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In vitro cytotoxicity evaluation on hydroxyapatite base material: Value added bone replacement material


ISBN 10: 3639236327 / ISBN 13: 9783639236323
Published by VDM Verlag Dr. Müller, 2010
Condition: Good Soft cover
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Title: In vitro cytotoxicity evaluation on ...

Publisher: VDM Verlag Dr. Müller

Publication Date: 2010

Binding: Paperback

Book Condition:Good

About this title


Hydroxyapatite (HA) has been used clinically for the last 30 years in medicine and dentistry because of its excellent biocompatibility, osseoconduction and osseointergration. The only problem with pure HA is brittle. Because of this many modifications have been done by scientists to develop a stronger and biocompatible ceramic material especially for bone replacement. Our stronger value added HA has been developed for biocompatibility testing which is cytotoxicity test. In this study we tested this valued added HA for its cytotoxicity against lung embryonic fibroblast cell line (MRC-5).We found that value added HA slightly toxic compared to pure HA. Several recommendations for the scientists and clinicians for the future biocompatibility studies should be further carried out.Truly.

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