Tay-Sachs Disease (Volume 44) (Advances in Genetics, Volume 44) - Hardcover

Hardcover

ISBN 10: 0120176440 ISBN 13: 9780120176441

Publisher: Academic Press, 2001

Synopsis

Tay-Sachs disease is a rare hereditary disease caused by a genetic mutation that leaves the body unable to produce an enzyme necessary for fat metabolism in nerve cells, producing central nervous system degeneration. In infants, it is characterized by progressive mental deterioration, blindness, paralysis, epileptic seizures, and death by age four. Adult-onset Tay-Sachs occurs in persons who have a genetic mutation that is similar but allows some production of the missing enzyme. There is no treatment for Tay-Sachs.A test to determine whether an infant is carrying the Tay-Sachs disease was introduced in 1969. However, work continues to be done to help find a cure. Because there is no cure for this deadly disease, genetic research is essential. Advances in Genetics presents an eclectic mix of articles of use to all human and molecular geneticists. They are written and edited by recognized leaders in the field and make this an essential series of books for anyone in the genetics field.

About this title

About the Author

Robert J. Desnick, Mount Sinai School of Medicine, New York, New York, U.S.A.
Michael M. Kaback, University of California, San Diego, U.S.A.

Edition details

• Publisher: Academic Press
• Publication date: 2001
• Language: English
• ISBN 10: 0120176440
• ISBN 13: 9780120176441
• Binding: Hardcover
• Edition number: 1
• Number of pages: 363
• Editor: Desnick Robert J., Kaback Michael M.