleep spindles seen largely as "filtered noise," or irregular activity, or certain types of epileptiform activity such as spikes) this approach, which is based on an oscillator with two separate input modulations of the extremes and the slopes of waves, covers all types of EEG patterns, and stems from specific features of the EEG itself rather than from arbitrary signals.Barlow describes the hypothesis in detail, then tests predictions for normal and abnormal EEGs with the aid of a hardware model and with specially developed methods of analysis. The hypothesis is further evaluated in the light of extensive reviews of other EEG models and methods of analysis and of the underlying anatomy, physiology, and pathophysiology of cerebral electrical activity. A technological section details the hardware model and the methodology for testing the hypothesis. Appendixes present some new approaches to traditional methods of EEG analysis and artifact minimization, areas in which Barlow has achieved international recognition.John S. Barlow, M.D., is a Neurophysiologist in the Neurology Service at Massachusetts General Hospital, Senior Research Associate in Neurology (Neurophysiology) at Harvard Medical School, and a Research Affiliate in the Research Laboratory of Electronics at the Massachusetts Institute of Technology.

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About the Author:

John S. Barlow, M.D., is a Neurophysiologist in the Neurology Service at Massachusetts General Hospital, Senior Research Associate in Neurology (Neurophysiology) at Harvard Medical School, and a Research Affiliate in the Research Laboratory of Electronics at the Massachusetts Institute of Technology.

Review:

Doctor Barlow is a pioneer in the field of computer analysis of the electroencephalogram and is internationally recognized as a leading authority on advanced techniques of data processing and data analysis as applied to electrophysiology. At the same time, he is recognized as an authority in clinical electroencephalography. Because of these outstanding qualifications, a book by Doctor Barlow is one that anyone interested in information processing in the central nervous system would eagerly look forward to reading. The book is well written and can be appreciated by readers with several different levels of expertise and backgrounds- an important contribution, stimulating and thought provoking.

(Donald W. Klass, M.D., Professor of Neurology, Senior Consultant, Electroencephalography, Mayo Foundation and Mayo Graduate School of Medicine)

Certaintly there is a paucity of models of brain waves and a serious need for them. Barlow's model is very ingenious and surprising in its ability to emulate a variety of known EEG patterns with so few variables. It is a significant contribution to the science.

(Theodore Bullock, Department of Neuroscience, School of Medicine, University of California, San Diego)

This is a major contribution, highly original and provacative.

(Charles E. Henry, Ph.D., Professor of Neurology, Medical College of Virginia)

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