Biosensors are becoming increasingly important bioanalytical tools in the pharmaceutical, biotechnology, food, and other consumer oriented industries. The technology, though well developed in Europe, is slowly developing and has begun to generate interest in the United States only over the past couple of years. Research is now being directed toward the development of biosensors that are versatile, economical, and simple to use.Engineering Biosensors is a comprehensive introduction to biosensors that includes numerous illustrations to further explain the main concepts and practical examples from existing literature. It describes what biosensors are, where they are used, and how their performance is affected by existing surface characteristics.A better understanding of biosensors, as provided by this book, will greatly assist in the design of new as well as the improvement of existing biosensors. Readers are also provided with invaluable and hard-to-find data on the economics of the biosensor market to assist them in better understanding the market and where it is heading.
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Dr. Ajit Sadana has recently retired from the University of Mississippi after 34 years. His expertise is in the area of kinetics of binding and dissociation of analytes on biosensor surfaces.
Analysis of the binding between an analyte and a receptor is a key step in the design of immunodiagnostic assays and biosensors. This book describes and makes more quantitative the binding kinetics between an analyte and a receptor using a technique based on fractals. Actual examples from the existing literature are provided to illustrate the simplicity and the wide applicability of the technique. A better understanding of the binding interactions on the biosensor surface will greatly assist in the design as well as in the improvement of existing biosensors. In addition, the book deals with the economics of the biosensor market, and its past, present, and future trends.KEY FEATURES:· Describes a simple, rapid, and robust technique for evaluating binding kinetics in biosensors · Includes a large number of examples illustrating the mathematical techniques· Contains difficult to find data on existing biosensor industry economics· Provides comprehensive introduction to biosensors, including illustrations to better explain the main concepts· Includes recommendations to help design and improve existing biosensors· Supplies useful information for biologists, chemists, and mathematicians· Draws a distinction between classical modeling techniques and fractal models The techniques described will provide chemists, biologists, and mathematicians with an alternative technique for better modeling and describing complex analyte-receptor binding kinetics. This book should help those in the biosensor industry to better understand the existing market and to predict where the market is heading.
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