The Immunoglobulins: Structure and Function - Softcover

Nezlin, Roald

Softcover

ISBN 10: 0123887089 ISBN 13: 9780123887085

Publisher: Academic Press, 2012

Synopsis

This book provides comprehensive up-to-date information on the structure and function of immunoglobulins. It describes the basic features of these molecules, which assists the reader in understanding how they function as an integral part of the immune system. The Immunoglobulins describes the localization and structure of different binding sites of immunoglobulin molecules, including the antigen-binding site, on the basis of latest x-ray crystallography studies. It discusses recently developed biotechnological methods that allow scientists to obtain fully active antibody molecules in vitro even without immunization and to construct new variants of immunoglobulins and their fragments by fusing with various other active molecules. A survey of recent knowledge on immunoglobulin-binding molecules other than antigens and on flexibility of immunoglobulin molecules concludes the discussion of functional aspects of the problem.

About this title

About the Author

By Roald Nezlin

Review

"This is a fairly concise, but remarkably complete and up-to-date treatise on the immunoglobulins... excellent and thorough monograph on the immunoglobulins and a number of other specific receptor and ligand systems. The work is highly recommended to immunologists and molecular biologists."
--IMMUNOLOGICAL INVESTIGATIONS
"It is highly recommended to all immunologists. The book has rather extraordinary figures, including a section of color plates of computer generated immunoglobulin, antigen binding images, and x-ray structural analysis... This is a very timely monograph that has everything the non-Ig immunologist needs to know, and much more."
--DOODY'S PUBLISHING REVIEWS
"...provides good and informative reviews of many aspects of antibody research...the book provides many very good discussions, and provides just the right amount of detail about, for example, antibody-related molecules (e.g. T-cell receptors, MHC molecules and Fc receptors)and molecules that interact with antibodies...useful starting point for those wishing to make themselves familiar with the different aspects of antibody research...it is certainly recommendable."
@souce—Lutz Riechmann, MRC Laboratory of Molecular Biology, in TIBS (1999)

Edition details

• Publisher: Academic Press
• Publication date: 2012
• Language: English
• ISBN 10: 0123887089
• ISBN 13: 9780123887085
• Binding: Paperback
• Number of pages: 300