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  • Victor Clarence Vaughan

    Published by Forgotten Books, 2018

    ISBN 10: 0260175889 ISBN 13: 9780260175885

    Seller: Forgotten Books, London, United Kingdom

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    Paperback. Condition: New. Print on Demand. This book explores the physiological chemistry of uric acid, particularly focusing on its formation and the influence of various factors on its production in the body. The author begins by acknowledging the groundbreaking discovery that uric acid originates from the breakdown of cell nuclei in the presence of oxidizing agents, setting forth the foundation for the investigation of uric acid metabolism. The book delves into the intricate relationship between uric acid and the disintegration of nucleated cells, highlighting the role of nuclein as the primary source of uric acid. The author discusses the significance of nuclein in the composition of cell nuclei, particularly in the lymphocytes of the thymus gland, and explores the chemical constituents of these nuclei, including nucleohiston, histon, and nucleinic acid. The book emphasizes the importance of nucleohiston in the process of coagulation and examines the impact of its components on blood clotting. Furthermore, the author investigates the role of protamins, basic proteids found in the spermatozoa of various animals, and their potential contribution to the formation of uric acid. The book delves into the phenomenon of chromatolysis, the dissolution and disintegration of nuclei, as a key process in the formation of alloxuric bodies, including uric acid. The author presents evidence suggesting that the disintegration of leukocytes is a constant source of uric acid, and explores the complex relationship between hyperleukocytosis and leukolysis in influencing uric acid production. The book also examines the impact of food, particularly the consumption of animal products, on uric acid formation, acknowledging the presence of nucleo-proteids and alloxuric bodies in meat and the stimulation of digestion-leukocytosis by animal-based diets. The author concludes by discussing the potential role of certain poisons and pathologic growths in altering cell proliferation and contributing to uric acid production. Overall, this book provides a comprehensive examination of the physiological chemistry of uric acid, offering valuable insights into its formation, sources, and the influence of various factors on its production in the body. Forgotten Books publishes hundreds of thousands of rare and classic books. This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works. The digital edition of all books may be viewed on our website before purchase. print-on-demand item.