Cellular Mechanotransduction: Diverse Perspectives from Molecules to Tissues - Hardcover

Hardcover

ISBN 10: 0521895235 ISBN 13: 9780521895231

Publisher: Cambridge University Press, 2009

Synopsis

"Mechanotransduction" is the term for the ability, first described by 19th-century anatomist Julius Wolff, of living tissues to sense mechanical stress and respond by tissue remodeling. More recently, the scope of mechanotransduction has been expanded to include the sensation of stress, its translation into a biochemical signal, and the sequence of biological responses it produces. This book looks at mechanotransduction in a more restricted sense, focusing on the process of stress sensing and transducing a mechanical force into a cascade of biochemical signals. This stress has become increasingly recognized as one of the primary and essential factors controlling biological functions, ultimately affecting the function of the cells, tissues, and organs. A primary goal of this broad book is also to help define the new field of mechanomics, which attempts to describe the complete mechanical state of a biological system.

About this title

Book Description:

Living tissues sense mechanical stress and respond by tissue remodeling and by sending biochemical signals that produce a sequence of biological responses. This book focuses on the process of stress sensing and transducing mechanical force into biochemical signals. It helps define mechanomics, which describes the mechanical state of a biological system.

About the Author:

Dr Mohammad Reza Kaazempur Mofrad is currently Assistant Professor of Bioengineering at the University of California, Berkeley, where he is also an affiliated faculty member of graduate programs in applied science and technology, biophysics, computational biology and genomics, and bioengineering (UCSF-Berkeley). Dr Mofrad received his B.A.Sc. degree from Sharif University of Technology in Tehran, Iran. After earning M.A.Sc. and Ph.D. degrees from the Universities of Waterloo and Toronto, respectively, he spent two years at MIT and Harvard Medical School/Massachusetts General Hospital as a post-doctoral Fellow. Before joining the faculty at Berkeley, Dr Mofrad was a Principal Research Scientist at MIT for nearly two years. At Berkeley, he has developed and taught several courses, namely Cell Mechanics and Mechanotransduction, Introductory Biomechanics, Molecular Cell Biomechanics, and Biological Transport Phenomena.

About this edition

• Publisher: Cambridge University Press
• Publication date: 2009
• ISBN 10: 0521895235
• ISBN 13: 9780521895231
• Binding: Hardcover
• Edition number: 1
• Number of pages: 465
• Editor: Mofrad Mohammad R. K., Kamm Roger D.