Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors (Volume 95) (International Review of Neurobiology, Volume 95) - Hardcover
Volume 95 of International Review of Neurobiology focuses on Catechol-O-methyltransferase inhibition, and its clinical application in relation to Parkinson’s disease. Chapters cover COMT gene and proteins, L-dopa treatment in Parkinson’s disease, the latest research on COMT inhibitors and their clinical applications, as well as future prospects for their use.
- Up-to-date summary of biochemistry and pharmacology of COMT and its inhibitors
- Preclinical models in COMT inhibitor devlopment
- Transgenic COMT mice – latest information summarized
- Chemistry of COMT inhibitors and their design with molecular modelling
- COMT gene and its regulation and relation to dopamine related diseases
- Role of cofactor SAM regulation in relation to homocysteine
- Nonclinical and clinical safety of COMT inhibitors summarized
- Future prospects of COMT inhibitors in Parkinson’s disease
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- PublisherAcademic Press
- Publication date2010
- ISBN 10 0123813263
- ISBN 13 9780123813268
- BindingHardcover
- Edition number1
- Number of pages336
- EditorNissinen Erkki
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Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors
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Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of Its Inhibitors
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Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors
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Elsevier Science
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ISBN 13: 9780123813268
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Book Description Condition: New. Focuses on Catechol-O-methyltransferase inhibition, and its clinical application in relation to Parkinson s disease. This title includes chapters that cover COMT gene and proteins, L-dopa treatment in Parkinson s disease, the latest research on COMT inhibit. Seller Inventory # 594357604
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