Metabolic Engineering: Principles and Methodologies

4.04 avg rating
( 26 ratings by GoodReads )
 
9780126662603: Metabolic Engineering: Principles and Methodologies

Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes.
Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems.


Key Features
* Demonstrates metabolic engineering in action with numerous examples of pathway modification
* Includes methods for identifying key enzymes in metabolic networks
* Contains a comprehensive review of metabolic biochemistry
* Discusses metabolic regulation at the gene, enzyme, operon, and cell levels
* Explains concepts of stoichiometry, kinetics, and thermodynamics of metabolic pathways
* Minimizes mathematical complexity
* Links to a Web page to communicate updates of the software code and homework problems

"synopsis" may belong to another edition of this title.

From the Back Cover:

Metabolic engineering is an emerging, interdisciplinary field with applications to the production of chemicals, fuels, materials, and pharmaceuticals. The field's novelty lies in the integration of the techniques of molecular biology with the tools of mathematical analysis, to help elucidate metabolic flux control and rational selection of targets for genetic modification. By providing a rigorous description of cell physiology, metabolic engineering also facilitates functional genomics. Its primary objective is to identify specific genetic and environmental manipulations that lead to enhancement of yield and productivity of biotechnological processes, or the overall improvement of cellular properties.
Key elements of the book include pathway integration and consideration of metabolic flux as a fundamental determinant of cell physiology. Metabolic Engineering keeps mathematical complexity to a minimum ,and provides sidebars as additional background on various mathematical operations. Computational tools for pathway analysis are described, and a glossary of biological terms facilitates use of the book by a broad audience of biochemists, molecular biologists, microbiologists, and biochemical/biomedical engineers.

About the Author:

Gregory Stephanopoulos is a Professor of Chemical Engineering at MIT. He received his B.S. from the National Technical University of Athens, his M.S. from the University of Florida and his Ph.D. from the University of Minnesota, all in Chemical Engineering. Upon graduation, he joined the Chemical Engineering Faculty of the California Institute of Technology, where he served as Assistant and Associate Professor until 1985. In 1985 he was appointed Professor of Chemical Engineering at MIT where he has been ever since.Stephanopoulos' work has appeared in more than 150 publications and 7 patents. He has been recognized with the Dreyfus Foundation Teacher Scholar Award (1982), Excellence in Teaching Award (1984), and Technical Achievement Award of the AIChE (1984). He has been a Presidential Young Investigator and the Chairman of the Food Pharmaceutical & Bioengineering Division of the American Institute of Chemical Engineers (1992). In 1992 he was a Visiting Professor at the International Research Center for Biotechnology at Osaka University and was elected a Founding Fellow of the American Institute for Medical and Biological Engineering. In 1996 he chaired the first Conference on Metabolic Engineering and gave the inaugural Bayer Lecture on Biochemical Engineering at the University of California at Berkeley. He was honored with the FPBE Division Award at AIChE in 1997.

"About this title" may belong to another edition of this title.

Top Search Results from the AbeBooks Marketplace

International Edition
International Edition

1.

Gregory N. Stephanopoulos, Aristos A. Aristidou & Jens Nielsen
ISBN 10: 0126662606 ISBN 13: 9780126662603
New Softcover First Edition Quantity Available: > 20
International Edition
Seller
GREAT BOOKS DEAL
(TALLAHASSEE, FL, U.S.A.)
Rating
[?]

Book Description Softcover. Book Condition: New. 1st edition. Brand New; Paperback; Black & White or Color International Edition. ISBN and Cover page may differ but similar contents as US edition. GET IT FAST in 3-5 business days by DHL/FEDEX with tracking number. Books printed in English. No shipping to PO Box/APO/FPO address. In some instances, the international textbooks may have different end chapter case studies and exercises. International Edition Textbooks may bear a label "Not for sale in the U.S. or Canada" and "Content may different from U.S. Edition" - printed only to discourage U.S. students from obtaining an affordable copy. The U.S. Supreme Court has asserted your right to purchase international editions, and ruled on this issue. Access code or CD is not provided with these editions, unless specified. We may ship the books from multiple warehouses across the globe, including India depending upon the availability of inventory storage. Customer satisfaction guaranteed. Bookseller Inventory # INAB1486981

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 16.90
Convert Currency

Add to Basket

Shipping: US$ 3.95
Within U.S.A.
Destination, Rates & Speeds
International Edition
International Edition

2.

Stephanopoulos, Gregory N.; Aristidou, Aristos A.; Nielsen, Jens
Published by Academic Press
ISBN 10: 0126662606 ISBN 13: 9780126662603
New Softcover Quantity Available: > 20
International Edition
Seller
Sunshine Book Store
(Wilmington, DE, U.S.A.)
Rating
[?]

Book Description Academic Press. Book Condition: New. 0126662606 This is an International Edition. Brand New, Paperback, Delivery within 6-14 business days, Similar Contents as U.S Edition, ISBN and Cover design may differ, printed in Black & White. Choose Expedited shipping for delivery within 3-8 business days. We do not ship to PO Box, APO , FPO Address. In some instances, subjects such as Management, Accounting, Finance may have different end chapter case studies and exercises. International Edition Textbooks may bear a label "Not for sale in the U.S. or Canada" and "Content may different from U.S. Edition" - printed only to discourage U.S. students from obtaining an affordable copy. The U.S. Supreme Court has asserted your right to purchase international editions, and ruled on this issue. Access code/CD is not provided with these editions , unless specified. We may ship the books from multiple warehouses across the globe, including India depending upon the availability of inventory storage. Customer satisfaction guaranteed. Bookseller Inventory # SU9780126662603

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 21.20
Convert Currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, Rates & Speeds
International Edition
International Edition

3.

