2004 HC Protein Crystallography in Drug Discovery (Methods and Principles in Medicinal Chemistry)
Babine, Robert E. [Editor]; Abdel-Meguid, Sherin S. [Editor]; Mannhold, Raimund [Series Editor]; Kubinyi, Hugo [Series Editor]; Folkers, Gerd [Series Editor];
Language: English
Published by Vch Verlagsgesellschaft Mbh, 2004
- Hardcover
- Used
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- Title
- 2004 HC Protein Crystallography in Drug Discovery (Methods and Principles in Medicinal Chemistry)
- Author
- Babine, Robert E. [Editor]; Abdel-Meguid, Sherin S. [Editor]; Mannhold, Raimund [Series Editor]; Kubinyi, Hugo [Series Editor]; Folkers, Gerd [Series Editor];
- Publisher
- Vch Verlagsgesellschaft Mbh
- Publication year
- 2004
- Condition
- Good
- Binding
- hardcover
- Language
- English
- ISBN 10
- 3527306781
- ISBN 13
- 9783527306787
- Item weight
- 32 ounces
- Dimensions
- 7x1x9
Here, researchers from leading pharmaceutical companies present valuable first-hand information, much of it published for the first time. They discuss strategies to derive high-resolution structures for such important target protein classes as kinases or proteases, as well as selected examples of successful protein crystallographic studies. A special section on recent methodological developments, such as for high-throughput crystallography and microcrystallization, is also included.
A valuable companion for crystallographers involved in protein structure determination as well as drug developers pursuing the structure-based approach for use in their daily work.
"Synopsis" may belong to another edition of this title.
About the Author
******
Sherin S. Abdel-Meguid is Chief Scientific Officer and Founder of Suntory Pharmaceutical Research Laboratories (SPRL), a structure-based drug discovery company located in Cambridge, Massachusetts. He joined SPRL from SmithKline Beecham (SB) where he was Director of Macromolecular Sciences and Structural Biology, and director of the IL18, Herpes virus protease and CD28 programs. Prior to his work for SB, he was Head of Biophysical Sciences and Protein Engineering at Monsanto. At Monsanto, he built one of the first macromolecular crystallography groups in the pharmaceutical industry. He holds a Ph.D. in Physical Chemistry and M.S. and B.S. degrees in Biochemistry.
"About the title" may belong to another edition of this title.
Miki Store
San Jose, CA, U.S.A.
AbeBooks seller since December 14, 2023
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