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Published by Springer, 2012
ISBN 10: 9401056579ISBN 13: 9789401056571
Seller: booksXpress, Bayonne, NJ, U.S.A.
Book Print on Demand
Soft Cover. Condition: new. This item is printed on demand.
Published by Kluwer Academic Publishers, Dordrecht, 1990
Seller: The Book Gallery, Jerusalem, Israel
245x165mm. X+603 pages. Hardcover. Spine slightly curved. Else in good condition. PLEASE NOTE: This item is overweight. We may ask for extra shipping costs. The book is in : English.
Published by Springer, 2012
ISBN 10: 9401056579ISBN 13: 9789401056571
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
Book
Condition: New.
Published by Springer, 2012
ISBN 10: 9401056579ISBN 13: 9789401056571
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Book Print on Demand
Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Published by Springer Verlag, 2012
ISBN 10: 9401056579ISBN 13: 9789401056571
Seller: Revaluation Books, Exeter, United Kingdom
Book
Paperback. Condition: Brand New. 603 pages. 10.10x6.10x1.40 inches. In Stock.
Published by Springer, 2012
ISBN 10: 9401056579ISBN 13: 9789401056571
Seller: Kennys Bookshop and Art Galleries Ltd., Galway, GY, Ireland
Book
Condition: New. Proceedings of the Twenty-Third Jerusalem Symposium on Quantum Chemistry and Biochemistry, held in Jerusalem, Israel, May 14-17, 1990 Editor(s): Pullman, A.; Jortner, Joshua. Series: Jerusalem Symposia. Num Pages: 603 pages, biography. BIC Classification: PSB. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 30. Weight in Grams: 932. . 2012. 1990th Edition. paperback. . . . .
Published by Springer Netherlands, 2012
ISBN 10: 9401056579ISBN 13: 9789401056571
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - One of the central problems in the study of the mechanism of DNA-ligand interactions is the existence and nature of sequence specificity with respect to the base pairs of DNA. The presence of such a specificity could be of particular significance because it might possibly mean the involvement of specific genes in the effectiveness of the different drugs. The elucidation of the factors responsible for the specificity could then be important for the development of compounds susceptible to contribute to the control of gene expression and also to the development of rationally conceived, improved new generations of effective and specific chemotherapeutic agents. Important recent achievements, experimental and theoretical, in the analysis of such sequence specificities open prospects for possible rapid progress in this field. The 23rd Jerusalem symposium was devoted to the exploration of these recent achievements in relation to many types of ligand, with special emphasis on antitumor drugs. All major types of interaction, intercalation, groove binding, covalent linking, coordination, have been considered. So was also the effect of the interaction on the structure and properties of the nucleic acids and the relationship between the interaction and biological or pharmacological activities. We feel that this Volume presents a relatively complete up-to-date account of the state of the art in this important field of research.
Published by Springer Netherlands, 2012
ISBN 10: 9401056579ISBN 13: 9789401056571
Seller: moluna, Greven, Germany
Book Print on Demand
Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Proceedings of the Twenty-Third Jerusalem Symposium on Quantum Chemistry and Biochemistry, held in Jerusalem, Israel, May 14-17, 1990 One of the central problems in the study of the mechanism of DNA-ligand interactions is the existence and nature of s.
Published by Springer, 2012
ISBN 10: 9401056579ISBN 13: 9789401056571
Seller: Kennys Bookstore, Olney, MD, U.S.A.
Book
Condition: New. Proceedings of the Twenty-Third Jerusalem Symposium on Quantum Chemistry and Biochemistry, held in Jerusalem, Israel, May 14-17, 1990 Editor(s): Pullman, A.; Jortner, Joshua. Series: Jerusalem Symposia. Num Pages: 603 pages, biography. BIC Classification: PSB. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 30. Weight in Grams: 932. . 2012. 1990th Edition. paperback. . . . . Books ship from the US and Ireland.
Published by Springer, 1990
ISBN 10: 0792308972ISBN 13: 9780792308973
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Book Print on Demand
Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Published by Springer 2012-10, 2012
ISBN 10: 9401056579ISBN 13: 9789401056571
Seller: Chiron Media, Wallingford, United Kingdom
Book
PF. Condition: New.
Published by Kluwer Academic Publishers, Dordrecht, 1990
ISBN 10: 0792308972ISBN 13: 9780792308973
Seller: Cadeby Books, Grimsby, United Kingdom
Book First Edition
Laminated Board. Condition: Good. Dutch 1990 laminated hardcover edition in good condition. Ex-library book with usual markings. No inscriptions.
