Gene Therapy of Cancer: Translational Approaches From Preclinical Studies to Clinical Implementation (1st Edition)

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9780124371903: Gene Therapy of Cancer: Translational Approaches From Preclinical Studies to Clinical Implementation (1st Edition)

This book presents cancer gene therapy and its proposed use in the search for the prevention of cancer. Contributions from leaders in the field present laboratory research, various types of vector genes and gene therapy strategies, as well as clinical trials currently under way. The volume covers gene therapy as it evolves from laboratory technology and is parlayed into clinical investigations. Gene Therapy of Cancer describes the strategies for intervention and provides data demonstrating efficacy in in vitro as well as in vivo preclinical and clinical studies which lead to specific strategies for gene therapy. This volume is a comprehensive look into the subject of genetic approaches to cancer and is an important reference for scientists, students, and a general clinical audience.

Key Features
* Provides a comprehensive review of gene therapy targets in cancer
* Discusses specific strategies for gene therapy intervention and current gene therapy vehicles
* Provides data demonstrating clinical studies
* Explains the requirements of bringing new technologies to clinical use

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About the Author:

Edmund C. Lattime is currently with Department of Surgery, UMDNJ-Robert Wood Johnson Medical School, The Cancer Institute of New Jersey. He received his Ph.D. at Rutgers University and has a Postdoctoral Fellow (Cellular Immunology) from Sloan-Kettering Institute for Cancer. Dr. Lattime has been given a Young Investigator Award from the National Cancer Institute and a Scholar Award from the Leukemia Society of America. He is a member of several editorial boards and review committees, and is currently an academic advisor to the University of Michigan's "Genetic Approaches for Cancer Immunotherapy" Committee. He has been a corporate advisor to Schering-Plough's Bladder Cancer Advisory Board, and has written or contributed to many papers, articles and book chapters. Lattime is also a sought-after lecturer, having been invited to speak at many universities and conferences.

Stanton L. Gerson received his M.D. at Harvard Medical School. He was a Resident in Medicine at the Hospital of the University of Pennsylvania, where he became a Fellow in Hematology-Oncology in 1980. He is an Edward Mallinckrodt Jr. Foundation Scholar, and is currently Chief, Division of Hematology/Oncology at Case Western Reserve Univeristy, where he has served since 1983. Dr. Gerson is a member of several major professional and scientific societies and is a principal investigator of funded grants for several philanthropic organizations. He is author or a contributor to over 200 research papers, abstracts, theses and book chapters. Since 1987, Dr. Gerson has been invited to be a guest lecturer at over 40 national and international conferences.

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Edmund C. Lattime (Editor), Stanton L. Gerson (Editor)
Published by Academic Press (1999)
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