Items related to Investigation on CYP2C19 and Clopidogrel in Bangladeshi...
Investigation on CYP2C19 and Clopidogrel in Bangladeshi Population: The first Clinical study on CYP2C19 and the effect of Clopidogrel in different variants of Bangladeshi Population - Softcover
The aim of this study was to investigate the allelic distribution of CYP219 genes in Bangladeshi population by using PCR–RFLP method and then the effect of Clopidogrel on Prothrombin Time in different variants of CYP2C19. For genotyping of CYP2C19 alleles blood samples were collected from fifty healthy adult Bangladeshi volunteers. DNA was extracted and PCR-RFLP analysis was employed to genotype CYP2C19*2 and CYP2C19*3. PCR products were digested by Sma I and Bam HI respectively. In case of CYP2C19*2, there were 82% wild variants, 12% heterozygote and 6% mutant variants and in case of CYP2C19*3 there were 98% wild or normal homozygote and 2% heterozygote but there were no mutant variant in our study. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular diseases. Prothombin Time (PT) and International Normalized Ratio (INR) were measured four hours after Clopidogrel 75 mg ingestion. We found increased PT and INR in Homozygote and Heterozygote variants but the statistically significant (P> 0.05) variation was found only in case of Homozygote variants. In case of mutant, we did not find any variation in PT and INR.
"synopsis" may belong to another edition of this title.
About the Author:
Muhammad Shahdaat Bin Sayeed obtained B.Pharm from University of Dhaka. He is National Coordinator of Bangladesh for International Brain Bee. Dr. Abul Hasnat supervised current research on Prothrombin Time variation due to Clopidogrel in different variant of CYP2C19 of Bangladeshi population.
"About this title" may belong to another edition of this title.
- PublisherLAP LAMBERT Academic Publishing
- Publication date2012
- ISBN 10 3845403403
- ISBN 13 9783845403403
- BindingPaperback
- Number of pages172
Buy New
Learn more about this copy
US$ 69.55
Shipping:
US$ 3.99
Within U.S.A.
Top Search Results from the AbeBooks Marketplace
Stock Image
Investigation on CYP2C19 and Clopidogrel in Bangladeshi Population: The first Clinical study on CYP2C19 and the effect of Clopidogrel in different variants of Bangladeshi Population
Published by
LAP LAMBERT Academic Publishing
(2012)
ISBN 10: 3845403403
ISBN 13: 9783845403403
New
Softcover
Quantity: > 20
Seller:
Rating
Book Description Condition: New. Seller Inventory # ABLIING23Apr0316110111617
Buy New
US$ 69.55
Convert currency
Stock Image
Investigation on CYP2C19 and Clopidogrel in Bangladeshi Population
Published by
LAP Lambert Academic Publishing
(2012)
ISBN 10: 3845403403
ISBN 13: 9783845403403
New
Softcover
Quantity: > 20
Seller:
Rating
Book Description Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. Seller Inventory # ria9783845403403_lsuk
Buy New
US$ 78.23
Convert currency
Stock Image
Investigation on CYP2C19 and Clopidogrel in Bangladeshi Population
Published by
LAP Lambert Academic Publishing 2012-04
(2012)
ISBN 10: 3845403403
ISBN 13: 9783845403403
New
PF
Quantity: 10
Seller:
Rating
Book Description PF. Condition: New. Seller Inventory # 6666-IUK-9783845403403
Buy New
US$ 72.65
Convert currency
Stock Image
Investigation on CYP2C19 and Clopidogrel in Bangladeshi Population The first Clinical study on CYP2C19 and the effect of Clopidogrel in different variants of Bangladeshi Population
Published by
LAP LAMBERT Academic Publishing
(2012)
ISBN 10: 3845403403
ISBN 13: 9783845403403
New
PAP
Quantity: > 20
Seller:
Rating
Book Description PAP. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Seller Inventory # L0-9783845403403
Buy New
US$ 96.95
Convert currency
Seller Image
Investigation on CYP2C19 and Clopidogrel in Bangladeshi Population
Published by
LAP Lambert Academic Publishing Apr 2012
(2012)
ISBN 10: 3845403403
ISBN 13: 9783845403403
New
Taschenbuch
Quantity: 2
Seller:
