Intervening Sequences in Evolution and Development - Hardcover

9780195043372: Intervening Sequences in Evolution and Development

Hardcover

ISBN 10: 0195043375 ISBN 13: 9780195043372

Publisher: Oxford University Press, 1990

Biologists have long been puzzled by the peculiar arrangement of genes on the strands of DNA. Genes are interrupted by non-coding regions--intervening sequences or introns--that function in some developmental systems and probably were involved in the evolution of the earliest genes. However, biologists did not anticipate the existence of introns on either functional or evolutionary grounds, and many questions about them remain unsolved. This research level book is ideal for molecular and developmental biologists, evolutionary biologists, and geneticists. It addresses the wide range of issues in this field, including gene structure in primordial organisms, the relationship between gene and protein structure, and gene regulation via differential RNA processing. The first comprehensive treatment of intervening sequences, this unique treatise brings readers a wealth of previously scattered information in one convenient reference source.

"synopsis" may belong to another edition of this title.

About the Author:

Edwin M. Stone, Research Fellow in Ophthalmology, University of Iowa. Robert D. Schwartz, Professor of Cell Biology, Baylor College of Medicine.

Review:

"Readers of different levels of technical sophistication will prefer different chapters. But there is a great deal in this volume to recommend it to experts and novices alike. It will be a worthwhile addition to the libraries of working molecular geneticists and evolutionary biologists interested in the origins of genomic structure." --BioScience

"This book serves as a good introduction to selected evolutionary and developmental aspects raised by the presence of intervening sequences. Readers interested in an overall picture of the field will find this an accessible entry point." Cell

"The various authors have presented a great deal of detailed information and the result is a valuable source book on exon and intron structure and processing." --Biologist

"Provides a readable summary of the natural history of these systems, which could provide an excellent starting point for the careful study of how gene structure affects the dynamics of evolution." --The Quarterly Review of Biology

"The editors have succeeded admirably. . . .The volume serves as a useful introduction." --American Journal of Human Biology

"The various authors have presented a great deal of detailed information and the result is a valuable source book on exon and intron structure and processing." --Biologist

"The idea that introns were present in protein-coding genes of the common ancestor of all surviving organisms is intriguing and has some evidence. . . . the book is good for what it does." --Evolutionary Theory and Review

"About this title" may belong to another edition of this title.