Synopsis
The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases.
- Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses.
- Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines...
About the Authors
Virginia M. Pickel, Ph.D., Department of Neurology and Neuroscience, Division of Neurobiology, Weill Cornell Medical College. Dr. Pickel received her M.S. from the University of Tennessee in Knoxville, and her Ph.Do from Vanderbilt University School of Medicine in Nashville. Her past appointment include NIH Postdoctoral and Staff Fellow, Laboratory of Neuropharmacology, St. Elizabeth's Hospital, NIMH, Washington, DC; and Professor of Neurobiology in Neurology and Neuroscience, Weill Cornell Medical...
From the Back Cover
The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. Part 1 provides an in depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse....
"About this title" may belong to another edition of this title.
- PublisherAcademic Press
- Publication date2013
- ISBN 10 0124186750
- ISBN 13 9780124186750
- BindingHardcover
- LanguageEnglish
- Edition number1
- Number of pages512
- EditorPickel PhD Virginia M., Segal PhD Menahem
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The Synapse: Structure and Function
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings. 512 pp. Englisch. Seller Inventory # 9780124186750
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The Synapse
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Buch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings. Seller Inventory # 9780124186750
Quantity: 2 available