Items related to Biology and Regulation of Blood-Tissue Barriers (Advances...

Biology and Regulation of Blood-Tissue Barriers (Advances in Experimental Medicine and Biology, 763) - Hardcover

 
9781461447108: Biology and Regulation of Blood-Tissue Barriers (Advances in Experimental Medicine and Biology, 763)
View all copies of this ISBN edition:
 
 
This book was written by many outstanding investigators who have spent decades to study different aspects of blood-tissue barrier function. They have summarized some of the latest and fascinating development in their fields of research including the blood-brain barrier, the blood-retinal barrier, the gut barrier, the blood-biliary barrier, the blood-follicle barrier, the blood-epididymis barrier, the blood-testis barrier, the tight junction barrier in general as well as barriers in the female reproductive tract. Included are also chapters that focus on topics that are physiologically applicable to all blood-tissue barriers. Many of these chapters also include information on specific human diseases, such as pathological changes of the gut barrier that cause bowel disorders resulting from inflammation of the epithelial lining in the intestine, and infertility in men as a result of disruption of the blood-epididymal and/or blood-testis barriers; and on new therapeutic approaches (e.g., drug delivery across the blood-brain and the blood-retinal barriers).

"synopsis" may belong to another edition of this title.

From the Back Cover:
.
About the Author:

Dr. C. Yan Cheng is a native of Hong Kong and a graduate from the Chinese University of Hong Kong in 1977. Shortly after receiving his BSc, he began his graduate training in the laboratory of Professor Barry Boettcher at the University of Newcastle, New South Wales, Australia and received his PhD in 1981. He joined the laboratory of Dr. C. Wayne Bardin as a postdoctoral fellow, working with him and Drs. Neal A. Musto and Glen Gunsalus at the Population Council’s Center for Biomedical Research located on the campus of the Rockefeller University in New York City for a little over 4 years. During this period, he had the opportunity to interact with a number of eminent scientists and visiting scientists who were at the Population Council including Drs. Jennie Mather, Vilma Rossi, and Geoffrey Hammond. Dr. Bardin had also created an unprecedented stimulating and competitive environment that shaped his career in life sciences. Through his collaboration with Dr. Vilma Rossi, he met Professor Bruno Silvestrini in the summer of 1985 in New York, and began a scientific collaboration that spans more than two decades to develop new derivatives of indazole-carboxylic acid for male contraception with the development of adjudin, 1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide, as a potential male contraception. He has also used different animal models, such as the adjudin model, the cadmium model, the bisphenol A model and a few genetic models to study different aspects of testicular function in particular the biology and regulation of cell adhesion in the testis. Through this work, he and his colleagues, Drs. Helen Yan, Elissa Wong, Will Lee and Dolores Mruk, have discovered a functional axis that links the different cellular compartments in the seminiferous epithelium of the testis known as the apical ectoplasmic specialization-blood-testis barrier-hemidesmosome/basement membrane axis that coordinates different cellular events during the seminiferous epithelial cycle of spermatogenesis. They have also identified several putative signaling pathways and nonreceptor protein kinases, such as focal adhesion kinase (FAK ) and members of the c-Src kinases, that regulate blood-testis barrier dynamics. Some of these findings are currently under development to design innovative compounds for male contraception. For the past three decades, his laboratory has received supports from the Angelini Research Institute, Rockefeller Foundation, Lupus Foundation of America, CONRAD Program, USAID, and the National Institutes of Health. He has published over 300 research articles and reviews in peer-reviewed journals in the field. He is currently a Senior Scientist and the Head of the Mary M. Wohlford Laboratory for Male Contraceptive Research at the Population Council’s Center for Biomedical Research in New York City.

