From The New England Journal of Medicine:
The field of hematology is growing increasingly complex, especially in the area of hemostatic and thrombotic disorders. Paradoxically, however, the number of practicing clinical hematologists in the United States has been static or has even decreased. Many physicians who practice hematology, both those in the community and those in academia, are combining their practice with that of medical oncology, thereby diluting their clinical experience and scope of reading. For these reasons, Consultative Hemostasis and Thrombosis fills an important niche. It will be a valuable resource for the busy general hematologist and for the busy internist who finds it increasingly difficult to obtain expert hematologic consultation. In his thoughtful introductory chapter on the consultative process, Dr. Kitchens quotes Will Rogers: "Everyone is ignorant, only on different subjects." This book is designed to reduce some of that ignorance by covering a broad range of subjects in the field of hemostasis and thrombosis. It is organized into six sections. Part I includes an introduction to the consultative process, laboratory testing, and the overall approach to the patient with bleeding. Part II covers various conditions leading to bleeding: hemophilia, von Willebrand's disease, immune thrombocytopenic purpura, disseminated intravascular coagulation, and platelet dysfunction. Part III deals with thrombotic processes, including deep venous thrombosis, thrombotic thrombocytopenic purpura, and the antiphospholipid antibody syndrome. I was delighted to find whole chapters on subjects that are all too often a subheading in larger textbooks, including venous thrombosis at unusual sites and the postphlebitic syndrome. This section also demonstrates the increasing overlap between hematology and cardiovascular medicine, with two chapters on arterial thrombosis. Part IV is called, a little misleadingly, "Pharmacologic Agents." It certainly deals with the usual anticoagulants and antifibrinolytic agents but also includes some succinct information on transfusion. A brief, but valuable, final chapter deals with topical hematostatic agents. The last two sections of the book cover special areas. Problems specific to women are covered in chapters on the thrombotic risks of contraceptive and postmenopausal hormone therapy. The authors of this chapter did not have the final results of the Women's Health Initiative available, but the discussion presages its conclusions. Other chapters cover bleeding disorders and thrombophilic states in pregnancy. Part VI includes what the editors call "special considerations" and covers a diverse range of topics from outpatient anticoagulant therapy to hemostasis and thrombosis in the intensive care unit. In addition, the editors have selected some very important areas in which the hematologist is often expected to be an expert, including vena cava filters and neuraxial anesthesia. Cover to cover, this book is well under 700 pages, yet it is comprehensive. Space is well used, with many clear tables. Within the individual chapters, all graphs and diagrams are in black and white, but there are four pages of helpful color plates. In addition to medical aspects, many chapters have sections on the consultative process, as well as brief sections on cost containment and medicolegal issues, where appropriate. I was puzzled to find a detailed discussion of anticoagulant reversal in the chapter on transfusion. It would have been much more appropriate to include this section in the chapter on anticoagulants, where readers would certainly expect to find it. In a rapidly changing field, it is inevitable that new information will become available after the chapters of a book have been written, but before the book is published. This is particularly true in the case of anticoagulation therapy, with the intensive search for better anticoagulants than warfarin and heparin. Since the chapter on anticoagulation is certainly the one in this book that will become outdated most rapidly, it would have been helpful to include preliminary information about the use of the synthetic pentasaccharides and oral direct thrombin inhibitors. However, these are minor criticisms of a book I believe will have an important place in the practice of hematology. Drs. Kitchens, Alving, and Kessler have selected an excellent group of contributors, each recognized as an expert in his or her field. Equally important, the editors have selected a fascinating and unusually comprehensive range of topics for the practicing hematologist and the interested generalist. Even as I was reviewing this book, I found myself consulting it with regard to current clinical problems in my own practice, and I expect to continue using it frequently and enthusiastically until the next edition is published. Cynthia J. Rutherford, M.B., Ch.B.
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