Items related to Cancer Biology
Synopsis
Substantially expanded in its second edition, Cancer Biology incorporates the important recent advances in research on the cellular and molecular biology of cancer and provides a comprehensive discussion of the mechanisms of carcinogenesis. The text describes the malignant transformation of cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of diseased cells into the host organism. In addition to a new chapter on the biology of tumor metastasis, there are three new chapters on cancer causation, dealing with the chemical and physical carcinogens; viruses and oncogenes; and chromosomal abnormalities and gene depression. Updated material on growth factors and their receptors, differentiation, and the cell matrix is also presented, and the pathophysiology of cancer as a clinical disease is discussed. Praise for the first edition: "Highly recommended for readers who wish to spend several hours with a well-written, well-selected, effectively illustrated, and well-integrated overview of the sciences that join to make up the field of tumor biology."-- The New England Journal of Medicine. "I can think of no better introduction for a graduate student to contemporary cancer research, especially at the cellular level."--G.A. Currie in The Times Higher Education Supplement. "Ruddon provides a status report in a rapidly moving field. The material is will presented and current, and includes excellent essays on differentiation, phenotype expression, genetic mutation, and tumor growth.... A welcome contrast to multiauthor oncologic behemoths that are too heavy to carry and too expensive to acquire."--Journal of the American Medical Association
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About the Author
Raymond W. Ruddon is at Johnson and Johnson.
Review
"Provides a thorough, yet concise review of the cellular and molecular mechanisms involved in the transformation of normal into malignant cells...Clearly written and well illustrated, there is also an extensive, up-to-date bibliography, making the book valuable to basic scientists, physicians, nurses, and students interested in the field."--Anticancer Research
"Provides a thorough, yet concise review of the cellular and molecular mechanisms involved in the transformation of normal into malignant cells...Clearly written and well illustrated, there is also an extensive, up-to-date bibliography, making the book valuable to basic scientists, physicians, nurses, and students interested in the field."--Anticancer Research
"Excellent chapters cover the major topics in cancer biology and include extensive bibilography sections...Overall this is a well crafted book for graduate students and cancer researchers who wish to learn more about the key concepts and pathways involved in the rapidly advancing field of cancer biology."--Doody's
"Cancer Biology is a single-authored volume that contains nine chapters and over 500 pages of primary text. The author writes from a unique perspective, having assembled the first edition of this book in 1981, and he provides a historical perspective that is unusually appropriate, citing the relevant literature and reproducing some of the figures from 'classic' papers, while at the same time covering more contemporary topics with high scholarship. His narrative is exceptionally well written, interesting, and accessible...Overall, this is an extremely valuable volume that will be of great use to both students and established investigators."--David J. McConkey, MD, as reviewed in The Quarterly Review of Biology
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