Signal Transduction, 2 e, is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. Signal Transduction, 2 e, serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields.
* Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention
* In-depth coverage of nuclear receptors, including steps in isolation of steroid hormones and the discovery of intracellular hormone receptors; tyrosine protein kinases and adaptive immunity; and intracellular calcium
* Extensive conceptual color artwork to assist with comprehension of key topics
* Instrumental margin notes highlight milestones in signaling mechanisms
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A reference on cellular-signalling processes,Signal Transductionsecond edition details the sources, key observations, and experiments that set the scene for recent and current scientific endeavor. Beginning with a historical overview, this book discusses how the concept of chemical messengers arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, and growth factors.
Signal Transductionsecond edition further examines more complex signalling cascades, emanating from classic receptors, as well as adhesion molecules, involved in processes such as vision, smell, inflammation, innate and adaptive immunity, glucose homeostasis, cell-fate decisions, cell differentiation, and cell transformation. This timely revision concludes with a discourse on the targeting of signal-transduction cascades in the treatment of cancer and the structure of protein domains key to the assembly of signalling complexes.About the Author:
Bastien Gomperts, University College, London, United Kingdom
Ijsbrand M Kramer, University of Bordeaux, Talence, France
Peter E.R. Tatham, University College, London, United Kingdom
"About this title" may belong to another edition of this title.
Book Description Elsevier Science & Technology Books. Book Condition: Brand New. Bookseller Inventory # 39661596
Book Description Academic Press, 2009. Book Condition: New. Brand New, Unread Copy in Perfect Condition. A+ Customer Service! Summary: The 2e of the popular and essential text on cell signaling processes. Bookseller Inventory # ABE_book_new_0123694418
Book Description Academic Press, 2009. Hardcover. Book Condition: New. 2. Bookseller Inventory # DADAX0123694418
Book Description Academic Press, 2009. Hardcover. Book Condition: New. book. Bookseller Inventory # 0123694418
Book Description Academic Press, 2015. Hardcover. Book Condition: New. Bookseller Inventory # P110123694418