Modeling and Control of Infectious Diseases in the Host: With MATLAB and R - Softcover

Hernandez-Vargas, Esteban A.

 
9780128130520: Modeling and Control of Infectious Diseases in the Host: With MATLAB and R
Softcover
ISBN 10: 0128130520 ISBN 13: 9780128130520
Publisher: Academic Press, 2019

Synopsis

Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R.

  • Provides a multi-scale framework to link within-host infection dynamics (individual level) to between-host transmission fitness (epidemiological level) in viral infectious diseases
  • Includes PK/PD modeling and simulation approaches to improve efficiency and decision-making at preclinical development phases
  • Presents a theoretic approach to schedule drug treatments

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About the Author

Dr. Esteban A. Hernandez-Vargas is a Professor at the Frankfurt Institute for Advanced Studies, Germany, and a research group leader and principal investigator at the Institute of Mathematics (UNAM, Mexico). He obtained his Ph.D. in Mathematics from the Hamilton Institute at the National University of Ireland. In July 2014, he founded the pioneering research group of Systems Medicine of Infectious Diseases at the Helmholtz Centre for Infection Research (HZI). He is a member of the Society of Mathematical Biology, the European Society of Virology, and the Mexican Research Council (CONACYT). Additionally, he is an Editorial Board member of Plos One, Journal of Franklin Institute, as well as a Research Topic Editor at Frontiers of Microbiology and Frontiers of Immunology.

"About this title" may belong to another edition of this title.

Publisher
Academic Press
Publication date
2019
Language
English
ISBN 10 
0128130520
ISBN 13 
9780128130520
Binding
Paperback
Edition number
1
Number of pages
256