Guide to Techniques in Mouse Development, Part B: Mouse Molecular Genetics (Volume 477) (Methods in Enzymology, Volume 477) - Hardcover

9780123848802: Guide to Techniques in Mouse Development, Part B: Mouse Molecular Genetics (Volume 477) (Methods in Enzymology, Volume 477)
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ISBN 10: 0123848806 ISBN 13: 9780123848802
Publisher: Academic Press, 2010
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This volume comprehensively covers new technologies and methodologies that have appeared for the study of mouse development.
  • Update of volume 225, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993
  • Comprehensively covers:
    • new techniques for the cryopreservation of gametes and embryos
    • production of transgenic and null (knockout) animals (use of ES cells)
    • generation of conditional/inducible mutant animals, use of gene-trap mutagenesis
    • analysis of allele-specific expression, use of new reporter constructs
    • humanizing of transgenic animals
    • transcript profiling of mouse development
    • imaging of mouse development
    • rederivation of animals and use of mouse genomics

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About the Author:
Philippe Soriano,is Professor of Cell, Developmental & Regenerative Biology and Professor of Oncological Sciences, Icahn School of Medicine at Mount Sinai, NY, USA

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