Modulation of Cardiac Calcium Sensitivity: A New Approach to Increasing the Strength of the Heart (Oxford Medical Publications) - Hardcover

Book 16 of 208: Oxford Medical Publications
 
9780192623478: Modulation of Cardiac Calcium Sensitivity: A New Approach to Increasing the Strength of the Heart (Oxford Medical Publications)

Synopsis

Calcium sensitizers are a new class of drug which increases the force of contraction of the heart by increasing the calcium sensitivity of contractile proteins. Their development represents the first major innovation in the treatment of heart failure for over 200 years. Unlike other drugs in this area, they do not increase the intracellular calcium concentration and do not have the side effects associated with that mechanism of action. These drugs offer an alternative approach to the treatment of heart failure. The volume provides an authoritative overview of the physiology, biochemistry and clinical issues involved.

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Review

'At GBP45, it will be most readily available in the well found library, where it may stimulate the enquiring student.' R.A. Chapman, Cardiovascular Research, May 1994

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