Stephanopoulos
ISBN 10: 0126662606 ISBN 13: 9780126662603
New Softcover Quantity Available: 10
International Edition
Seller
bookscollection
(Delhi, DELHI, India)
Rating
[?]

Book Description Book Condition: Brand New. PAPERBACK,Book Condition New, Brand New, Softcover, International Edition. We Do not Ship APO FPO AND PO BOX. Cover Image & ISBN may be different from US edition but contents as US Edition. Printing in English language. Quick delivery by USPS/UPS/DHL/FEDEX/ARAMEX ,Customer satisfaction guaranteed. We may ship the books from Asian regions for inventory purpose. Bookseller Inventory # ABESTTND1353

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 17.52
Convert Currency

Add to Basket

Shipping: US$ 3.93
From India to U.S.A.
Destination, Rates & Speeds
International Edition
International Edition

4.

Stephanopoulos
ISBN 10: 0126662606 ISBN 13: 9780126662603
New Soft cover First Edition Quantity Available: > 20
International Edition
Seller
LOW COST_FAST SHIP
(Scottsdale, AZ, U.S.A.)
Rating
[?]

Book Description Soft cover. Book Condition: New. Opt EXPEDITED shipping for 2 to 4 day delivery - Brand NEW - International Edition - 1ed - SAME Contents as in US edition - SHRINKwrapped BOXpacked - There is no CD or Access Code, unless specified above - Ships from various locations. Bookseller Inventory # C34

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 18.68
Convert Currency

Add to Basket

Shipping: US$ 5.99
Within U.S.A.
Destination, Rates & Speeds
International Edition
International Edition

5.

Stephanapoulus
ISBN 10: 0126662606 ISBN 13: 9780126662603
New Quantity Available: 5
International Edition
Seller
firstbookstore
(New Delhi, India)
Rating
[?]

Book Description Book Condition: Brand New. Brand New Paperback International Edition, Perfect Condition. Printed in English. Excellent Quality, Service and customer satisfaction guaranteed!. Bookseller Inventory # AIND-6646

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 25.54
Convert Currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, Rates & Speeds
International Edition
International Edition

6.

STEPHANOPOULOS ET.AL
ISBN 10: 0126662606 ISBN 13: 9780126662603
New Quantity Available: 5
International Edition
Seller
EBOOKSTORE2010
(New Delhi, ND, India)
Rating
[?]

Book Description Book Condition: Brand New. New. SoftCover International edition. Different ISBN and Cover image but contents are same as US edition. Customer Satisfaction guaranteed!!. Bookseller Inventory # SHUB92853

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 25.79
Convert Currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, Rates & Speeds
International Edition
International Edition

7.

STEPHANOPOULOS ET.AL
ISBN 10: 0126662606 ISBN 13: 9780126662603
New Quantity Available: 5
International Edition
Seller
Bookshub
(Karol Bagh, India)
Rating
[?]

Book Description Book Condition: New. New. International edition. Perfect condition. Ship by express service to USA, Canada, Australia, France, Italy, UK, Germany and Netherland. Customer satisfaction our priority. Bookseller Inventory # ABE-FEB-92853

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 25.84
Convert Currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, Rates & Speeds
International Edition
International Edition

8.

Gregory N. Stephanopoulos
ISBN 10: 0126662606 ISBN 13: 9780126662603
New Paperback Quantity Available: 5
International Edition
Seller
PRIORITY BOOKS
(springfield, VA, U.S.A.)
Rating
[?]

Book Description Paperback. Book Condition: New. Softcover Book, Condition: New. 1st Edition. [Please Read Carefully Before Buying], This Is An International Edition. Printed In Black and White. 725 pages, Book Cover And ISBN No May Be Different From US Edition. Restricted Sales Disclaimer Wordings Not For Sales In USA And Canada May Be Printed On The Cover Of The Book. Standard Shipping 7-14 Business Days. Expedited Shiping 4-8 Business Days. ***WE DO NOT ENTERTAIN BULK ORDERS.*** The Books May Be Ship From Overseas For Inventory Purpose. Bookseller Inventory # 282999

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 22.05
Convert Currency

Add to Basket

Shipping: US$ 3.99
Within U.S.A.
Destination, Rates & Speeds
International Edition
International Edition

9.

Gregory N. Stephanopoulos
ISBN 10: 0126662606 ISBN 13: 9780126662603
New Paperback Quantity Available: 1
International Edition
Seller
Nick Book House
(fresno, CA, U.S.A.)
Rating
[?]

Book Description Paperback. Book Condition: New. New Softcover International Edition, Printed in Black and White, Only USPS Media mail Shipping ONLY, Different ISBN, Same Content As US edition, Book Cover may be Different, in English Language. Bookseller Inventory # 975

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 23.10
Convert Currency

Add to Basket

Shipping: US$ 3.99
Within U.S.A.
Destination, Rates & Speeds
International Edition
International Edition

10.

Stephanapoulus
ISBN 10: 0126662606 ISBN 13: 9780126662603
New Softcover Quantity Available: 5
International Edition
Seller
Romtrade Corp.
(STERLING HEIGHTS, MI, U.S.A.)
Rating
[?]

Book Description Book Condition: New. Brand New Paperback International Edition.We Ship to PO BOX Address also. EXPEDITED shipping option also available for faster delivery. Bookseller Inventory # AUSBNEW-6646

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 27.97
Convert Currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, Rates & Speeds

There are more copies of this book

View all search results for this book