Designed for advanced courses, this text describes the uses of four spectroscopic UV, IR, NMR and mass spectra in organic chemistry. New material includes coverage of 2D NMR spectra and the introduction of the powerful techniques of TOCSY (Total Correlation Spectroscopy), ESI (Electrospray Ionization) and MALDI (Matrix-assisted Laser Desorption). This new edition also includes more worked examples and problems in the structure determination of small and large molecules.
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Dudley Williams was an undergraduate at the University of Leeds (1955-1958), and obtained his PhD (1958-1961) there under the supervision of Professor Basil Lythgoe. Following postdoctoral research at Stanford University (1961-1964) with Professor Carl Djerassi, he followed an academic career in Cambridge, as a Fellow of Churchill College, and in the Department of Chemistry. His research involved developments in proton nuclear magnetic resonance and mass spectrometry, and, most famously, he and his co-workers elucidated the structure and mode of action of the clinically important antibiotic vancomycin.
Ian Fleming studied at Pembroke College, Cambridge, obtaining his PhD in 1962 in the University Chemical Laboratory supervised by Dr John Harley-Mason. Except for a postdoctoral year at Harvard (1963-1964) with Professor R. B. Woodward, and sabbatical visits to McGill University in Montreal (1972 And 1978), the University of Wisconsin in Madison (1980), and Harvard University (1990), he has spent his entire academic career in Cambridge. In research, he is best known for his work on the application of organosilicon chemistry to solving problems of regiocontrol and stereocontrol in organic synthesis.
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