Published by Springer Netherlands Okt 2012, 2012
ISBN 10: 9401056579ISBN 13: 9789401056571
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Book Print on Demand
Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the central problems in the study of the mechanism of DNA-ligand interactions is the existence and nature of sequence specificity with respect to the base pairs of DNA. The presence of such a specificity could be of particular significance because it might possibly mean the involvement of specific genes in the effectiveness of the different drugs. The elucidation of the factors responsible for the specificity could then be important for the development of compounds susceptible to contribute to the control of gene expression and also to the development of rationally conceived, improved new generations of effective and specific chemotherapeutic agents. Important recent achievements, experimental and theoretical, in the analysis of such sequence specificities open prospects for possible rapid progress in this field. The 23rd Jerusalem symposium was devoted to the exploration of these recent achievements in relation to many types of ligand, with special emphasis on antitumor drugs. All major types of interaction, intercalation, groove binding, covalent linking, coordination, have been considered. So was also the effect of the interaction on the structure and properties of the nucleic acids and the relationship between the interaction and biological or pharmacological activities. We feel that this Volume presents a relatively complete up-to-date account of the state of the art in this important field of research. 616 pp. Englisch.
Published by Springer, 1990
ISBN 10: 0792308972ISBN 13: 9780792308973
Seller: booksXpress, Bayonne, NJ, U.S.A.
Book Print on Demand
Hardcover. Condition: new. This item is printed on demand.
Published by Kluwer Academic Publishers, 1990
ISBN 10: 0792308972ISBN 13: 9780792308973
Seller: THE SAINT BOOKSTORE, Southport, United Kingdom
Book Print on Demand
Hardback. Condition: New. This item is printed on demand. New copy - Usually dispatched within 5-9 working days.
Published by Kluwer Academic Pub, 1991
ISBN 10: 0792308972ISBN 13: 9780792308973
Seller: Revaluation Books, Exeter, United Kingdom
Book
Hardcover. Condition: Brand New. 603 pages. 9.21x6.14x1.31 inches. In Stock.
Published by Springer, 1991
ISBN 10: 0792308972ISBN 13: 9780792308973
Seller: Mispah books, Redhill, SURRE, United Kingdom
Book
Hardcover. Condition: Like New. Like New. book.
Published by Springer Netherlands, 1990
ISBN 10: 0792308972ISBN 13: 9780792308973
Seller: moluna, Greven, Germany
Book Print on Demand
Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt.
Published by SPRINGER NATURE Okt 1990, 1990
ISBN 10: 0792308972ISBN 13: 9780792308973
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Book Print on Demand
Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Mutual Conformational Adaptation of Both Ligand and Receptor in Antitumor Drug-DNA Complexes.- DNA Drug Interactions studied with Polarized Light Spectroscopy: the DAPI Case.- Drug-DNA Recognition: Sequence Specificity of the DNA Minor Groove Binder Berenil.- Binding of Minor Groove Ligands to Short DNA Segments: Berenil Complexed with d(GCAATTGC)2 and d(GCTTAAGC)2.- The Sequence Specificity of Damage Caused by [125I]-Labelled Hoechst 33258 and UV/IodoHoechst 33258 in Intact Cells and in Cloned Sequences of Purified DNA which differ by a Small Number of Base Substitutions.- Structure and Dynamics of a [1:1] Drug-DNA Complex: Analysis of 2D NMR Data Using Molecular Mechanics and Molecular Dynamics Calculations.- Determination of Distamycin-A Binding Modes by NMR.- Molecular Mechanisms of DNA Sequence Recognition by Groove Binding Ligands: Biochemical and Biological Consequences.- Daunomycin Binding to DNA: from the Macroscopic to the Microscopic.- In Vitro Transcription Analysis of the Sequence Specificity of Reversible and Irreversible Complexes of Adriamycin with DNA.- Quantitative Footprinting Analysis of the Actiomycin D-DNA Interaction.- Structural Requirements for DNA Topoisomerase II Inhibition by Anthracyclines.- Thermodynamic Studies of Amsacrine Antitumor Agents with Nucleic Acids.- Kinetic and Equilibrium Binding Studies of a Series of Intercalating Agents that Bind by Threading a Sidechain Through the DNA Helix.- Aminoacyl-Anthraquinones: DNA-Binding and Sequence Specificity.- The Molecular Basis of Specific Recognition Between Echinomycin and DNA.- Bis-Pyrrolecarboxamides Linked to Intercalating Chromophore Oxazolopyridocarbazole (OPC): Properties Related to the Selective Binding to DNA at Rich Sequences.- Parallel-Stranded Nucleic Acids and their Interaction with Intercalating and Groove Binding Drugs.- Design of Bifunctional Nucleic Acid Ligands.- Sequence-Specific Recognition and CLeavage of Duplex DNA by Derivatized Oligonucleotides.- Bis(Platinum) Complexes. Chemistry, Antitumor Activity and DNA-Binding.- Interaction of Calicheamicin with DNA.- The Effects of Ligand Structure on Binding Mode and Specificity in the Interaction of Unfused Aromatic Cations with DNA.- Modulation of Protein-DNA Interactions by Intercalating and Nonintercalating Agents.- Antitumor Antibiotics Endowed with DNA Sequence Specificity.- Cationic Porphyrin-DNA Complexes: Specificity of Binding Modes.- Complementary Studies on Sequence Specificity in DNA-Antitumor Drugs Interactions.- Uranyl Photofootpring. DNA Structural Changes upon Binding of Mithramycin.- Characteristics of Noncovalent and Covalent Interactions of (+) and (-) Anti-Benzo[a]pyrene Diol Epoxide Stereoisomers of Different Biological Activities with DNA.- Aflatoxin-DNA Binding and the Characterization of Aflatoxin B1-Oligodeoxynucleotide Adducts by 1H NMR Spectroscopy.- Sequence Specific Isotope Effects on the Cleavage of DNA by Radical-Generating Drugs.- Quinolone-DNA Interaction: How a Small Drug Molecule Acquires High DNA Binding Affinity and Specificity.- Mechanisms of DNA Sequence Selective Modifications by Alkylating Agents.- Contrasting Mechanisms for the Sequence Recognition of DNA by(+)- and (-)-CC-1065.- Course of Recognition and Covalent Reactions Between Mitomycin C and DNA: Sequence Selectivity of a Cross-Linking Drug.- Triplex Forming Oligonucleotide Reagents: Rationalization of DNA Site Selectivity and Application in a Pharmaceutical Context.- Experimental Proofs of a Drug's DNA Specificity. 616 pp. Englisch.
