With the explosion of combinatorial solid-phase methods, access to information has become one of the main barriers facing a synthetic chemist who is contemplating a combinatorial approach to a medicinal chemistry problem. The Combinatorial Index is an answer to that problem. This compendium of methods from the primary literature provides quick and convenient access to reliable synthetic transformations as well as information on linkers and analytical methods. Each synthetic procedure is preceded by a section entitled"Points of Interest,"which highlights the strengths and weaknesses of the various studies. The index also covers the use of solution-based synthesis for the generation of molecular diversity.
"synopsis" may belong to another edition of this title.
Combinatorial chemistry has become a major focus of research activity for pharmaceutical, agrochemical, and biotechnology companies. The explosion of combinatorial methods has created the need for a compendium of reliable synthetic transformations from the primary literature. The Combinatorial Index fills this need. Included are chapters on linkers, solid-phase synthetic methods, analytical techniques, and solution libraries. Procedures from the literature for constructing combinatorial libraries of small molecules comprise an indispensable laboratory reference for the synthetic chemist. Each procedure in the compilation is preceded by a section entitled "Points of Interest," which highlights the strengths and limitations of the various methods. A structural appendix covers both functional group transformations and heterocyclization reactions in solid-phase synthesis. This comprehensive but easy-to-access guide to the combinatorial chemistry literature will save time on tedious library searches, introduce a growing audience of chemists to this exciting field, and lower the barriers to attempting a new or related methodology.Review:
"The Combinatorial Index provides a comprehensive collection of experimental protocols that will be of considerable practical utility to researcher working in the field of combinatorial chemistry. The organization of The Combinatorial Index provides rapid and straightforward access to classes of chemical transformation, linkers, and compound structures." --Jonathan Ellman, University of California at Berkeley
"The Combinatorial Index is an indispensable reference for the solid-phase organic chemist. Both classic and modern techniques are presented in an easy-to-find format that is useful as a reference in the lab as well as a source of new ideas." --Ronald N. Zuckermann, Chiron Corporation
"About this title" may belong to another edition of this title.
Book Description Book Condition: Brand New. Brand New Original US Edition, Perfect Condition. Printed in English. Excellent Quality, Service and customer satisfaction guaranteed!. Bookseller Inventory # AIND-1258
Book Description Book Condition: New. New. US edition. Perfect condition. Customer satisfaction our priority. Bookseller Inventory # ABE-FEB-15585
Book Description Book Condition: Brand New. New. US edition. Customer Satisfaction guaranteed!!. Bookseller Inventory # SHUB15585
Book Description Academic Press, 1998. Hardcover. Book Condition: New. book. Bookseller Inventory # 0121413403
Book Description Book Condition: New. Brand New Original US Edition.We Ship to PO BOX Address also. EXPEDITED shipping option also available for faster delivery. Bookseller Inventory # AUSBNEW-1258
Book Description Book Condition: Brand New. New, US edition. Excellent Customer Service. Bookseller Inventory # ABEUSA-15585
Book Description Elsevier -, -. Book Condition: NEW. -- (illustrator). Original Books from across the World in Brand New Condition --------- It can be shipped from U.S, Canada, Germany & India/Overseas centre subject to availability.____9780121413408. book. Bookseller Inventory # RM-BS-680d
Book Description Book Condition: New. Dust Jacket Condition: New. Brand new, Perfect condition, Satisfaction Guaranteed, 24x7 Customer Service-0614914247. book. Bookseller Inventory # newabe-5361
Book Description Book Condition: Brand New. Book Condition New, U.S. EDITION. We Do not Ship APO FPO AND PO BOX. . Printing in English language.NO CD AND ACCESS CODE. Quick delivery by USPS/UPS/DHL/FEDEX/ARAMEX ,Customer satisfaction guaranteed. We may ship the books from Asian regions for inventory purpose. Bookseller Inventory # ABE ORG##CB100
Book Description Academic Press, 2017. Hardcover. Book Condition: New. This item is printed on demand. Bookseller Inventory # P110121413403