Peroxisomal Disorders and Regulation of Genes (Advances in Experimental Medicine and Biology, 544) - Softcover
In most peroxisomal disorders the nervous system is severely affected which explains the clinical and community burden they represent. This is the first book to focus not only on the mutations causing these inherited illnesses, but also on mechanisms that regulate, suppress or enhance expression of genes and their products (enzymes). Indeed since the success and completion of the Human Genome Project all genes (coding DNA sequences) are known. However, of many, their function, and the role of the gene product has not been determined. An example is X-linked adrenoleukodystrophy, the most frequent peroxisomal disorder. Children are born healthy, but in more than 1 out of 3, demyelination of the brain starts unpredictably and they die in a vegetative state. The gene mutated in most families has been known for 10 years; but the true role of the encoded protein, ALDp, is still speculative; and within the same family, very severe and asymptomatic clinical histories co-exist, unexplained by the mutation.
"synopsis" may belong to another edition of this title.
- PublisherSpringer
- Publication date2012
- ISBN 10 1461347823
- ISBN 13 9781461347828
- BindingPaperback
- Number of pages443
- EditorRoels Frank, Baes Myriam, Delanghe Sylvia
Buy New
Learn more about this copy
US$ 169.85
Shipping:
FREE
Within U.S.A.
Top Search Results from the AbeBooks Marketplace
Seller Image
Peroxisomal Disorders and Regulation of Genes (Advances in Experimental Medicine and Biology) [Paperback ]
Seller:
Rating
Book Description Soft Cover. Condition: new. Seller Inventory # 9781461347828
Buy New
US$ 169.85
Convert currency
Stock Image
Peroxisomal Disorders and Regulation of Genes (Advances in Experimental Medicine and Biology, 544)
Seller:
Rating
Book Description Condition: New. Seller Inventory # ABLIING23Mar2716030031557
Buy New
US$ 178.71
Convert currency
Stock Image
Peroxisomal Disorders and Regulation of Genes
Published by
Springer
(2012)
ISBN 10: 1461347823
ISBN 13: 9781461347828
New
Softcover
Quantity: > 20
Seller:
Rating
Book Description Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. Seller Inventory # ria9781461347828_lsuk
Buy New
US$ 176.83
Convert currency
Seller Image
Peroxisomal Disorders and Regulation of Genes
Published by
Springer US
(2012)
ISBN 10: 1461347823
ISBN 13: 9781461347828
New
Softcover
Quantity: > 20
Seller:
Rating
Book Description Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. In most peroxisomal disorders the nervous system is severely affected which explains the clinical and community burden they represent. This is the first book to focus not only on the mutations causing these inherited illnesses, but also on mechanisms tha. Seller Inventory # 4193027
Buy New
US$ 150.15
Convert currency
Seller Image
Peroxisomal Disorders and Regulation of Genes
Published by
Springer US
(2012)
ISBN 10: 1461347823
ISBN 13: 9781461347828
New
Taschenbuch
Quantity: 1
Seller:
Rating
Book Description Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - In most peroxisomal disorders the nervous system is severely affected which explains the clinical and community burden they represent. This is the first book to focus not only on the mutations causing these inherited illnesses, but also on mechanisms that regulate, suppress or enhance expression of genes and their products (enzymes). Indeed since the success and completion of the Human Genome Project all genes (coding DNA sequences) are known. However, of many, their function, and the role of the gene product has not been determined. An example is X-linked adrenoleukodystrophy, the most frequent peroxisomal disorder. Children are born healthy, but in more than 1 out of 3, demyelination of the brain starts unpredictably and they die in a vegetative state. The gene mutated in most families has been known for 10 years; but the true role of the encoded protein, ALDp, is still speculative; and within the same family, very severe and asymptomatic clinical histories co-exist, unexplained by the mutation. Seller Inventory # 9781461347828
Buy New
US$ 185.57
Convert currency
Seller Image
Peroxisomal Disorders and Regulation of Genes
Published by
Springer US Okt 2012
(2012)
ISBN 10: 1461347823
ISBN 13: 9781461347828
New
Taschenbuch
Quantity: 2
Seller:
Rating
Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In most peroxisomal disorders the nervous system is severely affected which explains the clinical and community burden they represent. This is the first book to focus not only on the mutations causing these inherited illnesses, but also on mechanisms that regulate, suppress or enhance expression of genes and their products (enzymes). Indeed since the success and completion of the Human Genome Project all genes (coding DNA sequences) are known. However, of many, their function, and the role of the gene product has not been determined. An example is X-linked adrenoleukodystrophy, the most frequent peroxisomal disorder. Children are born healthy, but in more than 1 out of 3, demyelination of the brain starts unpredictably and they die in a vegetative state. The gene mutated in most families has been known for 10 years; but the true role of the encoded protein, ALDp, is still speculative; and within the same family, very severe and asymptomatic clinical histories co-exist, unexplained by the mutation. 444 pp. Englisch. Seller Inventory # 9781461347828
Buy New
US$ 224.19
Convert currency