Introduction to Macromolecular Crystallography, 2nd Edition - Softcover

McPherson

Softcover

ISBN 10: 0470185902 ISBN 13: 9780470185902

Publisher: Wiley-Blackwell, 2009

Synopsis

A comprehensive and approachable introduction to crystallography ― now updated in a valuable new edition

The Second Edition of this well-received book continues to offer the most concise, authoritative, and easy-to-follow introduction to the field of crystallography. Dedicated to providing a complete, basic presentation of the subject that does not assume a background in physics or math, the book's content flows logically from basic principles to methods, such as those for solving phase problems, interpretation of Patterson maps and the difference Fourier method, the fundamental theory of diffraction and the properties of crystals, and applications in determining macromolecular structure.

This new edition includes a vast amount of carefully updated materials, as well as two completely new chapters on recording and compiling X-ray data and growing crystals of proteins and other macromolecules.

Richly illustrated throughout to clarify difficult concepts, this book takes a non-technical approach to crystallography that is ideal for professionals and graduate students in structural biology, biophysics, biochemistry, and molecular biology who are studying the subject for the first time.

About this title

About the Author:

Alexander Mcpherson, PhD, is Professor in the Department of Molecular Biology and Biochemistry at the University of California, Irvine's School of Biological Sciences. The author of six books and 300 papers or reviews, he is widely considered the nation's foremost authority in the field of macromolecular crystallography. For over a decade, he has served as principal instructor of the Cold Spring Harbor Laboratory course inmacromolecular X-ray crystallography, an intensive course for which much of the material in this text was originally conceived.

Review:

"...provides an up-to-date overview of the different phases of drug discovery and preclinical development of experimental cancer principles.” (Drug Discovery & Development, September 2004)

"...benefits source: strong writing and a gifted use of analogy to introduce the abstract issues...perfect for a novice..." (Journal of Chemical Education, Vol. 80, No. 9 September 2003)

"...an excellent introductory text..." (Journal of Proteome Research, Vol. 2, No. 2, March/April 2003)

"...this welcome addition to the introductory crystallographic literature should be well received...recommended..." (Choice, Vol. 40, No. 8, April 2003)

"...an excellent introductory text..." (Journal of Proteome Research, Vol. 2, No. 2, March/April 2003)

"...this welcome addition to the introductory crystallographic literature should be well received...recommended..." (Choice, Vol. 40, No. 8, April 2003)

"...I highly recommend this book...in fact, I foresee it finding its way to the bookshelves of many faculty members, albeit with frequent removal for consultation as an educational tool!" (Clinical Chemistry, Vol. 49, No. 7, 2003)

"...excellent and clear introduction...in an easily readable and conversational style it explains many essential principles and methods very effectively..." (Angewandte Chemie International Edition, Vol 42(37), 2003)

About this edition

• Publisher: Wiley-Blackwell
• Publication date: 2009
• ISBN 10: 0470185902
• ISBN 13: 9780470185902
• Binding: Paperback
• Edition number: 2
• Number of pages: 280