pan stanford publishing pte ltd singapore (35 results)

Hardcover. Condition: new. Hardcover. At the close of the nineteenth century, we stood on the threshold of one of the greatest periods of science, in which the entire world and understanding of science would be shaken to the core and greatly modified. This explosion of knowledge led ultimately to that same information revolution that we live in today. Planck and Einstein showed that light was not continuous but made of small corpuscles that today we call photons. Einstein changed the understanding of mechanics with his theory of relativity: airplanes became conceivable; radio and television blossomed; and the microelectronics industry, which drives most of modern technology, came into being. New areas of science were greatly expanded and developed, and one of these was quantum mechanics, which is the story to be told here. Yet, the development of quantum mechanics and the leadership of Niels Bohr have distorted the understanding of quantum mechanics in a strange way. There are some who would say that Bohr set back the real understanding of quantum mechanics by half a century. I believe they underestimate his role, and it may be something more like a full century. Whether we call it the Copenhagen interpretation, or the Copenhagen orthodoxy, it is the how for the continuing mysticism provided by Mach that is still remaining in quantum mechanics. It is not the why. Why it perseveres and why it was forced on the field in the first place is an important perception to be studied. In this book, I want to trace the development of quantum mechanics and try to uncover the why. At the close of the nineteenth century, we stood on the threshold of one of the greatest periods of science, in which the entire world and understanding of science would be shaken to the core and greatly modified. This explosion of knowledge led ultimately to that same information revolution that we live in today. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Hardcover. Condition: new. Hardcover. This textbook introduces the general points of view of research methodology in the scientific and engineering fields of studies and presents an overview of the technical and professional communication needed for article publication in journals. It comprises several practice exercises that will give beginners the confidence to move on the communicative activities. Every chapter provides problem sets that will help readers check their understanding of each concept. The book will also help readers formulate specific research topics, research questions, and hypotheses; conduct literature reviews relevant to the research topics; develop applicable research methodologies; and write and present their research outlining the key elements of the proposed projects. It is very useful for students and researchers opting for a course on research methodology and for seminars at undergraduate and graduate levels. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Nanobiotechnology is a new interdisciplinary science with revolutionary perspectives arising from the fact that at nanosize the behaviour and characteristics of matter change with respect to ordinary macroscopic dimensions. Nanotechnology is a new way for producing and getting materials, structures and devices with greatly improved or completely new properties and functionalities. This book provides an introductory overview of the nanobiotechnology world along with a general technical framework about mathematical modelling through which we today study the phenomena of charge transport at the nanometer level. Although it is not a purely mathematics or physics book, it introduces the basic mathematical and physical notions that are important and necessary for theory and applications in nanobiotechnology. Therefore, it can be considered an extended formulary of basic and advanced concepts. It can be the starting point for discussions and insights and can be used for further developments in mathematicalphysical modelling linked to the nanobiotechnology world. The book is dedicated to all those who follow their ideas in life and pursue their choices with determination and firmness, in a free and independent way. This book provides an introductory overview of the global world of nanobiotechnology along with a general technical framework about mathematical modelling through which we today study the phenomena of charge transport at nanometer level. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Paperback. Condition: new. Paperback. In the past two decades, significant advances in magnetic resonance microscopy (MRM) have been made possible by a combination of higher magnetic fields and more robust data acquisition technologies. This technical progress has enabled a shift in MRM applications from basic anatomical investigations to dynamic and functional studies, boosting the use of MRM in biological and life sciences. This book provides a simple introduction to MRM emphasizing practical aspects relevant to high magnetic fields. It focuses on biological applications and presents a number of selected examples of neuroscience applications. The text is mainly intended for those who are beginning research in the field of MRM or are planning to incorporate high-resolution MRI in their neuroscience studies. This book provides a simple introduction to MRM emphasizing practical aspects relevant to high magnetic fields. It focuses on biological applications and presents a number of selected examples of neuroscience applications. The text is mainly intended for those who are beginning research in the field of MRM or are planning to incorporate high-resolution MRI in their neuroscience studies. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Paperback. Condition: new. Paperback. The word titanic reminds one of the majestic ship Titanic and James Camerons epic romance movie Titanicin many cases the film first and the ship next. The Titanic was the worlds largest passenger ship when it entered service, measuring 269 m (882 feet) in length, and the largest man-made moving object on earth. The colossal ship and the epic movie inspired the authors, Susai Rajendran (professor of chemistry) and Gurmeet Singh (a renowned academic administrator and an internationally reputed expert in the field of corrosion science and smart materials) to study why the Titanic collapsed. The main reason seems to be bimetallic corrosion, also known as galvanic corrosion. This book discusses various aspects of galvanic corrosion, namely causes, consequences, methods of control, and case studies. It also reports research on the causes of corrosion of the sunken ship, including microbiologically influenced corrosion (MIC) and metallurgical failure. The book is a great reference for research scholars in the field of corrosion, graduate- and postgraduate-level students, the general public, and marine engineers. This book discusses various aspects of galvanic corrosion, namely causes, consequences, methods of control, and case studies. It also reports research on the causes of corrosion of the sunken ship, including microbiologically influenced corrosion (MIC) and metallurgical failure. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Additive manufacturing has matured from rapid prototyping through the now popular and "maker"-oriented 3D printing, recently commercialized and marketed. The terms describing this technology have changed over time, from "rapid prototyping" to "rapid manufacturing" to "additive manufacturing," which reflects largely a focus on technology.This book discusses the uptake, use, and impact of the additive manufacturing and digital fabrication technology. It augments technical and business-oriented trends with those in product design and design studies. It includes a mix of disciplinary and transdisciplinary trends and is rich in case and design material. The chapters cover a range of design-centered views on additive manufacturing that are rarely addressed in the main conferences and publications, which are still mostly, and importantly, concerned with tools, technologies, and technical development. The chapters also reflect dialogues about transdisciplinarity and the inclusion of domains such as business and aesthetics, narrative, and technology critique. This is a great textbook for graduate students of design, engineering, computer science, marketing, and technology and also for those who are not students but are curious about and interested in what 3D printing really can be used for in the near future. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Despite substantial evidence showing the feasibility of Atomic Force Microscopy (AFM) to identify cells with altered elastic and adhesive properties, the use of this technique as a complementary diagnostic method remains controversial. This book is designed to be a practical textbook that teaches how to assess the mechanical characteristics of living, individual cells by AFM. Following a step-by-step approach, it introduces the methodology of measurements in the case of both determination of elastic properties and quantification of adhesive properties. This book is designed to be a practical textbook that teaches how to assess the mechanical characteristics of living, individual cells by AFM. Following a step-by-step approach, it introduces the methodology of measurements in the case of both determination of elastic properties and quantification of adhesive properties. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. This book focuses on the conventional and emerging applications of radiations, which include radio waves and ultraviolet and gamma radiations. It discusses new techniques in radiation therapy and the effects of ionizing radiations on biological systems. The applications of radiations in the synthesis and use of nanoparticles along with the effects of hypergravity indicate a new trend. The book offers a concise account of the latest studies carried out so far and shows the new initiatives to be undertaken in the field of medicine and biology. It covers the medical use of radiations, such as ferrous sulfatebenzoic acidxylenol orange dosimetry, Co-60 tomotherapy, radio-electro-chemotherapy, and fractional radiotherapy, and radiobiological effects, such as the effects of cell phone radiations on human health parameters and the combined effects of radiations and hypergravity on plants. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. High-resolution x-ray diffraction and scattering is a key tool for structure analysis not only in bulk materials but also at surfaces and buried interfaces from the sub-nanometer range to micrometers. This book offers an overview of diffraction and scattering methods currently available at modern synchrotron sources and illustrates bulk and interface investigations of solid and liquid matter with up-to-date research examples. It presents important characteristics of the sources, experimental set-up, and new detector developments. The book also considers future exploitation of x-ray free electron lasers for diffraction applications. Developments in nature and materials sciences are based on the investigation and understanding of nano-scaled properties of matter. This book presents the developments in X-ray diffraction and scattering methods. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Nanoplasmonics is one of the most important growth areas of this century. It is part of nano-optics and nanophotonics and deals with oscillations of electrons in metallic nanoparticles and nanostructures. Also, it is a multidisciplinary subject covering atomic, molecular, and solid-state physics, as well as much of chemistry. Nanoplasmonics makes it possible to combine the nanoscale properties of smart devices with their optical frequencies of operation.Nanoplasmonics presents, for the first time, both the physical principles and mathematical descriptions of main nanoplasmonic effects that now are scattered over thousands of research articles. Importantly, it contains many methods, accompanied by diagrams, for fast estimations and calculations of main properties of nanoparticles of very different shapes and their clusters. It also presents the most important applications of nanoplasmonics, including in medicine, nanolasers, electronics, perfect lenses, and invisibility cloaks. The nanoplasmonics is part of nano-optics and nanotechnology and deals with oscillation of conduction electrons in nanoparticles and nanostructures. This book comprises theoretical and experimental analysis of plasmonic properties of nanoparticles of different shape and made of different materials. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity analysis. Both ligand-based and structure-based in silico approaches, as reviewed in this book, play important roles for all these applications. Computational chemogenomics is expected to increase the quality and productivity of drug discovery and lead to the discovery of new medicines. This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity analysis. Both ligand-based and structure-based in silico approaches, as reviewed in this book, play important roles for all these applications. Computational chemogenomics is expected to increase the quality and productivity of drug discovery and lead to the discovery of new medicines. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Nanotechnology brings new possibilities for the development of sensors, biosensors, and novel electrochemical bioassays. Nanoscale materials have been extensively used in a wide variety of configurations as electrode surfaces to promote electrochemical reaction, as "wires" to enzymes connecting their redox centers to electrode surface, as nanobarcodes for biomolecules, or as tags to amplify the signal of a biorecognition event.Nanomaterial-based electrochemical sensors have been used in many areas, including cancer diagnostics and the detection of infectious organisms. This book reviews important achievements in the field of nanomaterial-based electrochemical sensors and biosensors. Nanotechnology brings new possibilities for the development of sensors, biosensors, and novel electrochemical bioassays. Nanoscale materials have been extensively used in a wide variety of configurations - as electrode surfaces to promote electrochemical reaction, as "wires" to enzymes connecting their redox centers to electrode surface, as nanobarcodes for biomolecules, or as tags to amplify the signal of a biorecognition event. Nanomaterial-based electrochemical sensors have been used in many areas, including cancer diagnostics and the detection of infectious organisms. This book reviews important achievements in the field of nanomaterial-based electrochemical sensors and biosensors. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Regenerative therapy has rapidly developed as one of the most promising treatments for patients suffering from severe heart failure. Autologous bone marrow-derived cells and cardiac stem cells have been clinically applied for cell injection therapy for heart failure. As a next-generation therapy, tissue-engineered myocardial-patch transplantation has also been started clinically. As further advanced therapy, several researchers have started to fabricate three-dimensional beating myocardial tissues. One of the main problems in myocardial tissue engineering is neovascularization within the tissues during scale-up. Several innovative technologies have been developed to overcome the vascularization problem.This book broadly summarizes myocardial tissue engineering and regenerative medicine, which consists of myocardial cell sources, cell therapy for damaged hearts, and tissue engineering technologies for fabricating beating hearts. With respect to myocardial cell source, it focuses on cardiac cells differentiated from embryonic stem and induced pluripotent stem cells. It describes the remarkable results obtained in the past and the present to control neovascularization and presents the future challenges in myocardial tissue engineering research. