Drugs and Behavior: An Introduction to Behavioral Pharmacology (5th Edition)

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9780130481184: Drugs and Behavior: An Introduction to Behavioral Pharmacology (5th Edition)

This accessible, comprehensive book provides the reader with a thorough introduction to the field of behavioral pharmacology and prepares one to analyze drug information from a variety of sources. The text describes the effects of drugs on behavior, facilitating an understanding of both the actions of drugs and the way people use them. Starting with an overview of basic pharmacology, the book is divided by chapter into each class of drugs, and explains the historical and social contexts of each. It covers alcohol, tranquilizers and sedative hypnotics, inhaled substances, tobacco and nicotine, caffiene and the methylxanthines, psychomotor stimulants, the opiates, antipsychotic drugs, antidepressants and mood stimulators, cannabis, and hallucinogens. For those working in the fields of behavioral psychology, psychopharmacology, and pharmacists, doctors, nurses, and others in the medical profession.

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Designed for students from diverse backgrounds, this highly accessible text provides students with a thorough background in the field of behavioral pharmacology and prepares them to analyze drug information from a variety of sources. Written in a clear and sensible manner, it not only describes the effects of drugs on behavior, but also the various ways that behavior principles facilitate an understanding of both the actions of drugs and the way people use them. Each chapter provides comparable information on many classes of both drugs of abuse and psychotherapeutic drugs, including their neurophysiological mechanism of action, their effects on behavior, and a discussion of the historical and social context in which the drug is used.

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The study of drug use and drug effects is fast moving and exciting; it is a rapidly expanding field where new developments, discoveries, and insights are happening every day. Perhaps one of the more exciting aspects of drug research is that it is truly multidisciplinary, encompassing pharmacology, neuroanatomy, neurophysiology, epidemiology, endocrinology, psychology, and more recently, economics, to name a few. This text is primarily about the application of behavioral research (traditionally referred to as psychology) to understanding the effects of drugs and the use of drugs. Because the field is made up of so many disciplines, it is impossible to consider the role of behavioral science in isolation. In this book, the role of behavioral research is placed in the context of the contributions of these other disciplines.

Within the last few years, most of the serious advances in drug research have been made in the area of psychology and neuroscience as it applies to understanding why people and other animals use drugs. These advances were discussed in the fourth edition. In this, the fifth edition, attention has been shifted back to the drugs currently being used. A whole new chapter has been added that discusses the inhaled solvents and anesthetics, and other chapters have been updated to include a discussion of other substances whose use has expanded in recent years. These include a discussion of "club drugs" such as dextromethorphan covered in the chapter on opiates, ecstasy and ketamine in the hallucinogen chapter, and flunitrazepam (Rohypnol) and GHB in the benzodiazepine chapter. The chapter on barbiturates and benzodiazepines has been shortened, and now concentrates primarily on the benzodiazepines to reflect the changing patterns of use, both medical and illicit, of both these drugs.

Like the fourth edition, the fifth edition does not have a glossary. I have attempted to design the index to fill the function of a glossary. You will notice that for the entries for important concepts that previously would have been in a glossary, the page of the definitive discussion of the concept is indicated in bold print. This should permit the student to locate instantly the appropriate definition of any concept as well as a more extended discussion of it, not just a cursory and necessarily constrained glossary definition.

This book would not have been possible without the assistance of marry people. These include those mentioned in the earlier editions. In this edition, I would like to acknowledge the help of my wife Edna McKim who not only assisted with many technical matters but tolerated my absence, both physical and mental, while the book was being written, my colleagues, both at Memorial University and many other institutions around the world who read many drafts, sent me manuscripts, pointed out many errors and made many suggestions, my students who suffered through many teaching experiments and nearly unreadable drafts of the manuscript, and the technical and office staff in the Psychology Department at Memorial University. All these people include, but are not limited to

Rob Brown, Geoff Carre, Marilyn Carroll, Jamie Drover, Harriet de Wit, Shola Elabanjo, Kim French, Carolyn Harley, John Harvey, Peter Heinen, Gene Heyman, Julia Lang, Bow Tong Lett, Gerard Martin, Paul Mattless, James S. MacDonall, Andrew McKim, Edna McKim, Heather McKim, Kathleen McKim, Brenda Noftle, John Podd, Sam Revusky, Brandi Smith, John Scott, Bernice St. Croix, Bernie Weiss, Bill Wolverton, and Jim Zacny.

I would also like to acknowledge the helpful comments of Cheryl Kirstein, University of South Florida; John M. Morgan, Humboldt State University; Raymond Sanchez Mayers, Rutgers University; Daniel J. Calcagnetti, Farleigh Dickinson University; and Tom Byrne, Massachusetts College of Liberal Arts who reviewed this manuscript for the publisher.

Apart from taking credit where such is due, none of these people can be held in any way responsible for any errors or problems in the book because I did not always follow the advice I was given.

William A. McKim
St. John's

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