Clinical Trials: Design, Conduct, and Analysis (Monographs in Epidemiology and Biostatistics)

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9780195035681: Clinical Trials: Design, Conduct, and Analysis (Monographs in Epidemiology and Biostatistics)
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The definitive reference work on clinical trials, this book presents a wealth of detailed, practical information on the design, conduct, and analysis of both single center and multicenter trials. No other book on clinical trials offers as much detail as Meinert does on such issues as sample size calculation, stratification and randomization, data systems design, consent form development, publication policies, preparation of funding requests, and reporting procedures.

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About the Author:

Curtis L. Meinert is at The Johns Hopkins University.

Review:

"The most thorough and informative volume on the subject printed so far. In an extremely systematic way most of the pertinent methodological questions are analysed, and thoughtful guidelines provided....A must for all medium size and larger libraries and for those actively involved in clinical trials."--Pain

"Comprehensive as most others on the topic are not, and thorough in most respects, the book also contains a glossary, many useful summary appendices, and much practical advice."--British Medical Journal

"A good reference for many practitioners of clinical trials.... This book has many tables and figures representing the actual data from previous clinical trials, which helps maintain interest for the clinical investigator.... The bibliography is particularly well done and includes not only the extensive documentation for the text, but also classic statistical papers... This book would serve as a good reference for anyone engaged in designing, implementing, or conducting a clinical trial."--Journal of the American Medical Association

"Covers with great thoroughness the design, execution, and reporting of multicenter and single-center uncrossed trials that have a clinical event as endpoint....Both the authors and the publisher are to be congratulated on the skill with which this complex book was put together...Will be the standard for instruction in and evaluation of controlled clinical trials for years to come."--The Lancet

"Scarcely any aspect of the design, organization and analysis of clinical trials is neglected....However, the presentation of the material allows it to be a book both for beginners and for readers already familiar with clinical trials. I believe it would be better to buy Dr. Meinert's book than to acquire an elementary test on clinical trials with the hope of filling the gaps from the literature."--Canadian Journal of Public Health

"[The] checklists and examples provide excellent guidance, and the text would be a valuable resource in the library of even the most experienced clinical investigators."--European Organization for Research and Treatment of Cancer

"A large amount of practical information on the design, conduct and analysis of both single centre and multi-centre trials is contained in this volume."--Short Book Reviews

"Clearly and logically presents material on each stage of a clinical trial, which should be of interest both to practitioners and to a wider statistical audience." --Royal Statistical Society

"This book is a practical manual which would be very useful for anyone about to create a clinical trials office....Recommended to specialist clinical trial centres." --Human Psychopharmacology

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