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Advanced Nanomaterials for Aerospace Applications has been developed for a community interested in space science and nanotechnology. Scientists and engineers from several NASA field centers and the Jet Propulsion Laboratory, University of Puerto Rico, The Pennsylvania State University, and INFN-Laboratori Nazionali di Frascati, Italy, have joined efforts to discuss the applications of nanomaterials in sensors, atmosphere revitalization in habitable space platforms, life support systems, regenerative fuel cells, lithium-ion batteries, robust lightweight materials, nanoelectronics, and electromagnetic shielding. The book concludes with chapters that discuss bringing NASA-relevant nanotechnology into the classroom and the future directions in nanotechnology research and development at NASA. This book presents the applications of nanomaterials in sensors, life support systems, regenerative fuel cells, lithium-ion batteries, robust light weight materials, nanoelectronics, and electromagnetic shielding. With chapters by experts at the forefront of the field, the book examines recent research, development, and applications of nanomaterials. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Medical device regulation in Asia has gained more importance than ever. Governments and regulatory bodies across the region have put in place new regulatory systems or refined the existing ones. A registered product requires a lot of technical documentation to prove its efficacy, safety, and quality. A smooth and successful registration process demands soft skills for dealing with various key stakeholders in the government, testing centers, and hospitals and among doctors. This handbook covers medical device regulatory systems in different countries, ISO standards for medical devices, clinical trial and regulatory requirements, and documentation for application. It is the first to cover the medical device regulatory affairs in Asia. Each chapter provides substantial background materials relevant to the particular area to have a better understanding of regulatory affairs. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Hardcover. Condition: new. Hardcover. Nanomedicine can take advantage of the recent developments in nanobiotechnology research for the creation of platforms with superior drug carrier capabilities, selective responsiveness to the environment, unique contrast enhancement profiles, and improved accumulation at the disease site. This book provides a broad glimpse of how various dendritic nanomaterials have been designed and used as efficient tools for nanomedicine. It comprises a pedagogic introduction to dendrimers and hyperbranched systems and their classical and accelerated syntheses through cutting-edge methodologies. The chapters on dendronized magnetic nanoparticles as theranostics, dendrimers in theory (molecular simulations), siRNA delivery with dendrimers, and dendrimers for image-guided therapy, combined with chapters focused on specific types of dendrimers or hyperbranched structures, detail the cutting-edge research in nanomedicine. Finally, a detailed chapter on issues related to the pharmacokinetics and biodistribution of dendrimers helps choose the right structures for successful transfer from bench to bedside. This book will appeal to those involved in nanobiotechnology, macromolecular science, cancer therapy, tissue repair, and siRNA delivery research. This book provides a broad glimpse of how various dendritic nanomaterials have been designed and used as efficient tools for nanomedicine. It comprises a pedagogic introduction to dendrimers and hyperbranched systems and their classical and accelerated syntheses through cutting-edge methodologies. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Fluorescence imaging, at macro, micro, and submicro scales, has revolutionized biological science in the past 30 years. Immunolabelling has provided precise targeting of molecules in fixed tissue, while fluorescent proteins have enabled localization in living tissues. Fluorescent indicators enable imaging of dynamic changes in cell metabolism.This book covers, for the first time, imaging at all scales from macro to submicro (superresolution). Its authors include Robert Clegg, legendary teacher and researcher (who, sadly, passed away during the editing); Jim Pawley, editor of several editions of the Handbook of Biological Confocal Microscopy; the famous and now dispersed New Zealand team of Mark Cannell, Christian Soeller, and David Baddeley; Robert Hoffman, pioneer of whole-animal imaging in cancer research; Andreas Schoenle and Christian Eggeling on STED nanoscopy, and many more famous participants in this field. All the contributors are at the cutting edge of their field. Fluorescent indicators enable the imaging of dynamic changes in cell metabolism. This book covers for the first time imaging at all scales, from macro to sub-micro (super-resolution). All the contributors are at the cutting edge of their field. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Hardcover. Condition: new. Hardcover. Research in functional nanomaterials has been expanded exponentially since the turn of the millennium, and these nanomaterials have become more structurally complex in order to achieve the desired properties and functionalities. Scientists had taken ideas from evolution in nature and adapted these ideas for materials synthesis. We also exploit the unique properties of simple molecular systems for making functional nanomaterials. This book offers a comprehensive account on the recent development of several key classes of nanomaterials and their applications in various scientific areas. It summarizes the synthesis, development and characterization for each type of materials. The six chapters start with the simplest "zero"-dimensional nanoparticles and then gradually increase in complexity of the materials towards synthesis using biological templates. Researchers in materials science, nanotechnology and chemistry, especially those interested in functional materials, can use this book as a useful reference. This book offers a comprehensive account on the recent development of several key classes of nanomaterials and their applications in various scientific areas. It summarizes the synthesis, development and characterization for each type of materials. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Hardcover. Condition: new. Hardcover. Bioadhesion is often defined as the state in which two materials, at least one of which is biological in nature, are held together for extended periods of time by interfacial forces. It is an area of active multidisciplinary research, where engineers, scientistsincluding chemists, physicists, biologists, and medical expertsmaterials producers, and manufacturers combine their knowledge. From the practical point of view, bioadhesive systems have been used for several years for medical applications such as dentistry and orthopedics and are now entering new fields, for example, tissue sealing and directed drug delivery systems. Understanding bioadhesion mechanisms is of prime importance while exploring desired adhesion for bioadhesion applications such as sealants as well as successful prevention of undesired adhesion of biomolecules, cells, or organisms. Controlling the occurrence of bioadhesion events is also an important problem in the design and use of medical devices, biosensors, membranes, ships, and oil rigs. This book provides a comprehensive view of bioadhesion and highlights different aspects of this phenomenon. The first section of the book presents fundamentals aspects of bioadhesion. It also summarizes various direct and indirect methods used to investigate and characterize bioadhesion. The second section describes studies of natural adhesives. These include "wet" adhesives that are produced and secreted by sessile marine organisms such as mussels and sand tubes and "dry" adhesives such as the one characterizing the gecko foot. The third section focuses on biomimetic adhesives. These man-made materials are fabricated on the basis of the lessons learned from nature emphasizing the correlation between nature understanding and biomimetics. Finally, the last section reviews medical applications of adhesive materials, which include surgical sealants, mucoadhesive drug delivery vehicles, and prevention of adhesion on medical devices. From Nature to Applications. Bioadhesion is often defined as the state in which two materials, at least one of which is biological in nature, are held together for extended periods of time by interfacial forces. This book highlights different aspects of this phenomenon. The first section of the book describes studies of natural adhesives. These include wet adhesives that are produced and secreted by sessile marine organisms such as mussels and algae and dry adhesives such as the one characterizing the gecko foot. The second section focuses on biomimetic adhesives. These man-made materials are fabricated on the basis of the lessons learned Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered significant scientific interest in the biomedical research community owing to the unique properties of fluorinated materials and the 19F nucleus. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body and thus there is no background signal. Fluorine-containing compounds are ideal tracer labels for a wide variety of MRI applications. Moreover, the chemical shift and nuclear relaxation rate can be made responsive to physiology via creative molecular design. This book is an interdisciplinary compendium that details cutting-edge science and medical research in the emerging field of 19F MRI. Edited by Ulrich Floegel and Eric Ahrens, two prominent MRI researchers, this book will appeal to investigators involved in MRI, biomedicine, immunology, pharmacology, probe chemistry, and imaging physics. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. In recent years, the understanding of the pathophysiological processes of atherosclerosis, a chronic inflammatory disease of the vessel wall being the leading cause for mortality in industrial countries, has tremendously increased. The feasibility of translating such knowledge to novel therapeutic approaches is currently being explored at various levels. This book highlights advances in atherosclerosis and links these to relevant therapeutic strategies. It compiles and details cutting-edge research in cardiovascular medicine from internationally renowned authors. In recent years, the understanding of the pathophysiological processes of atherosclerosis, a chronic inflammatory disease of the vessel wall being the leading cause for mortality in industrial countries, has tremendously increased. The feasibility of translating such knowledge to novel therapeutic approaches is currently being explored at various levels. This book highlights recent advances in atherosclerosis and to link these to relevant therapeutic strategies. It compiles and details cutting-edge research in cardiovascular medicine from internationally renowned authors. