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Published by Morgan & Claypool Life Sciences, 2013
ISBN 10: 1615045848ISBN 13: 9781615045846
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
Book
Condition: New.
Published by Morgan & Claypool Life Sciences, 2013
ISBN 10: 1615045848ISBN 13: 9781615045846
Seller: booksXpress, Bayonne, NJ, U.S.A.
Book Print on Demand
Soft Cover. Condition: new. This item is printed on demand.
Published by Morgan and Claypool Publishers, 2013
ISBN 10: 1615045848ISBN 13: 9781615045846
Seller: PBShop.store US, Wood Dale, IL, U.S.A.
Book Print on Demand
PAP. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Published by Biota Publishing, 2013
ISBN 10: 1615045848ISBN 13: 9781615045846
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Book Print on Demand
Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Published by Biota Publishing 2013-09, 2013
ISBN 10: 1615045848ISBN 13: 9781615045846
Seller: Chiron Media, Wallingford, United Kingdom
Book
PF. Condition: New.
Published by Biota Publishing, 2013
ISBN 10: 1615045848ISBN 13: 9781615045846
Seller: Revaluation Books, Exeter, United Kingdom
Book
Paperback. Condition: Brand New. 122 pages. 9.25x7.50x0.39 inches. In Stock.
Published by Morgan and Claypool Publishers, 2013
ISBN 10: 1615045848ISBN 13: 9781615045846
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
Book Print on Demand
PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Published by Morgan & Claypool Publishers, 2013
ISBN 10: 1615045848ISBN 13: 9781615045846
Seller: THE SAINT BOOKSTORE, Southport, United Kingdom
Book Print on Demand
Paperback / softback. Condition: New. This item is printed on demand. New copy - Usually dispatched within 5-9 working days.
Published by Biota Publishing, 2013
ISBN 10: 1615045848ISBN 13: 9781615045846
Seller: moluna, Greven, Germany
Book Print on Demand
Kartoniert / Broschiert. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Reviews the evidence supporting the concept that intrinsic cell survival programmes can be activated by a variety of mildly noxious stimuli or pharmacologic agents to confer protection against the deleterious effects of ischemia/reperfusion.Klappent.
Published by Biota Publishing, 2013
ISBN 10: 1615045848ISBN 13: 9781615045846
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book Print on Demand
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The major purpose of this book is to review the evidence supporting the concept that intrinsic cell survival programs can be activated by a variety of mildly noxious stimuli or pharmacologic agents to confer protection against the deleterious effects of ischemia/reperfusion (I/R). We begin with a discussion of the concept of hormesis (a term used most extensively in the toxicologic literature which refers to biphasic cellular responses that depend on concentration or intensity of a stimulus), review the seminal studies that led to the discovery of the cardioprotective effects of ischemic preconditioning, and outline its therapeutic potential (Chapter 1). This is followed by a summary of our current understanding of the mechanisms of I/R injury (Chapter 2), as this provides several points of intervention in limiting postischemic tissue injury that may be targeted by the adaptive programs invoked by conditioning stimuli. Chapters 3 and 4 focus on the mechanisms underlying ischemic pre-, post-, and remote conditioning, which establishes the mechanistic rationale for development of pharmacologic conditioning strategies that may mimic the remarkably powerful effects of ischemic conditioning (and are covered in Chapter 5). Lifestyle interventions, including exercise, caloric restriction, and consumption of alcoholic beverages and/or phytochemicals, that may induce hormetic responses will also be reviewed in this chapter. While the promise for conditioning as a therapeutic approach is enormous, there are obstacles to its practical application in patients, which are covered in Chapter 6. The final chapter (Chapter 7) examines the extension of our mechanistic understanding of the signaling pathways invoked by conditioning stimuli into the realm of gene therapy and to the preservation of stem cell viability in the harsh ischemic environment as natural translational outgrowths of preconditioning into therapeutics. Table of Contents: Introduction / Hormesis and Preconditioning Defined / Mechanisms of Ischemia/Reperfusion Injury / Ischemic Preconditioning and Cardioprotection / Clinically Useful Applications of Ischemic Conditioning: Distant Site Ischemic Preconditioning and Ischemic Postconditioning / Cardioprotection Induced by Pharmacologic Conditioning and Lifestyle Interventions that Mimic Preconditioning / Cardiovascular Risk Factors, Tachyphylaxis, and the Efficacy of Pre- and Postconditioning / Logical Extensions of Preconditioning: Gene and Stem Cell Therapy for I/R / Acknowledgments / References.
Published by Morgan & Claypool Life Sciences, 2013
ISBN 10: 1615045848ISBN 13: 9781615045846
Seller: Mispah books, Redhill, SURRE, United Kingdom
Book
Paperback. Condition: Like New. Like New. book.