Rating
Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aim of this study was to investigate the allelic distribution of CYP219 genes in Bangladeshi population by using PCR-RFLP method and then the effect of Clopidogrel on Prothrombin Time in different variants of CYP2C19. For genotyping of CYP2C19 alleles blood samples were collected from fifty healthy adult Bangladeshi volunteers. DNA was extracted and PCR-RFLP analysis was employed to genotype CYP2C19\*2 and CYP2C19\*3. PCR products were digested by Sma I and Bam HI respectively. In case of CYP2C19\*2, there were 82% wild variants, 12% heterozygote and 6% mutant variants and in case of CYP2C19\*3 there were 98% wild or normal homozygote and 2% heterozygote but there were no mutant variant in our study. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular diseases. Prothombin Time (PT) and International Normalized Ratio (INR) were measured four hours after Clopidogrel 75 mg ingestion. We found increased PT and INR in Homozygote and Heterozygote variants but the statistically significant (P> 0.05) variation was found only in case of Homozygote variants. In case of mutant, we did not find any variation in PT and INR. 172 pp. Englisch. Seller Inventory # 9783845403403
Buy New
US$ 74.55
Convert currency
Seller Image
Investigation on CYP2C19 and Clopidogrel in Bangladeshi Population : The first Clinical study on CYP2C19 and the effect of Clopidogrel in different variants of Bangladeshi Population
Published by
LAP Lambert Academic Publishing
(2012)
ISBN 10: 3845403403
ISBN 13: 9783845403403
New
Taschenbuch
Quantity: 1
Seller:
Rating
Book Description Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The aim of this study was to investigate the allelic distribution of CYP219 genes in Bangladeshi population by using PCR-RFLP method and then the effect of Clopidogrel on Prothrombin Time in different variants of CYP2C19. For genotyping of CYP2C19 alleles blood samples were collected from fifty healthy adult Bangladeshi volunteers. DNA was extracted and PCR-RFLP analysis was employed to genotype CYP2C19\*2 and CYP2C19\*3. PCR products were digested by Sma I and Bam HI respectively. In case of CYP2C19\*2, there were 82% wild variants, 12% heterozygote and 6% mutant variants and in case of CYP2C19\*3 there were 98% wild or normal homozygote and 2% heterozygote but there were no mutant variant in our study. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular diseases. Prothombin Time (PT) and International Normalized Ratio (INR) were measured four hours after Clopidogrel 75 mg ingestion. We found increased PT and INR in Homozygote and Heterozygote variants but the statistically significant (P> 0.05) variation was found only in case of Homozygote variants. In case of mutant, we did not find any variation in PT and INR. Seller Inventory # 9783845403403
Buy New
US$ 74.55
Convert currency
Stock Image
Investigation on CYP2C19 and Clopidogrel in Bangladeshi Population The first Clinical study on CYP2C19 and the effect of Clopidogrel in different variants of Bangladeshi Population
Published by
LAP LAMBERT Academic Publishing
(2012)
ISBN 10: 3845403403
ISBN 13: 9783845403403
New
PAP
Quantity: > 20
Seller:
Rating
Book Description PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Seller Inventory # L0-9783845403403
Buy New
US$ 79.56
Convert currency
Seller Image
Investigation on CYP2C19 and Clopidogrel in Bangladeshi Population
Published by
LAP LAMBERT Academic Publishing
(2012)
ISBN 10: 3845403403
ISBN 13: 9783845403403
New
Softcover
Quantity: > 20
Seller:
Rating
Book Description Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Bin Sayeed Muhammad ShahdaatMuhammad Shahdaat Bin Sayeed obtained B.Pharm from University of Dhaka. He is National Coordinator of Bangladesh for International Brain Bee. Dr. Abul Hasnat supervised current research on Prothrombin Time. Seller Inventory # 5480496
Buy New
US$ 60.53
Convert currency