Neurotoxicology: Approaches and Methods - Hardcover

Hardcover

ISBN 10: 012168055X ISBN 13: 9780121680558

Publisher: Academic Press, 1995

Synopsis

Neurotoxicology: Approaches and Methods provides a unique and comprehensive presentation of the current concepts and state-of-the-art methods for the assessment of neurotoxicity. The book analyzes various techniques available and discusses their strengths and weaknesses. This volume will serve as an excellent desk companion and laboratory guide for all investigators, researchers, clinicians, and students interested in neurotoxicology. The internationally knowngroup of editors divide the book into seven sections: Neuromorphological and Neuropathological Approaches; Neurophysiological Approaches; Neurobehavioral Toxicology; Neurochemical and Biomolecular Approaches; In-Vitro Models; Clinical Neurotoxicology; and Risk Assessment of Neurotoxicity. Each section yields the most up-to-date information by experts in their fields. Meticulously organized and edited, Neurotoxicology: Approaches and Methods is the most authoritative and well-planned neurotoxicology book on the market.

• Discusses neurobehavioral testing methods for assessment of neural dysfunctions
• Explains state-of-the-art diagnostic methods, such as clinico-neuropsychological and neurophysiological methods, for patients confronted by neurotoxic problems
• Discusses In Vitro methods, including aggregating brain cell methods, organotypic cultures, and the use of human neuronal cell lines for the assessment of neurotoxicity
• Presents step-by-step procedures for many methods
• Provides state-of-the-art neuromorphological and biomolecular methods and approaches for neurotoxicity investigation

About this title

From the Back Cover

Neurotoxicology: Approaches and Methods is a unique and comprehensive presentation of the current concepts and state-of-the-art methods for the assessment of neurotoxicity and for the understanding of the toxic mechanisms of many neurotoxicants. The book analyzes various techniques available and discusses their strengths and weaknesses. This volume will serve as an excellent desk companion and laboratory guide fore all investigators, researchers, clinicians, and students interested in neurotoxicology.

The internationally known group of editors divide the book into the following sections: Neuromorphological and Neuropathological Approaches, Neurophysiological Approaches and Methods, Neurobehavioral Toxicology, Neurochemical and Biomolecular Approaches, In Vitro Models, Clinical Neurotoxicology, and Risk Assessment for Neurotoxicity. Each section yields the most up-do-date information by experts in their fields.

Meticulously organized and edited, Neurotoxicology is the most authoritative and well-planned neurotoxicology book on the market.

:Key Features

• Discusses neurobehavioral testing methods for assessment of neural dysfunctions
• Explains state-of-the-art diagnostic methods, such as clinico-neuropsychological and neurophysiological methods, for patients confronted by neurotoxic problems
• Discusses in vitro methods, including aggregating brain cell methods, organotypic cultures, and the use of human neuronal cell lines for the assessment of neurotoxicity
• Presents step-by-step procedures for many methods
• Provides state-of-the-art neuromorphological and biomolecular methods and approaches for neurotoxicity investigation

About the Author

Louis W. Chang is a Professor in the Departments of Pathology, Pharmacology, and Toxicology at the University of Arkansas for Medical Sciences. He also served as the Director of the Toxicology Program and is the current Graduate Director of the Pathology Program in Arkansas. Aside from being the author of over 200 scientific articles, Dr. Chang also served on the editorial boards for a number of publications and scientific journals in his field. He is a well recognized scientist internationally. Dr. Chang has been recently elected as a Fellow of the Academy of Toxicological Sciences and has become a board certified Diplomate of the American Board of Forensic Examiners and a Diplomate of the American Board of Forensic Medicine. He received his B.A. from the University of Massachusetts, Amherst, his M.S. in Anatomy and Histochemistry from the Tufts University School of Medicine, and his Ph.D. in Pathology from the University of Wisconsin, Madison Medical School. Dr. Chang also received education and training from Harvard Medical School and the University of California, Los Angeles School of Medicine.

Dr. Slikker is the Director of FDA’s National Center for Toxicological Research (NCTR). He received his Ph.D. in Pharmacology and Toxicology from the University of California at Davis. Dr. Slikker holds Adjunct Professorships in the Departments of Pediatrics, and Pharmacology and Toxicology at the University of Arkansas for Medical Sciences. He has held committee chairmanships or elected offices in several scientific societies, including the Teratology Society (serving as President) and the American Society for Pharmacology and Experimental Therapeutics (Chair, Developmental Pharmacology Section and member of the Program Committee) and co-founder and past President of the MidSouth Computational Biology and Bioinformatics Society. He is currently Associate Editor for NeuroToxicology and Toxicological Sciences and is the past President of The Academy of Toxicological Sciences, the Society of Toxicology (Presidential term ended 2013), recipient of the 2014 George H. Scott Memorial Award from The Toxicology Forum and invited to present the Warkany Lecture at the 2015 annual meeting of the Teratology Society. Dr. Slikker has authored or co-authored over 300 publications in the areas of transplancental pharmacokinetics, developmental neurotoxicology, neuroprotection, systems biology, and risk assessment. He has also served on several national/international advisory panels for the International Life Sciences Institute (ILSI)/Health and Environmental Sciences Institute (HESI), Chemical Industry Institute of Toxicology (CIIT) Centers for Health Research, Environmental Protection Agency (EPA), National Institute of Environmental Health Sciences (NIEHS), National Academy of Sciences (NAS), National Institutes of Health (NIH) and World Health Organization (WHO).

Edition details

• Publisher: Academic Press
• Publication date: 1995
• ISBN 10: 012168055X
• ISBN 13: 9780121680558
• Binding: Hardcover
• Language: English
• Edition number: 1
• Number of pages: 851
• Editor: Chang Louis W., Slikker Jr. William