3D Qsar in Drug Design : Recent Advances

Kubinyi, Hugo (EDT); Martin, Yvonne Connolly (EDT); Folkers, Gerd (EDT)

ISBN 10: 0792347919 / ISBN 13: 9780792347910

Published by Kluwer/ESCOM, 1998

Seller Inventory # 755775-n

Synopsis:

Significant progress has been made in the study of three-dimensional quantitative structure-activity relationships (3D QSAR) since the first publication by Richard Cramer in 1988 and the first volume in the series, 3D QSAR in Drug Design. Theory, Methods and Applications, published in 1993. The aim of that early book was to contribute to the understanding and the further application of CoMFA and related approaches and to facilitate the appropriate use of these methods. Since then, hundreds of papers have appeared using the quickly developing techniques of both 3D QSAR and computational sciences to study a broad variety of biological problems. Again the editor(s) felt that the time had come to solicit reviews on published and new viewpoints to document the state of the art of 3D QSAR in its broadest definition and to provide visions of where new techniques will emerge or new appli- tions may be found. The intention is not only to highlight new ideas but also to show the shortcomings, inaccuracies, and abuses of the methods. We hope this book will enable others to separate trivial from visionary approaches and me-too methodology from in- vative techniques. These concerns guided our choice of contributors. To our delight, our call for papers elicited a great many manuscripts.

Review: `... Volume 3 is a valuable resource text for scientists with a background or serious interest in 3D QSAR who are interested in CoMFA and related methodology. overall this 3 book series is a wonderful reference source for scientists interested 3D QSAR.'
SIM News, 49:4 (1999)

Bibliographic Details

Title: 3D Qsar in Drug Design : Recent Advances
Publisher: Kluwer/ESCOM
Publication Date: 1998
Binding: Hardcover
Condition: New
Edition: 2nd Edition