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. This book highlights state-of-the-art qubit implementations in semiconductors and provides an extensive overview of this newly emerging field. Semiconductor nanostructures have huge potential as future quantum information devices as they provide various ways of qubit implementation (electron spin, electronic excitation) as well as a way to transfer quantum information from stationary qubits to flying qubits (photons). Therefore, this book unites contributions from leading experts in the field, reporting cutting-edge results on spin qubit preparation, read-out and transfer. The latest theoretical as well as experimental studies of decoherence in these quantum information systems are also provided. Novel demonstrations of complex flying qubit states and first applications of semiconductor-based quantum information devices are given, too. Semiconductor nanostructures provide simultaneously various ways of qubit implementation as well as a way to transfer quantum information from these stationary qubits to flying qubits (photons). This book highlights the qubit implementations in semiconductors and provides an overview of this field. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. This book details cutting-edge research in bioceramics science based on an interdisciplinary approach that directly bridges orthopedic concepts to surface science, physical chemistry, biomedical optics and nanomechanics. Raman and cathodoluminescence spectroscopy are, among more conventional spectroscopic characterization techniques, cited in the book, used to their most advanced extents to unveil molecular scale phenomena of both chemical and mechanical origin occurring at the sliding surfaces of bioceramic joints. The concepts are relevant to the development of new biomaterials. This book details cutting-edge research in bioceramics science based on an interdisciplinary approach that directly bridges orthopedic concepts to surface science, physical chemistry, biomedical optics and nanomechanics. Raman and cathodoluminescence spectroscopy are, among more conventional spectroscopic characterization techniques, cited in the book, used to their most advanced extents to unveil molecular scale phenomena of both chemical and mechanical origin occurring at the sliding surfaces of bioceramic joints. The concepts are relevant to the development of new biomaterials. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated in a number of diseases. This raises the question of their direct role in pathogenesis as well as their possible use as biomarkers. This book stems from the first international meeting on "Microvesicles and Nanovesicles in Health and Disease" held at Magdalen College, Oxford, in 2010. The purpose of the meeting was to bring together, for the first time, a range of experts from around the world to discuss the latest advances in this field. Key to the study of these vesicles is the availability of methodologies for their measurement in biological fluids. A major section of the meeting focused on a range of exciting new technologies which have been developed for this purpose. The presentations at this meeting form the basis of this book, which will appeal to basic scientists, clinicians, and those developing technology for the measurement of extracellular vesicles. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Scaffolds for tissue engineering are devices that exploit specific and complex physical and biological functions, in vitro or in vivo, and communicate through biochemical and physical signals with cells and, when implanted, with the body environment. Scaffolds are produced mainly with synthetic materials, and their fabrication technologies are derived from already well-established industrial processes, with some new specific technologies having been developed in the last years to address required complexities.Often, a generalist approach is followed for the translation of materials and technologies designed for other applications, without considering the specific role of scaffolds from a physical and biological point of view. The book illustrates scaffold design principles, with particular relevance to the biological requirements needed to control and drive the biological cross talk, and reviews materials and fabrication and validation methods. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. This book covers biodevices, mainly implantable or quirurgical, for the diagnosis or treatment of different pathologies, which benefit from the use of active materials as sensors or actuators. Such active or "intelligent" materials are capable of responding in a controlled way to different external physical or chemical stimuli by changing some of their properties. These materials can be used to design and develop sensors, actuators, and multifunctional systems with a large number of applications for developing biodevices and medical appliances. Current work on these fields entails problems related to synthesis, characterization, modeling, simulation, processing, and prototyping technologies, as well as device testing and validation, all of which are treated in depth in this book, for the several types of active or intelligent materials covered. The research presented in this book helps further development of medical devices, based on the additional functionalities that the use of active or "intelligent" materials, both as sensors and actuators, supplies. The main results exposed may help with the industrial expansion of this kind of materials as part of more complex systems. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. Gynaecologic oncology is one of the most important subjects in gynaecology and a very challenging field. The management of patients with gynaecological cancers is complex, as the impact of the outcome of such cancers can be critical. This handbook covers the basics of carcinogenesis and the advances in the prevention and management of all gynaecologic cancers, including breast cancer. Gynaecologic oncology has always been perceived as the most difficult subject in obstetrics and gynaecology, but this handbook proves it otherwise. The text is presented in a systematic and easy-to-understand manner and is supplemented by plenty of images and illustrations and up-to-date references from established sources. The book also introduces readers to the new FIGO 2009 staging system and will be a very useful reference for researchers and clinicians. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. The worldwide impact of HIV/AIDS is well recognized. This book provides for the first time a thorough and critical overview of current aspects, recent developments, and trends in the formulation and drug delivery concerning anti-HIV microbicides by leading scientists in the field. Additionally, pertinent regulatory aspects and socioeconomical issues related to the subject are discussed. In the absence of a cure, prophylaxis represents a cornerstone in the battle against infection. One promising strategy comprises the use around the time of sexual intercourse of vaginal/rectal products containing antiviral compounds, termed microbicides. It is now recognized that specific development of drug dosage forms and/or drug delivery systems is an indispensable aspect for the success of microbicides. Different groups strived over the last decade to optimize the biophysical and technological performance of traditional dosage forms (gels, tablets, and suppositories) to fulfill the specificities of microbicides use, without neglecting users preferences and affordability issues. Moreover, new formulation approaches, such as vaginal rings and films, nanotechnology-based systems, stimuli-sensitive formulations, targeted drug delivery systems, among others have been proposed and are currently undergoing pre-clinical or even clinical testing. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. An optical cavity confines light within its structure and constitutes an integral part of a laser device. Unlike traditional gas lasers, semiconductor lasers are invariably much smaller in dimensions, making optical confinement more critical than ever. In this book, modern methods that control and manipulate light at the micrometer and nanometer scales by using a variety of cavity geometries and demonstrate optical resonance from ultra-violet (UV) to infra-red (IR) bands across multiple material platforms are explored.The book has a comprehensive collection of chapters that cover a wide range of topics pertaining to resonance in optical cavities and are contributed by leading researchers in the field. The topics include theory, design, simulation, fabrication, and characterization of micrometer- and nanometer-scale structures and devices that support cavity resonance via various mechanisms such as FabryPerot, whispering gallery, photonic bandgap, and plasmonic modes. The chapters discuss optical cavities that resonate from UV to IR wavelengths and are based on prominent III-V material systems, including Al, In, and Ga nitrides, ZnO, and GaAs. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Hardcover. Condition: new. Hardcover. The enormous advances in the immunologic aspects of biotherapeutics and nanomedicines in the past two decades has necessitated an authoritative and comprehensive reference source that can be relied upon by immunologists, biomedical researchers, clinicians, pharmaceutical companies, regulators, venture capitalists, and policy makers alike. This text provides a thorough understanding of immunology, therapeutic potential, clinical applications, adverse reactions, and approaches to overcoming immunotoxicity of biotherapeutics and nanomedicines. It also tackles critical, yet often overlooked topics such as immune aspects of nano-bio interactions, current FDA regulatory guidances, complement activation-related pseudoallergy (CARPA), advances in nanovaccines, and immunogenicity testing of protein therapeutics. This book focuses on the immune stimulatory and suppressive effects of antibodies, peptides and other biopharmaceuticals, drug carrier liposomes, micelles, polymers, polymeric vesicles, dendrimers, carbon nanotubes, and other nanomedicines. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.