Excitatory Amino Acids and Synaptic Transmission, Second Edition - Hardcover

Hardcover

ISBN 10: 0127460314 ISBN 13: 9780127460314

Publisher: Academic Press, 1995

Synopsis

Excitatory amino acids (EAAs) as neurotransmitters are the subject of vast and rapidly expanding interest. The First Edition of Excitatory Amino Acids and Synaptic Transmission was the first text to provide anoverview of the function of EAAs in transmission at the synapses and in the organization of the nervous system. The First Edition is a well-respected reference text for neuroscience researchers; it provides a comprehensive account of the physiological, pharmacological, chemical, molecular, biological, and neural networking aspects of the EAAs.
The Second Edition has been revised so that its text is even more user-friendly; plus its coverage has been expanded to include the up-to-date approaches of molecular biology and biophysics. The well-praised explanatory glossary has also been improved.

About this title

From the Back Cover

Excitatory amino acids are the transmitters at the vast majority of fast, excitatory synapses within the mammalian central nervous system.
This volume integrates up-to-date molecular biology and biophysics with the traditional approaches of physiology, pharmacology and biochemistry to provide a broad understanding of the role of excitatory amino acids at CNS synapses.
It is intended for all those involved in research in this field and for students of neurobiology who need a comprehensive reference text on the subject. An extensive glossary of terms helps the less expert reader where individual chapters do not permit complete explanations.
The three-dimensional reconstruction of a thalamo-cortical presynaptic bouton [in orange on the front cover, blue mesh on back cover] contacting three postsynaptic targets [dendritic spines, coloured blue on both front and back cover] in visual cortex, was provided by M J Friedlander and K A C Martin with image reconstruction by J Gemmill and D McCarthy. Neurobiology Research Center, University of Alabama at Birmingham. The presynaptic axon was recorded intracellularly, filled with HRP, and the bouton reconstructed from over fifty digitised serial EM sections.
The three-dimensional reconstruction of a hippocampal pyramidal neuron was provided by Howard Wheal.

About the Author

For the past 18 years, Dr. Angus Thomson has been involved at the forefront of developments in cellular and molecular immunology as they apply to our further understanding of the immune system and how they can more effectively be regulated to control adverse immune reactions that occur in autoimmune disorders, transplant rejection, and allergy.

Edition details

• Publisher: Academic Press
• Publication date: 1995
• ISBN 10: 0127460314
• ISBN 13: 9780127460314
• Binding: Hardcover
• Language: English
• Edition number: 2
• Number of pages: 388