Published by Springer New York, 1990
ISBN 10: 0792308972ISBN 13: 9780792308973
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Mutual Conformational Adaptation of Both Ligand and Receptor in Antitumor Drug-DNA Complexes.- DNA Drug Interactions studied with Polarized Light Spectroscopy: the DAPI Case.- Drug-DNA Recognition: Sequence Specificity of the DNA Minor Groove Binder Berenil.- Binding of Minor Groove Ligands to Short DNA Segments: Berenil Complexed with d(GCAATTGC)2 and d(GCTTAAGC)2.- The Sequence Specificity of Damage Caused by [125I]-Labelled Hoechst 33258 and UV/IodoHoechst 33258 in Intact Cells and in Cloned Sequences of Purified DNA which differ by a Small Number of Base Substitutions.- Structure and Dynamics of a [1:1] Drug-DNA Complex: Analysis of 2D NMR Data Using Molecular Mechanics and Molecular Dynamics Calculations.- Determination of Distamycin-A Binding Modes by NMR.- Molecular Mechanisms of DNA Sequence Recognition by Groove Binding Ligands: Biochemical and Biological Consequences.- Daunomycin Binding to DNA: from the Macroscopic to the Microscopic.- In Vitro Transcription Analysis of the Sequence Specificity of Reversible and Irreversible Complexes of Adriamycin with DNA.- Quantitative Footprinting Analysis of the Actiomycin D-DNA Interaction.- Structural Requirements for DNA Topoisomerase II Inhibition by Anthracyclines.- Thermodynamic Studies of Amsacrine Antitumor Agents with Nucleic Acids.- Kinetic and Equilibrium Binding Studies of a Series of Intercalating Agents that Bind by Threading a Sidechain Through the DNA Helix.- Aminoacyl-Anthraquinones: DNA-Binding and Sequence Specificity.- The Molecular Basis of Specific Recognition Between Echinomycin and DNA.- Bis-Pyrrolecarboxamides Linked to Intercalating Chromophore Oxazolopyridocarbazole (OPC): Properties Related to the Selective Binding to DNA at Rich Sequences.- Parallel-Stranded Nucleic Acids and their Interaction with Intercalating and Groove Binding Drugs.- Design of Bifunctional Nucleic Acid Ligands.- Sequence-Specific Recognition and CLeavage of Duplex DNA by Derivatized Oligonucleotides.- Bis(Platinum) Complexes. Chemistry, Antitumor Activity and DNA-Binding.- Interaction of Calicheamicin with DNA.- The Effects of Ligand Structure on Binding Mode and Specificity in the Interaction of Unfused Aromatic Cations with DNA.- Modulation of Protein-DNA Interactions by Intercalating and Nonintercalating Agents.- Antitumor Antibiotics Endowed with DNA Sequence Specificity.- Cationic Porphyrin-DNA Complexes: Specificity of Binding Modes.- Complementary Studies on Sequence Specificity in DNA-Antitumor Drugs Interactions.- Uranyl Photofootpring. DNA Structural Changes upon Binding of Mithramycin.- Characteristics of Noncovalent and Covalent Interactions of (+) and (-) Anti-Benzo[a]pyrene Diol Epoxide Stereoisomers of Different Biological Activities with DNA.- Aflatoxin-DNA Binding and the Characterization of Aflatoxin B1-Oligodeoxynucleotide Adducts by 1H NMR Spectroscopy.- Sequence Specific Isotope Effects on the Cleavage of DNA by Radical-Generating Drugs.- Quinolone-DNA Interaction: How a Small Drug Molecule Acquires High DNA Binding Affinity and Specificity.- Mechanisms of DNA Sequence Selective Modifications by Alkylating Agents.- Contrasting Mechanisms for the Sequence Recognition of DNA by(+)- and (-)-CC-1065.- Course of Recognition and Covalent Reactions Between Mitomycin C and DNA: Sequence Selectivity of a Cross-Linking Drug.- Triplex Forming Oligonucleotide Reagents: Rationalization of DNA Site Selectivity and Application in a Pharmaceutical Context.- Experimental Proofs of a Drug's DNA Specificity.