Austin L. Hughes is at Pennsylvania State University.
"Only during the last decade did molecular evolution finally become capable of studying Darwinian selection. Although the evolution of most nucleotides, at any particular moment, is governed by mutation, drift, and/or purifying selection, still there is plenty of room left for adaptive evolution. Many fascinating discoveries have already been made, and Hughes provides the first comprehensive review. ... The first two chapters provide a non-technical review of sequence analysis and a good exposition of what is certainly true and important in neutralism . . . After this, the exposition moves from balancing selection ... to directional selection acting on individual molecules, to evolution of new molecules and functions and finally to adaptation at the level of the whole genome. One can hardly propose a better structure. A lot of very interesting data are presented in clear and readable way. ... I strongly recommend [this book] to anybody interested in molecular evolution."--
Trends in Genetics"This book is clearly written. The examples given illustrate various aspects of Darwinian positive selection pressure exerted on specific genes. These examples are discussed in sufficient detail to be easily understood by readers not too familiar with the subject. . . .the author has achieved the aim of providing a general biological audience with basic knowledge and up to date facts and opinions about a central aspect of natural selection." --
Genetcis, Selection, Evulution