1H-indazole-3-carbohydrazide, as a potential male contraception. He has also used different animal models, such as the adjudin model, the cadmium model, the bisphenol A model and a few genetic models to study different aspects of testicular function in particular the biology and regulation of cell adhesion in the testis. Through this work, he and his colleagues, Drs. Helen Yan, Elissa Wong, Will Lee and Dolores Mruk, have discovered a functional axis that links the different cellular compartments in the seminiferous epithelium of the testis known as the apical ectoplasmic specialization-blood-testis barrier-hemidesmosome/basement membrane axis that coordinates different cellular events during the seminiferous epithelial cycle of spermatogenesis. They have also identified several putative signaling pathways and nonreceptor protein kinases, such as focal adhesion kinase (FAK ) and members of the c-Src kinases, that regulate blood-testis barrier dynamics. Some of these findings are currently under development to design innovative compounds for male contraception. For the past three decades, his laboratory has received supports from the Angelini Research Institute, Rockefeller Foundation, Lupus Foundation of America, CONRAD Program, USAID, and the National Institutes of Health. He has published over 300 research articles and reviews in peer-reviewed journals in the field. He is currently a Senior Scientist and the Head of the Mary M. Wohlford Laboratory for Male Contraceptive Research at the Population Council’s Center for Biomedical Research in New York City.

"About this title" may belong to another edition of this title.

  • PublisherSpringer
  • Publication date2012
  • ISBN 10 1461447100
  • ISBN 13 9781461447108
  • BindingHardcover
  • Number of pages381
  • EditorCheng C. Yan

Top Search Results from the AbeBooks Marketplace

Stock Image

Cheng, C. Yan
Published by Springer (2012)
ISBN 10: 1461447100 ISBN 13: 9781461447108
New Hardcover Quantity: 1
Seller:
Front Cover Books
(Denver, CO, U.S.A.)

Book Description Condition: new. Seller Inventory # FrontCover1461447100

More information about this seller | Contact seller

Buy New
US$ 126.98
Convert currency

Add to Basket

Shipping: US$ 4.30
Within U.S.A.
Destination, rates & speeds
Stock Image

Cheng, C. Yan
Published by Springer (2012)
ISBN 10: 1461447100 ISBN 13: 9781461447108
New Hardcover Quantity: 1
Seller:
Wizard Books
(Long Beach, CA, U.S.A.)

Book Description Hardcover. Condition: new. New. Seller Inventory # Wizard1461447100

More information about this seller | Contact seller

Buy New
US$ 128.26
Convert currency

Add to Basket

Shipping: US$ 3.50
Within U.S.A.
Destination, rates & speeds
Stock Image

Cheng, C. Yan
Published by Springer (2012)
ISBN 10: 1461447100 ISBN 13: 9781461447108
New Hardcover Quantity: 1
Seller:
GoldBooks
(Austin, TX, U.S.A.)

Book Description Hardcover. Condition: new. New Copy. Customer Service Guaranteed. Seller Inventory # think1461447100

More information about this seller | Contact seller

Buy New
US$ 134.24
Convert currency

Add to Basket

Shipping: US$ 4.25
Within U.S.A.
Destination, rates & speeds
Seller Image

Published by Springer (2012)
ISBN 10: 1461447100 ISBN 13: 9781461447108
New Hardcover Quantity: 10
Print on Demand
Seller:
booksXpress
(Bayonne, NJ, U.S.A.)

Book Description Hardcover. Condition: new. This item is printed on demand. Seller Inventory # 9781461447108

More information about this seller | Contact seller

Buy New
US$ 168.61
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds
Stock Image

Published by Springer (2012)
ISBN 10: 1461447100 ISBN 13: 9781461447108
New Hardcover Quantity: > 20
Seller:
Lucky's Textbooks
(Dallas, TX, U.S.A.)

Book Description Condition: New. Seller Inventory # ABLIING23Mar2716030036525

More information about this seller | Contact seller

Buy New
US$ 179.00
Convert currency

Add to Basket

Shipping: US$ 3.99
Within U.S.A.
Destination, rates & speeds
Stock Image

C. Yan Cheng
Published by Springer (2012)
ISBN 10: 1461447100 ISBN 13: 9781461447108
New Hardcover Quantity: > 20
Print on Demand
Seller:
Ria Christie Collections
(Uxbridge, United Kingdom)

Book Description Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. Seller Inventory # ria9781461447108_lsuk

