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Molecular Aspects of Early Development ISBN 13: 9781468446302

Molecular Aspects of Early Development - Softcover

 
9781468446302: Molecular Aspects of Early Development
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The early embryo has emerged as the focal point for analysis of the regulation of gene expression for several reasons. First, the fact that embryogenesis is under genetic control has been appreciated from the earliest days of classical embryology. When experimental techniques became available it was therefore logical that they should be applied to the embryo. With each new advance in methodology, interest in embryonic gene expression studies has increased. Second, many embryos offer unique opportunities for the investigation of specific aspects of the regulation of gene expression. Several phenomena--eg. , control of translation--can be very conveniently studied in a variety of marine invertebrate embryos. Those embryos contain large stores of maternally inherited mRNA which are translated in a highly ordered fashion during specific stages of post fertilization development. Marine invertebrate eggs can be conveniently artifically inseminated and labeled with radioactive precursors. Their analysis is leading to important insights into the mechanisms which regulate gene expression at post-transcriptional levels. Third, recent advances in both transmission and recombinant DNA genetics, especially in organisms such as Drosophila, are providing special opportunities for the analysis of regulatory mechanisms which operate at the level of the genome. Specific genes have been identified, isolated, and--in some instances--sequenced. The opportunity is now available to study the regulation of the expression of single genes in a vertical fashion--from the primary sequence of the gene to the tissues and organs which are the products of morphogenesis.

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  • PublisherSpringer
  • Publication date2012
  • ISBN 10 1468446304
  • ISBN 13 9781468446302
  • BindingPaperback
  • Number of pages332
  • EditorMalacinski George M.

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Book Description Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - The early embryo has emerged as the focal point for analysis of the regulation of gene expression for several reasons. First, the fact that embryogenesis is under genetic control has been appreciated from the earliest days of classical embryology. When experimental techniques became available it was therefore logical that they should be applied to the embryo. With each new advance in methodology, interest in embryonic gene expression studies has increased. Second, many embryos offer unique opportunities for the investigation of specific aspects of the regulation of gene expression. Several phenomena--eg. , control of translation--can be very conveniently studied in a variety of marine invertebrate embryos. Those embryos contain large stores of maternally inherited mRNA which are translated in a highly ordered fashion during specific stages of post fertilization development. Marine invertebrate eggs can be conveniently artifically inseminated and labeled with radioactive precursors. Their analysis is leading to important insights into the mechanisms which regulate gene expression at post-transcriptional levels. Third, recent advances in both transmission and recombinant DNA genetics, especially in organisms such as Drosophila, are providing special opportunities for the analysis of regulatory mechanisms which operate at the level of the genome. Specific genes have been identified, isolated, and--in some instances--sequenced. The opportunity is now available to study the regulation of the expression of single genes in a vertical fashion--from the primary sequence of the gene to the tissues and organs which are the products of morphogenesis. Seller Inventory # 9781468446302

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Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The early embryo has emerged as the focal point for analysis of the regulation of gene expression for several reasons. First, the fact that embryogenesis is under genetic control has been appreciated from the earliest days of classical embryology. When experimental techniques became available it was therefore logical that they should be applied to the embryo. With each new advance in methodology, interest in embryonic gene expression studies has increased. Second, many embryos offer unique opportunities for the investigation of specific aspects of the regulation of gene expression. Several phenomena--eg. , control of translation--can be very conveniently studied in a variety of marine invertebrate embryos. Those embryos contain large stores of maternally inherited mRNA which are translated in a highly ordered fashion during specific stages of post fertilization development. Marine invertebrate eggs can be conveniently artifically inseminated and labeled with radioactive precursors. Their analysis is leading to important insights into the mechanisms which regulate gene expression at post-transcriptional levels. Third, recent advances in both transmission and recombinant DNA genetics, especially in organisms such as Drosophila, are providing special opportunities for the analysis of regulatory mechanisms which operate at the level of the genome. Specific genes have been identified, isolated, and--in some instances--sequenced. The opportunity is now available to study the regulation of the expression of single genes in a vertical fashion--from the primary sequence of the gene to the tissues and organs which are the products of morphogenesis. 336 pp. Englisch. Seller Inventory # 9781468446302

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