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Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can mean that different individuals respond differently to the same drug or chemical.
Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. An international team of experts consider the interplay between epigenetics and toxicology in a number of areas, including environmental, nutritional, pharmacological, and computational toxicology, nanomaterials, proteomics and metabolomics, and cancer research.
Topics covered include:
- environment, epigenetics and diseases
- DNA methylation and toxicogenomics
- chromatin at the intersection of disease and therapy
- epigenomic actions of environmental arsenicals
- environment, epigenetics and cardiovascular health
- toxicology, epigenetics and autoimmunity
- ocular epigenomics: potential sites of environmental impact in development and disease
- nuclear RNA silencing and related phenomena in animals
- epigenomics – impact for drug safety sciences
- methods of global epigenomic profiling
- transcriptomics: applications in epigenetic toxicology
Toxicology and Epigenetics is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors and regulators in academia, industry and government.
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About the Author:
Review:
Dr. Saura C. Sahu, Research Chemist, Division of Toxicology, Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, US Food and Drug Administration.
Dr. Sahu is the US Editor for the Journal of Applied Toxicology and the editor of Hepatotoxicity (Wiley, 2007), Toxicogenomics (Wiley, 2008), Nanotoxicity (Wiley, 2009), and Handbook of Systems Toxicology (Wiley, 2011).
“Despite some of the issues with the structure, Toxicology and Epigenetics is an important, timely book that provides world-class, expert opinion on a broad range of topics in a fast moving highly relevant branch of toxicology.” (British Toxicology Society, 1 July 2013)
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- PublisherWiley
- Publication date2012
- ISBN 10 111997609X
- ISBN 13 9781119976097
- BindingHardcover
- Edition number1
- Number of pages688
- EditorSahu Saura C.
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Book Description Hardcover. Condition: new. Hardcover. Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can mean that different individuals respond differently to the same drug or chemical. Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. An international team of experts consider the interplay between epigenetics and toxicology in a number of areas, including environmental, nutritional, pharmacological, and computational toxicology, nanomaterials, proteomics and metabolomics, and cancer research. Topics covered include: environment, epigenetics and diseasesDNA methylation and toxicogenomicschromatin at the intersection of disease and therapyepigenomic actions of environmental arsenicalsenvironment, epigenetics and cardiovascular healthtoxicology, epigenetics and autoimmunityocular epigenomics: potential sites of environmental impact in development and diseasenuclear RNA silencing and related phenomena in animalsepigenomics impact for drug safety sciencesmethods of global epigenomic profilingtranscriptomics: applications in epigenetic toxicology Toxicology and Epigenetics is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors and regulators in academia, industry and government. This book describes cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Seller Inventory # 9781119976097
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Book Description Condition: New. This book describes cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. Editor(s): Sahu, Saura C. Num Pages: 688 pages, Illustrations. BIC Classification: PSAK; PSBT. Category: (P) Professional & Vocational. Dimension: 250 x 194 x 35. Weight in Grams: 1310. . 2012. . . . . Seller Inventory # V9781119976097
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Toxicology and Epigenetics (Hardcover)
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Book Description Hardcover. Condition: new. Hardcover. Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can mean that different individuals respond differently to the same drug or chemical. Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. An international team of experts consider the interplay between epigenetics and toxicology in a number of areas, including environmental, nutritional, pharmacological, and computational toxicology, nanomaterials, proteomics and metabolomics, and cancer research. Topics covered include: environment, epigenetics and diseasesDNA methylation and toxicogenomicschromatin at the intersection of disease and therapyepigenomic actions of environmental arsenicalsenvironment, epigenetics and cardiovascular healthtoxicology, epigenetics and autoimmunityocular epigenomics: potential sites of environmental impact in development and diseasenuclear RNA silencing and related phenomena in animalsepigenomics impact for drug safety sciencesmethods of global epigenomic profilingtranscriptomics: applications in epigenetic toxicology Toxicology and Epigenetics is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors and regulators in academia, industry and government. This book describes cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Seller Inventory # 9781119976097
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Book Description Hardcover. Condition: new. Hardcover. Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can mean that different individuals respond differently to the same drug or chemical. Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. An international team of experts consider the interplay between epigenetics and toxicology in a number of areas, including environmental, nutritional, pharmacological, and computational toxicology, nanomaterials, proteomics and metabolomics, and cancer research. Topics covered include: environment, epigenetics and diseasesDNA methylation and toxicogenomicschromatin at the intersection of disease and therapyepigenomic actions of environmental arsenicalsenvironment, epigenetics and cardiovascular healthtoxicology, epigenetics and autoimmunityocular epigenomics: potential sites of environmental impact in development and diseasenuclear RNA silencing and related phenomena in animalsepigenomics impact for drug safety sciencesmethods of global epigenomic profilingtranscriptomics: applications in epigenetic toxicology Toxicology and Epigenetics is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors and regulators in academia, industry and government. This book describes cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. Seller Inventory # 9781119976097
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Toxicology and Epigenetics
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Book Description Condition: New. This book describes cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. Editor(s): Sahu, Saura C. Num Pages: 688 pages, Illustrations. BIC Classification: PSAK; PSBT. Category: (P) Professional & Vocational. Dimension: 250 x 194 x 35. Weight in Grams: 1310. . 2012. . . . . Books ship from the US and Ireland. Seller Inventory # V9781119976097
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