More information about this seller | Contact seller

Buy New
US$ 181.05
Convert currency

Add to Basket

Shipping: US$ 12.59
From United Kingdom to U.S.A.
Destination, rates & speeds
Seller Image

C Yan Cheng
Published by SPRINGER NATURE Sep 2012 (2012)
ISBN 10: 1461447100 ISBN 13: 9781461447108
New Hardcover Quantity: 2
Print on Demand
Seller:
BuchWeltWeit Ludwig Meier e.K.
(Bergisch Gladbach, Germany)

Book Description Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book was written by many outstanding investigators who have spent decades to study different aspects of blood tissue barrier function. They have summarized some of the latest and fascinating development in their fields of research including the blood brain barrier, the blood retinal barrier, the gut barrier, the blood biliary barrier, the blood follicle barrier, the blood epididymis barrier, the blood testis barrier, the tight junction barrier in general as well as barriers in the female reproductive tract. Included are also chapters that focus on topics that are physiologically applicable to all blood tissue barriers. Many of these chapters also include information on specific human diseases, such as pathological changes of the gut barrier that cause bowel disorders resulting from inflammation of the epithelial lining in the intestine, and infertility in men as a result of disruption of the blood epididymal and/or blood testis barriers; and on new therapeutic approaches (e.g., drug delivery across the blood brain and the blood retinal barriers). 361 pp. Englisch. Seller Inventory # 9781461447108

More information about this seller | Contact seller

Buy New
US$ 178.74
Convert currency

Add to Basket

Shipping: US$ 24.87
From Germany to U.S.A.
Destination, rates & speeds
Seller Image

Cheng, C. Yan
Published by Springer New York (2012)
ISBN 10: 1461447100 ISBN 13: 9781461447108
New Hardcover Quantity: > 20
Print on Demand
Seller:
moluna
(Greven, Germany)

Book Description Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Written by outstanding investigators in their fields Covers some of the more interesting aspects of research in blood-tissue barriers Focuses on topics that are physiologically applicable to all blood-tissue barriersWritten by ou. Seller Inventory # 458500284

More information about this seller | Contact seller

Buy New
US$ 158.69
Convert currency

Add to Basket

Shipping: US$ 52.97
From Germany to U.S.A.
Destination, rates & speeds
Seller Image

C Yan Cheng
Published by Springer Nature Singapore (2012)
ISBN 10: 1461447100 ISBN 13: 9781461447108
New Hardcover Quantity: 2
Seller:
AHA-BUCH GmbH
(Einbeck, Germany)

Book Description Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book was written by many outstanding investigators who have spent decades to study different aspects of blood tissue barrier function. They have summarized some of the latest and fascinating development in their fields of research including the blood brain barrier, the blood retinal barrier, the gut barrier, the blood biliary barrier, the blood follicle barrier, the blood epididymis barrier, the blood testis barrier, the tight junction barrier in general as well as barriers in the female reproductive tract. Included are also chapters that focus on topics that are physiologically applicable to all blood tissue barriers. Many of these chapters also include information on specific human diseases, such as pathological changes of the gut barrier that cause bowel disorders resulting from inflammation of the epithelial lining in the intestine, and infertility in men as a result of disruption of the blood epididymal and/or blood testis barriers; and on new therapeutic approaches (e.g., drug delivery across the blood brain and the blood retinal barriers). Seller Inventory # 9781461447108

More information about this seller | Contact seller

Buy New
US$ 182.68
Convert currency

Add to Basket

Shipping: US$ 35.67
From Germany to U.S.A.
Destination, rates & speeds
Stock Image

Published by Springer (2012)
ISBN 10: 1461447100 ISBN 13: 9781461447108
New Hardcover Quantity: 4
Seller:
Books Puddle
(New York, NY, U.S.A.)

Book Description Condition: New. pp. xx + 361 1st Edition. Seller Inventory # 2658567698

More information about this seller | Contact seller

Buy New
US$ 412.18
Convert currency

Add to Basket

Shipping: US$ 3.99
Within U.S.A.
Destination, rates & speeds

There are more copies of this book

View all search results for this book