Since the First Edition of The Autoimmune Diseases was published in 1985, interest as well as knowledge about autoimmune diseases has greatly increased. This edition incorporates new material and combines the basic aspects of autoimmunity with discussion of specific autoimmune diseases in humans. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels. In addition to a comprehensive discussion of various autoimmune diseases and organ systems, the editors also cover the role of autoimmunity in cancer, AIDS, and aging.
Key Features
* Provides comprehensive discussions of all autoimmune diseases and organ systems
* Offers "bench to bedside" coverage of autoimmunity for both clinicians and research scientists
* Discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels
* Examines the environmental determinants of autoimmune disease
* Examines the association between autoimmunity and aging, cancer, and AIDS
"synopsis" may belong to another edition of this title.
The Autoimmune Diseases comprehensively describes the clinical expressions of all known autoimmune diseases, as well as the experimental bases of autoimmunity and failure of tolerance. The scientific chapters include mechanisms of natural tolerance, the genetic basis of autoimmunity, the significance of apoptosis, the influence of cytokines, environmental influences, and experimental models. The clinical chapters cover autoimmune endocrine deficiencies, insulin-dependent diabetes, rheumatic disorders, neurological diseases, and diseases of the blood, skin, eye, kidney, and liver.
Key Features:
* Provides comprehensive discussions of all autoimmune diseases and organ systems
* Offers "bench to bedside" coverage of autoimmunity for both clinicians and research scientists
* Discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels
* Examines the environmental determinants of autoimmune disease
* Examines the association between autoimmunity and aging, cancer, and AIDS
Awarded the highest rating by DOODY'S PUBLISHING REVIEWS -- Five Stars!
Selected as one of the 250 Best Books of 1998 by DOODY'S JOURNAL!
"About this title" may belong to another edition of this title.
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Hardcover. Condition: Fine. 3rd ed. Large quarto in green glossy paper-backed boards; vii, 895 pages: illustrations; 29 cm. Contents: Prelude / Noel R. Rose and Ian R. Mackay -- 1. Four Decades of Self and Non-Self: Reflections on Autoimmunity and Tolerance / Gustav J. V. Nossal -- 2. Basis and Mechanisms of Self-Tolerance / A. Basten -- 3. Transgenic Models of Peripheral T-Cell Self-Tolerance and Autoimmunity / J. F. A. P. Miller -- 4. Antigenic Determinants Involved in Induction and Propagation of Autoimmunity / Kamal D. Moudgil and Eli E. Sercarz -- 5. Costimulation and the Regulation of Autoimmunity / Kevin J. Lafferty and Lawrence S. Gazda -- 6. Genetic Influences: Major Histocompatibility Complex / William W. Kwok and Gerald T. Nepom -- 7. Non-MHC Genetic Contributions to Autoimmune Disease / Timothy J. Vyse, John A. Todd and Brian L. Kotzin -- 8. Environmental Determinants of Autoimmune Disease / Antony Rosen and Livia Casciola-Rosen -- 9. Infection and Autoimmune Disease / Leonard C. Harrison and Geoffrey J. McColl -- 10. Molecular Mimicry / Robert S. Fujinami -- 11. Antigen Receptors / Ellen Heber-Katz -- 12. T-Cell Subsets (Th1, Th2) and Cytokines in Autoimmunity / Sergio Romagnani -- 13. Apoptosis, Autoantigens, and Autoimmunity / Carlos A. Casiano and Eng M. Tan -- 14. Animal Models of Autoimmunity: Spontaneous and Induced / Pierluigi E. Bigazzi -- 15. Blood Cells: Autoimmune Hemolytic Anemia / Bruce C. Gilliland -- 16. Blood Cells: Autoimmune Thrombocytopenia Purpura / Bruce C. Gilliland -- 17. Systemic Lupus Erythematosus / Morris Reichlin -- 18. Antiphospholipid/Cofactor Syndromes / Donato Alarcon-Segovia and Antonio R. Cabral -- 19. Systemic Sclerosis (Scleroderma) / Claudio Galperin and M. Eric Gershwin -- 20. Rheumatoid Arthritis / John S. Sundy and Barton F. Haynes -- 21. Sjogren's Syndrome / M. N. Manoussakis, N. Talal and H. M. Moutsopoulos -- 22. Autoimmune Thyroid Disease / Anthony P. Weetman -- 23. Diabetes / Sabine Bieg and Ake Lernmark -- 24. Autoimmune Gastritis and Pernicious Anemia / Ban-Hock Toh, Paul A. Gleeson and Senga Whittingham -- 25. Inflammatory Bowel and Celiac Disease / David E. Elliott, Joseph A. Murray and Joel V. Weinstock -- 26. Autoimmune Diseases: The Liver / Michael P. Manns, Birgit Luttig and Petra Obermayer-Straub -- 27. Cutaneous Autoimmune Diseases / Mong-Shang Lin, Zhi Liu and Beth A. Drolet -- 28. Autoimmune Diseases of the Central and Peripheral Nervous Systems / Barry G. W. Arnason -- 29. Autoimmune Disease in the Kidney / Lorraine C. Racusen -- 30. Immune-Mediated Cardiovascular Disease / Noel R. Rose and Kenneth L. Baughman -- 31. Myasthenia Gravis / Daniel B. Drachman -- 32. Autoimmune Diseases of Muscle / Peter N. Hollingsworth, Michael J. Garlepp and Roger L. Dawkins -- 33. Autoimmune Disease of the Testis and the Ovary / Kenneth S. K. Tung -- 34. Vasculitis / J. Charles Jennette and Ronald J. Falk -- 35. Adrenal Autoimmunity and the Autoimmune Polyglandular Syndromes Types I-III: Addison's Disease, Hypoparathyroidism, and Hypophysitis / Yao-Hua Song, Yangxin Li and Noel K. MacLaren -- 36. Autoimmune Diseases of the Eye / Mitchell H. Friedlaender and Hiroshi Fujishima -- 37. Autoimmune Diseases: Cameos, Curiosities, and Shadowlands / Ian R. Mackay -- 38. Aging and Autoimmunity / John S. Manavalan, Irena Kirman and Kesheng Zhao -- 39. Paraneoplastic Autoimmune Syndromes / Grant J. Anhalt and Hossein C. Nousari -- 40. Autoimmune Derangements in the Acquired Immunodeficiency Syndrome / Franco Silvestris, Franco Dammacco and Ralph C. Williams, Jr. -- 41. Diagnosis of Autoimmune Disease / R. L. Dawkins, O. P. Martinez and E. M. Freitas -- 42. Novel Therapeutic Approaches to Autoimmunity / Reinhard Hohlfeld and Hartmut Wekerle -- 43. Autoimmunity Yesterday, Today, and Tomorrow / Ian R. MacKay and Noel R. Rose. ** Weighs 5.3 lbs before packaging.Extra shipping costs may apply.**. Fine copy with very faint external wear. Binding tight; pages clean but for a small "83" in pen to fron free end paper upper outer c. Seller Inventory # 87330
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