The Drosophila larval neuromuscular junction (NMJ) has become one of the most powerful model systems to ask key neurobiological questions. This synapse is unparalleled by its accessibility, its simplicity, and the ability to manipulate genes important for synapse development and function. Its synapses have properties shared by many organisms including humans. The vast majority of genes that when mutated cause congenital disorders of the nervous system in humans, are present in the fruit fly genome, and fly models of human disorders are available. Thus, this preparation is a powerful tool to understand the normal function of these genes.
This book reviews outstanding work by recognized leaders in the fields of Drosophila cellular neurogenetics including developmental neurobiology, mechanisms of synaptic function, and experience dependent changes at synapses. The book also includes step-by-step protocols to study the cellular biology of the NMJ, making it a vital resource for researchers beginning their investigations with this system, for those who are training students and postdoctoral fellows in this area, or simply as a general reference material for neuroscientists and neuroscience professors in general.
* Provides a synthesis of the main topics in modern neurogenetics
* Includes step-by-step protocols for the use of the Drosophila NMJ system in neurobiology lab research
* Offers genetic approaches to study synapse development and function
"synopsis" may belong to another edition of this title.
Reference for studying the Drosophila as a model system for neuroscience research.
"About this title" may belong to another edition of this title.
Book Description Academic Press, 2006. Book Condition: Very Good. 1st Edition. N/A. Former Library book. Great condition for a used book! Minimal wear. Bookseller Inventory # GRP12741173
Book Description Academic Press. Hardcover. Book Condition: Good. 0123736137 Good; Hardcover; Withdrawn library copy with standard library markings; Light-to-moderate shelfwear to covers with scuffing to top left corner back cover; Library stamps to endpapers; Text pages clean & unmarked; Good binding with straight spine; Blue covers with title in white lettering; 2006, Academic Press; 424 pages; "The Fly Neuromuscular Junction: Structure and Function, Volume 75: Second Edition (International Review of Neurobiology.)," by Vivian Budnik & Catalina Ruiz-Canada. Bookseller Inventory # SKU-Q5309012084