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Trafficking of GPCRs (Volume 132) (Progress in Molecular Biology and Translational Science, Volume 132) - Hardcover
Synopsis
G protein-coupled receptors (GPCRs) constitute the largest superfamily of cell surface receptors that regulate a variety of cell functions. Over the past few decades great progress has been made in defining the roles of intracellular trafficking in controlling the functionality of the receptors as well as in the development of various human diseases. This volume of Progress in Molecular Biology and Translational Science reviews the recent understanding of GPCR trafficking regulators and molecular mechanisms.
- Written by future leaders in the pain field
- Covers a wide range of targets
- Contains provocative ideas about GPCR trafficking
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About the Author
Dr. Guangyu Wu, the editor of this book, is a professor in the Department of Pharmacology and Toxicology at the Medical College of Georgia, Georgia Regents University. The long term goal of Dr. Wu’s research effort is to define the molecular mechanisms underlying the intracellular trafficking and signal propagation of GPCRs. Dr. Wu’s research at the earlier stages, as a graduate student and a post-doctoral fellow, was mainly on the GPCR pharmacology and signal transduction pathways. Since starting his own laboratory in the Department of Pharmacology at Louisiana State University Health Sciences Center New Orleans, Dr. Wu has focused his research on the regulation of GPCR export from the endoplasmic reticulum through the Golgi apparatus to the cell surface through studying the function of well-defined transport machinery at different intracellular organelles and defining specific motifs embedded within the receptors that direct receptor export from the ER/Golgi or cell surface transport.
"About this title" may belong to another edition of this title.
- PublisherAcademic Press
- Publication date2015
- ISBN 10 0128029390
- ISBN 13 9780128029398
- BindingHardcover
- LanguageEnglish
- Edition number1
- Number of pages328
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Trafficking of GPCRs: 132 (Progress in Molecular Biology and Translational Science): Volume 132
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